Non-alcoholic fatty liver disease (NAFLD) is a chronic and metabolic liver disease and commonly occurs in humans with obesity and type 2 diabetes mellitus (T2DM); such a condition also exists in animals such as rodents and laying hens.
Huafeng Jian+44 more
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Branched-Chain Amino Acid Negatively Regulates KLF15 Expression via PI3K-AKT Pathway. [PDF]
Recent studies have linked branched-chain amino acid (BCAA) with numerous metabolic diseases. However, the molecular basis of BCAA's roles in metabolic regulation remains to be established.
Dong, Weibing+5 more
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Targeting amino acid in tumor therapy
Tumor cells undergo profound metabolic reprogramming to sustain their rapid growth and proliferation, with amino acids serving as essential nutrients critical for protein synthesis, energy metabolism, nucleotide production, and redox balance.
Mingpai Ge+5 more
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Regulation of amino acid metabolism in Aphis gossypii parasitized by Binodoxys communis
The vast majority of parasitoids are capable of precise and meticulous regulation of nutrition and metabolism within the host. An important building block of life, amino acids are critical to the development of parasitoids.
Hui Xue+21 more
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The incidence of gastric cancer remains high and poses a serious threat to human health. Recent comprehensive investigations into amino acid metabolism and immune system components within the tumor microenvironment have elucidated the functional ...
Yuchun Jiang+12 more
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Dysregulated Choline, Methionine, and Aromatic Amino Acid Metabolism in Patients with Wilson Disease: Exploratory Metabolomic Profiling and Implications for Hepatic and Neurologic Phenotypes. [PDF]
Wilson disease (WD) is a genetic copper overload condition characterized by hepatic and neuropsychiatric symptoms with a not well-understood pathogenesis.
Czlonkowska, Anna+6 more
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Free amino acids, including theanine, glutamine and glutamate, contribute greatly to the pleasant taste and multiple health benefits of tea. Amino acids in tea plants are mainly synthesized in roots and transported to new shoots, which are significantly ...
Tianyuan Yang+9 more
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The degradation of L-lysine in guinea pig liver homogenate: formation of alpha-aminoadipic acid [PDF]
A summary of the little that is known of the metabolism of lysine in animals is as follows: it is indispensable in the diet, its α-amino group does not participate in reversible transamination reaction in vivo (2), neither the L nor D form is attacked by
Borsook, Henry+4 more
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Ammonia production by human faecal bacteria, and the enumeration, isolation and characterization of bacteria capable of growth on peptides and amino acids [PDF]
DA - 20130125 IS - 1471-2180 (Electronic) IS - 1471-2180 (Linking) LA - eng PT - Journal Article PT - Research Support, Non-U.S.
McKain, Nest+2 more
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Medium alkalization due to carbon metabolism is largely responsible for inhibition of bacterial growth by Vibrio cholerae supernatants [PDF]
Vibrio cholerae is the causative agent of the diarrheal disease cholera. Many Vibrio species secrete antimicrobial factors, though the identity of such a factor has not been determined for any V. cholerae strain.
Becker, Miranda
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