Results 81 to 90 of about 166,597 (269)

Neonatal Urine Screening Program in the Province of Quebec: Technological Upgrade from Thin Layer Chromatography to Tandem Mass Spectrometry

International Journal of Neonatal Screening, 2021
The Quebec Neonatal Urine Screening Program was initiated in 1971 with overall screening inception of newborns in 1973. Forty-seven years later, over 3.5 million babies have been screened for up to 25 inborn errors of metabolism divided into two groups: (
Christiane Auray-Blais, Michel Boutin, Pamela Lavoie, Bruno Maranda   +3 more
doaj   +1 more source

Berries: Health Effects via Modulation of the Gut Microbiota

Food Frontiers, EarlyView.
ABSTRACT Berries are widely regarded as beneficial foods, rich in polyphenols, flavonoids, and other bioactive compounds that could positively influence human health. Although the gut microbiota plays a crucial role in metabolism and physiology of humans, the interaction between berries and human gut microbiota activity remains unclear.
Manjin Xu, Yunfeng Xu, Lizhi Wu, Huixia Niu, Bei Gao, Kai Sun, Xueqing Li, Mingluan Xing, Zhe Mo, Zhijian Chen, Pengcheng Tu, Xiaoming Lou   +11 more
wiley   +1 more source

Fibroblasts and hiPS‐Derived Astrocytes From CoPAN Patients Showed Different Levels of Iron Overload Correlated With Senescent Phenotype

Glia, EarlyView.
CoPAN affects CoA biosynthesis and leads to iron dyshomeostasis. CoPAN d‐astrocytes show ferroptosis, iron accumulation, senescence, lipid peroxidation, mitochondrial damage and tubulin acetylation loss. Astrocytes recapitulate CoPAN disease. ABSTRACT COASY protein‐associated neurodegeneration (CoPAN) is a rare autosomal recessive disorder within the ...
Anna Cozzi, Paolo Santambrogio, Andrea Stefano Moro, Alessio Pelagatti, Alicia Rubio, Chiara Balestrucci, Ivano Di Meo, Valeria Tiranti, Sonia Levi   +8 more
wiley   +1 more source

Phenotyping, genome‐wide dissection, and prediction of maize root architecture for temperate adaptability

iMeta, EarlyView.
This study dissects the genetic architecture of maize Root System Architecture, identifying significant root trait differences between tropical/subtropical and temperate lines. Using genome‐wide association study, 3511 genes were linked to root morphology, weight, and slice traits.
Weijun Guo, Fanhua Wang, Jianyue Lv, Jia Yu, Yue Wu, Hada Wuriyanghan, Liang Le, Li Pu   +7 more
wiley   +1 more source

Illuminating Immunity: A Systematic Review of Immune Cell Autofluorescence

Journal of Biophotonics, EarlyView.
ABSTRACT Immunophenotyping provides valuable prognostic and diagnostic information, but is technically complex and expensive. The assessment of autofluorescence is label‐free and provides complex information on cell identity. However, research on its application to immunophenotyping has been heterogenous.
Aline Knab, Caroline Giardina, Shane T. Grey, Ewa M. Goldys, Jared M. Campbell   +4 more
wiley   +1 more source

Amino acid metabolism conflicts with protein diversity [PDF]

arXiv, 2014
The twenty protein coding amino acids are found in proteomes with different relative abundances. The most abundant amino acid, leucine, is nearly an order of magnitude more prevalent than the least abundant amino acid, cysteine. Amino acid metabolic costs differ similarly, constraining their incorporation into proteins.
arxiv  

Demographic and Clinical Findings in Pediatric Patients Affected by Organic Acidemia [PDF]

, 2016
How to Cite This Article: Najafi R, Hashemipour M, Mostofizadeh N, Ghazavi MR, Nasiri J, Shahsanai A, Famori F, Najafi F, Moafi M. Demographic and Clinical Findings in Pediatric Patients Affected by Organic Acidemia. Iran J Child Neurol.
FAMORI, Fatemeh, GHAZAVI, Mohammadreza, HASHEMIPOUR, Mahin, MOAFI, Mohammad, MOSTOFIZADEH, Neda, NAJAFI, Fatemeh, NAJAFI, Reza, NASIRI, Jafar, SHAHSANAI, Armindokht   +8 more
core   +2 more sources

A 3-Step Process to Estimate Phenylalanine in Commercial Foods for PKU Management

IEEE Access, 2018
Phenylalanine (Phe) is a key nutrient in the dietary management of the metabolic disease phenylketonuria (PKU). To give more freedom to PKU patients, we propose a numerical process to estimate the Phe content of a commercial food using the information ...
Jieun Kim, Amruthavarshini Talikoti, Mireille Boutin   +2 more
doaj   +1 more source

A Realistic Model under which the Genetic Code is Optimal [PDF]

, 2013
The genetic code has a high level of error robustness. Using values of hydrophobicity scales as a proxy for amino acid character, and the Mean Square measure as a function quantifying error robustness, a value can be obtained for a genetic code which reflects the error robustness of that code.
arxiv   +1 more source

Term infant formula macronutrient composition: An update for clinicians

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Protein, carbohydrates, and fats comprise the macronutrient components of infant formulas. While all infant formulas in the United States meet specific nutrition standards, the macronutrient composition of formulas is diverse. Each macronutrient in the formula may play a role in treating or managing the disease.
Catherine Larson‐Nath, Anam Bashir, Rachel E. Herdes, Bridget Kiernan, Joanne Lai, Nicole Martin, Nicole Misner, Akash Pandey, Kanika Puri, Wenjing Zong, Debora Duro   +10 more
wiley   +1 more source