Results 11 to 20 of about 1,085,115 (255)

Oncology Therapeutics Targeting the Metabolism of Amino Acids

open access: yesCells, 2020
Amino acid metabolism promotes cancer cell proliferation and survival by supporting building block synthesis, producing reducing agents to mitigate oxidative stress, and generating immunosuppressive metabolites for immune evasion.
Nefertiti Muhammad   +2 more
doaj   +1 more source

Integrated nontargeted and targeted metabolomics analyses amino acids metabolism in infantile hemangioma

open access: yesFrontiers in Oncology, 2023
Infantile hemangioma (IH) is the most common benign tumor in children. However, the exact pathogenesis of IH remains unclear. Integrated nontargeted and targeted metabolic analyses were performed to obtain insight into the possible pathogenic mechanism ...
Kaiying Yang   +7 more
doaj   +1 more source

Asparagine promotes cancer cell proliferation through use as an amino acid exchange factor. [PDF]

open access: yes, 2016
Cellular amino acid uptake is critical for mTOR complex 1 (mTORC1) activation and cell proliferation. However, the regulation of amino acid uptake is not well-understood.
Braas, Daniel   +4 more
core   +1 more source

Research Progress of Amino Acid Metabolism PET Imaging in Tumor

open access: yesJournal of Isotopes, 2015
Amino acid metabolism PET imaging plays a very important role in metabolism molecular imaging. Amino acid PET tracers include [1-11C]amino acid, labeling α-C amino acid, labeling side-chain amino acid, and N-substituted labeling amino acid.
NIE Da-hong, TANG Gang-hua2
doaj   +1 more source

Increased amino acid turnover and myofibrillar protein breakdown in advanced cancer are associated with muscle weakness and impaired physical function [PDF]

open access: yes, 2018
Muscle wasting in cancer negatively affects physical function and quality of life. This study investigates amino acid metabolism and the association with muscle mass and function in patients with cancer.In 16 patients with advanced cancer undergoing ...
Deutz, Nicolaas E P   +3 more
core   +1 more source

Connections Between Amino Acid Metabolisms in Plants: Lysine as an Example

open access: yesFrontiers in Plant Science, 2020
Extensive efforts have been made to fortify essential amino acids and boost nutrition in plants, but unintended effects on growth and physiology are also observed.
Qingqing Yang   +4 more
doaj   +1 more source

Multi-Omics Data Reveal Amino Acids Related Genes in the Common Carp Cyprinus carpio

open access: yesFishes, 2022
Amino acids have important physiological effects on fish growth and development and are essential nutrition for humans. Flavor-related amino acids, such as glutamic acid and glycine, could have a significant effect on the taste of fish flesh.
Hanyuan Zhang   +8 more
doaj   +1 more source

Different Effects of Maternal Low-Isoflavone Soy Protein and Genistein Consumption on Hepatic Lipid Metabolism of 21-Day-Old Male Rat Offspring. [PDF]

open access: yes, 2017
Amino acid composition and isoflavone are alleged contributors to the beneficial effects of soy protein isolate (SPI) on lipid metabolism. Therefore, we investigated the contributing component(s) of SPI in a maternal diet to the regulation of lipid ...
Han, Anna, Kwon, Young Hye, Won, Sae Bom
core   +3 more sources

Determination of a steady-state isotope dilution protocol for carbon oxidation studies in the domestic cat

open access: yesJournal of Nutritional Science, 2023
The present study aimed to develop an isotope protocol to achieve equilibrium of 13CO2 in breath of cats during carbon oxidation studies using L-[1-13C]-Phenylalanine (L-[1-13C]-Phe), provided orally in repeated meals.
Julia Guazzelli Pezzali   +3 more
doaj   +1 more source

Regulatory effects of blood constituents on the function and metabolism of the cat brain in perfusion ezperiments. Brain perfusion with artificial blood containing low molecular dextran and amino acids [PDF]

open access: yes, 1967
As a link in a series of studies on the effects of blood constituents on the brain function by means of brain perfusion, we used four kinds of artificial blood; namely, the blood containing a low molecular dextran, one containing glutamic acid, one ...
Edamatsu, Kazuyasu   +5 more
core   +1 more source

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