Results 11 to 20 of about 24,002 (247)

Reconstructing a Flavodoxin Oxidoreductase with Early Amino Acids [PDF]

International Journal of Molecular Sciences, 2013
Primitive proteins are proposed to have utilized organic cofactors more frequently than transition metals in redox reactions. Thus, an experimental validation on whether a protein constituted solely by early amino acids and an organic cofactor can perform electron transfer activity is an urgent challenge.
Lu, Ming-Feng, Ji, Hong-Fang, Li, Ting-Xuan, Kang, Shou-Kai, Zhang, Yue-Jie, Zheng, Jue-Fei, Tian, Tian, Jia, Xi-Shuai, Lin, Xing-Ming, Zhang, Hong-Yu   +9 more
openaire   +2 more sources

Characterization of a novel AA3_1 xylooligosaccharide dehydrogenase from Thermothelomyces myriococcoides CBS 398.93

Biotechnology for Biofuels and Bioproducts, 2022
Background The Carbohydrate-Active enZymes (CAZy) auxiliary activity family 3 (AA3) comprises flavin adenine dinucleotide-dependent (FAD) oxidoreductases from the glucose–methanol–choline (GMC) family, which play auxiliary roles in lignocellulose ...
Hongbo Zhao, Johanna Karppi, Thi Truc Minh Nguyen, Annie Bellemare, Adrian Tsang, Emma Master, Maija Tenkanen   +6 more
doaj   +1 more source

Structure of Alcohol Oxidase from Pichia pastoris by Cryo-Electron Microscopy. [PDF]

PLoS ONE, 2016
The first step in methanol metabolism in methylotrophic yeasts, the oxidation of methanol and higher alcohols with molecular oxygen to formaldehyde and hydrogen peroxide, is catalysed by alcohol oxidase (AOX), a 600-kDa homo-octamer containing eight FAD ...
Janet Vonck, David N Parcej, Deryck J Mills   +2 more
doaj   +1 more source

Reduction of Protein Bound Methionine Sulfoxide by a Periplasmic Dimethyl Sulfoxide Reductase

Antioxidants, 2020
In proteins, methionine (Met) can be oxidized into Met sulfoxide (MetO). The ubiquitous methionine sulfoxide reductases (Msr) A and B are thiol-oxidoreductases reducing MetO.
Lionel Tarrago, Sandrine Grosse, David Lemaire, Laetitia Faure, Mathilde Tribout, Marina I. Siponen, Mila Kojadinovic-Sirinelli, David Pignol, Pascal Arnoux, Monique Sabaty   +9 more
doaj   +1 more source

Molecular Characterization and Expression Analysis of a Novel Glutaredoxin 3 Gene in Pacific White Shrimp (Litopenaeus vannamei)

Frontiers in Marine Science, 2021
Glutaredoxins (Grxs), small heat-stable oxidoreductases, are key members of the thioredoxin (Trx) superfamily. Recently, an emerging subclass of Grxs with a cysteine residue in the active site was found in shrimps.
Peihua Zheng, Peihua Zheng, Xiuxia Zhang, Xiuxia Zhang, Dongmei Wang, Dongmei Wang, Juntao Li, Juntao Li, Zelong Zhang, Zelong Zhang, Yaopeng Lu, Yaopeng Lu, Jianan Xian, Jianan Xian, Anli Wang, Lei Wang   +15 more
doaj   +1 more source

Mutations in NADH:ubiquinone oxidoreductase of Escherichia coli affect growth on mixed amino acids [PDF]

Journal of Bacteriology, 1994
We isolated and characterized mutants defective in nuo, encoding NADH dehydrogenase I, the multisubunit complex homologous to eucaryotic mitochondrial complex I. By Southern hybridization and/or sequence analysis, we characterized three distinct mutations: a polar insertion designated nuoG::Tn10-1, a nonpolar insertion designated nuoF::Km-1, and a ...
B M, Prüss, J M, Nelms, C, Park, A J, Wolfe   +3 more
openaire   +2 more sources

Catalytic Importance of Acidic Amino Acids on Subunit NuoB of the Escherichia coli NADH:Ubiquinone Oxidoreductase (Complex I) [PDF]

Journal of Biological Chemistry, 2006
The NADH:ubiquinone oxidoreductase (complex I) from Escherichia coli is composed of 13 subunits called NuoA through NuoN and contains one FMN and 9 iron-sulfur clusters as redox groups. Electron transfer from NADH to ubiquinone is coupled with the translocation of protons across the membrane by a yet unknown mechanism.
Flemming, Dirk, Hellwig, Petra, Lepper, Simone, Kloer, Daniel, Friedrich, Thorsten   +4 more
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Decoding the similarities and differences among mycobacterial species. [PDF]

PLoS Neglected Tropical Diseases, 2017
Mycobacteriaceae comprises pathogenic species such as Mycobacterium tuberculosis, M. leprae and M. abscessus, as well as non-pathogenic species, for example, M. smegmatis and M. thermoresistibile. Genome comparison and annotation studies provide insights
Sony Malhotra, Sundeep Chaitanya Vedithi, Tom L Blundell   +2 more
doaj   +1 more source

A Human-Curated Annotation of the Candida albicans Genome. [PDF]

PLoS Genetics, 2005
Recent sequencing and assembly of the genome for the fungal pathogen Candida albicans used simple automated procedures for the identification of putative genes.
Burkhard R Braun, Marco van Het Hoog, Christophe d'Enfert, Mikhail Martchenko, Jan Dungan, Alan Kuo, Diane O Inglis, M Andrew Uhl, Hervé Hogues, Matthew Berriman, Michael Lorenz, Anastasia Levitin, Ursula Oberholzer, Catherine Bachewich, Doreen Harcus, Anne Marcil, Daniel Dignard, Tatiana Iouk, Rosa Zito, Lionel Frangeul, Fredj Tekaia, Kim Rutherford, Edwin Wang, Carol A Munro, Steve Bates, Neil A Gow, Lois L Hoyer, Gerwald Köhler, Joachim Morschhäuser, George Newport, Sadri Znaidi, Martine Raymond, Bernard Turcotte, Gavin Sherlock, Maria Costanzo, Jan Ihmels, Judith Berman, Dominique Sanglard, Nina Agabian, Aaron P Mitchell, Alexander D Johnson, Malcolm Whiteway, André Nantel   +42 more
doaj   +2 more sources

Unique amino acids cluster for switching from the dehydrogenase to oxidase form of xanthine oxidoreductase [PDF]

Proceedings of the National Academy of Sciences, 2003
In mammals, xanthine oxidoreductase is synthesized as a dehydrogenase (XDH) but can be readily converted to its oxidase form (XO) either by proteolysis or modification of cysteine residues. The crystal structures of bovine milk XDH and XO demonstrated that atoms in the highly charged active-site loop (Gln-423–Lys-433) around ...
Yoshimitsu, Kuwabara, Tomoko, Nishino, Ken, Okamoto, Tomohiro, Matsumura, Bryan T, Eger, Emil F, Pai, Takeshi, Nishino   +6 more
openaire   +2 more sources