Results 81 to 90 of about 1,102,715 (317)
Progress in Fishery SciencesClock genes play a pivotal role in the rhythm maturation of bony fish ovaries. To explore the role of clock genes in the rhythmic ovarian development and maturation of tongue sole (Cynoglossus semilaevis), we used real-time fluorescent quantitative PCR ...
Kewen YAN +5 more
doaj +1 more source
Multiple sequence alignments of partially coding nucleic acid sequences
BMC Bioinformatics, 2005 Background High quality sequence alignments of RNA and DNA sequences are an important prerequisite for the comparative analysis of genomic sequence data.
Fried Claudia +3 more
doaj +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Accurate prediction of substitution rates at protein sites with a mutation-selection model
Scientific ReportsThe pattern of substitutions at sites in proteins provides invaluable information about their biophysical and functional importance and what selection pressures are acting at individual sites.
Ingemar André
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Amino Acid Sequence of Endothiapepsin [PDF]
European Journal of Biochemistry, 1987 The amino acid sequence of endothiapepsin, the aspartic protease from Endothia parasitica has been determined. The enzyme consists of 330 residues. The sequence determination was performed exclusively at the protein level. The homology of this fungal milk-clotting enzyme with aspartic proteases is demonstrated by alignment with pepsin, chymosin ...
openaire +1 more source
Complete Amino Acid Sequence of Chitinase-A from Leaves of Pokeweed (Phytolacca americana) [PDF]
, 1998 Takeshi Yamagami +3 more
openalex +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Predicting residue-wise contact orders in proteins by support vector regression
BMC Bioinformatics, 2006 Background The residue-wise contact order (RWCO) describes the sequence separations between the residues of interest and its contacting residues in a protein sequence.
Burrage Kevin, Song Jiangning
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The amino acid sequence of a trypsin inhibitor from the seeds of Momordica charantia Linn. Cucurbitaceae [PDF]
, 1988 Fu‐Yue Zeng, Qian Rui-Qing, Yu Wang
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Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source