Results 131 to 140 of about 1,102,715 (317)

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Discovery of ultrafast myosin, its amino acid sequence, and structural features. [PDF]

Proc Natl Acad Sci U S A, 2022
Haraguchi T, Tamanaha M, Suzuki K, Yoshimura K, Imi T, Tominaga M, Sakayama H, Nishiyama T, Murata T, Ito K.   +9 more
europepmc   +1 more source

Data for amino acid alignment of Japanese stingray melanocortin receptors with other gnathostome melanocortin receptor sequences, and the ligand selectivity of Japanese stingray melanocortin receptors

, 2016
Akiyoshi Takahashi, Perry Davis, Christina Reinick, Kanta Mizusawa, Tatsuya Sakamoto, Robert M. Dores   +5 more
openalex   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Calling the amino acid sequence of a protein/peptide from the nanospectrum produced by a sub-nanometer diameter pore. [PDF]

Sci Rep, 2022
Liu X, Dong Z, Timp G.
europepmc   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source

Targeted modulation of protein liquid-liquid phase separation by evolution of amino-acid sequence. [PDF]

PLoS Comput Biol, 2021
Lichtinger SM, Garaizar A, Collepardo-Guevara R, Reinhardt A.   +3 more
europepmc   +1 more source

The amino acid sequence around the active-site cysteine and histidine residues, and the buried cysteine residues in ficin [PDF]

, 1970
S. Shaukat Husain, Gordon Lowe
openalex   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Taxonomy of Mitochondrial Cytochrome B Proteins of the Same Amino Acid Sequence Length. [PDF]

ScientificWorldJournal, 2021
Zamyatnin AA, Belozerskaya TA, Zamyatnin AA.   +2 more
europepmc   +1 more source