Results 41 to 50 of about 1,085,115 (255)

Amino Acid and Fatty Acid Metabolism Disorders Trigger Oxidative Stress and Inflammatory Response in Excessive Dietary Valine-Induced NAFLD of Laying Hens

open access: yesFrontiers in Nutrition, 2022
Non-alcoholic fatty liver disease (NAFLD) is a chronic and metabolic liver disease and commonly occurs in humans with obesity and type 2 diabetes mellitus (T2DM); such a condition also exists in animals such as rodents and laying hens.
Huafeng Jian   +44 more
doaj   +1 more source

Branched-Chain Amino Acid Negatively Regulates KLF15 Expression via PI3K-AKT Pathway. [PDF]

open access: yes, 2017
Recent studies have linked branched-chain amino acid (BCAA) with numerous metabolic diseases. However, the molecular basis of BCAA's roles in metabolic regulation remains to be established.
Dong, Weibing   +5 more
core   +2 more sources

Targeting amino acid in tumor therapy

open access: yesFrontiers in Oncology
Tumor cells undergo profound metabolic reprogramming to sustain their rapid growth and proliferation, with amino acids serving as essential nutrients critical for protein synthesis, energy metabolism, nucleotide production, and redox balance.
Mingpai Ge   +5 more
doaj   +1 more source

Regulation of amino acid metabolism in Aphis gossypii parasitized by Binodoxys communis

open access: yesFrontiers in Nutrition, 2022
The vast majority of parasitoids are capable of precise and meticulous regulation of nutrition and metabolism within the host. An important building block of life, amino acids are critical to the development of parasitoids.
Hui Xue   +21 more
doaj   +1 more source

Targeting amino acid metabolism to inhibit gastric cancer progression and promote anti-tumor immunity: a review

open access: yesFrontiers in Immunology
The incidence of gastric cancer remains high and poses a serious threat to human health. Recent comprehensive investigations into amino acid metabolism and immune system components within the tumor microenvironment have elucidated the functional ...
Yuchun Jiang   +12 more
doaj   +1 more source

Dysregulated Choline, Methionine, and Aromatic Amino Acid Metabolism in Patients with Wilson Disease: Exploratory Metabolomic Profiling and Implications for Hepatic and Neurologic Phenotypes. [PDF]

open access: yes, 2019
Wilson disease (WD) is a genetic copper overload condition characterized by hepatic and neuropsychiatric symptoms with a not well-understood pathogenesis.
Czlonkowska, Anna   +6 more
core   +2 more sources

Transcriptional regulation of amino acid metabolism in response to nitrogen deficiency and nitrogen forms in tea plant root (Camellia sinensis L.)

open access: yesScientific Reports, 2020
Free amino acids, including theanine, glutamine and glutamate, contribute greatly to the pleasant taste and multiple health benefits of tea. Amino acids in tea plants are mainly synthesized in roots and transported to new shoots, which are significantly ...
Tianyuan Yang   +9 more
doaj   +1 more source

The degradation of L-lysine in guinea pig liver homogenate: formation of alpha-aminoadipic acid [PDF]

open access: yes, 1948
A summary of the little that is known of the metabolism of lysine in animals is as follows: it is indispensable in the diet, its α-amino group does not participate in reversible transamination reaction in vivo (2), neither the L nor D form is attacked by
Borsook, Henry   +4 more
core   +1 more source

Ammonia production by human faecal bacteria, and the enumeration, isolation and characterization of bacteria capable of growth on peptides and amino acids [PDF]

open access: yes, 2013
DA - 20130125 IS - 1471-2180 (Electronic) IS - 1471-2180 (Linking) LA - eng PT - Journal Article PT - Research Support, Non-U.S.
McKain, Nest   +2 more
core   +2 more sources

Medium alkalization due to carbon metabolism is largely responsible for inhibition of bacterial growth by Vibrio cholerae supernatants [PDF]

open access: yes, 2017
Vibrio cholerae is the causative agent of the diarrheal disease cholera. Many Vibrio species secrete antimicrobial factors, though the identity of such a factor has not been determined for any V. cholerae strain.
Becker, Miranda
core   +1 more source

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