Results 61 to 70 of about 24,002 (247)
Advanced Science, EarlyView.A gap‐free genome assembly and multi‐omics comparison of the terrestrial slug Laevichaulis alte with an aquatic relative reveal that expansion of the VEGF family orchestrates mucus production, lipid metabolism, and immune defense—highlighting key molecular innovations for conquering life on land.
Gang Wang +19 more
wiley +1 more source
PLOS ONE, 2018 Helicobacter pylori HP0377 is a thiol oxidoreductase, a member of the CcmG family involved in cytochrome biogenesis, as previously shown by in vitro experiments. In this report, we document that HP0377 also acts in vivo in the cytochrome assembly process in Bacillus subtilis, where it complements the lack of ResA.
Magdalena Joanna Grzeszczuk +8 more
openaire +7 more sources
Subunits of Bakers' Yeast Cytochrome b2 (
European Journal of Biochemistry, 1971 After reduction and carboxymethylation, crystallized cytochrome b2 has been separated by gel filtration into two main fractions and a minor one. The latter is probably an aggregate. The apparent molecular weight of the major fractions has been determined by acrylamide gel electrophoresis in the presence of 0.1% sodium dodecyl sulfate, and found to be ...
F, Lederer, A M, Simon
openaire +2 more sources
Advanced Science, EarlyView.We present a chromosome‐level genome assembly of Siraitia grosvenorii and, through comparative genomics, uncover a conserved UGT73 tandem array driving triterpenoid saponin diversification in Cucurbitaceae. Crystalized SgUGT73AM30 further reveals the regioselectivity mechanism underlying its catalytic activity.
Guangyi Wang +13 more
wiley +1 more source
Protein thiol modifications visualized in vivo. [PDF]
PLoS Biology, 2004 Thiol-disulfide interconversions play a crucial role in the chemistry of biological systems. They participate in the major systems that control the cellular redox potential and prevent oxidative damage.
Lars I Leichert, Ursula Jakob
doaj +1 more source
Advanced Science, EarlyView.An STI‐guided metagenomic association framework links soybean salt‐tolerance phenotypes with rhizosphere microbiome composition and network organization in natural saline soils. The approach identifies candidate beneficial taxa, including Thalassospira xiamenensis, and provides an efficient strategy for mining stress‐protective microbes from native ...
Yu Luo +3 more
wiley +1 more source
Generating functional protein variants with variational autoencoders.
PLoS Computational Biology, 2021 The vast expansion of protein sequence databases provides an opportunity for new protein design approaches which seek to learn the sequence-function relationship directly from natural sequence variation. Deep generative models trained on protein sequence
Alex Hawkins-Hooker +5 more
doaj +1 more source
FEBS Letters, 2005 The NuoF subunit, which harbors NADH‐binding site, of Escherichia coli NADH‐quinone oxidoreductase (NDH‐1) contains five conserved cysteine residues, four of which are predicted to ligate cluster N3. To determine this coordination, we overexpressed and purified the NuoF subunit and NuoF + E subcomplex in E. coli.
Velazquez, Isabel +4 more
openaire +2 more sources
Advanced Science, EarlyView.A multi‐omics framework combining multitissue genome‐wide association studies, metabolomics, transcriptomics, proteomics, and functional validation uncovers the genetic basis of specialized metabolism in quinoa. The study identifies hundreds of metabolite‐associated loci, prioritizes candidate genes for saponin, betalain, and flavonoid biosynthesis ...
Julia von Steimker +11 more
wiley +1 more source
Frontiers in Microbiology, 2020 GmcA is a FAD-containing enzyme belonging to the GMC (glucose-methanol-choline oxidase) family of oxidoreductases. A mutation in the Rhizobium leguminosarum gmcA gene was generated by homologous recombination.
Qian Zou +5 more
doaj +1 more source