Results 241 to 250 of about 540,331 (291)

Performance evaluation of amino acid substitution matrices

Proteins: Structure, Function, and Bioinformatics, 1993
AbstractSeveral choices of amino acid substitution matrices are currently available for searching and alignment applications. These choices were evaluated using the BLAST searching program, which is extremely sensitive to differences among matrices, and the Prosite catalog, which lists members of hundreds of protein families.
S, Henikoff, J G, Henikoff
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?-Substituted ?-amino acids

Bulletin of the Academy of Sciences, USSR Division of Chemical Science, 1964
In the bromination of 4-methyl-2-(trifluoromethyl)-2-oxazolin-5-one, 4-bromo-4-(bromomethyl)-2-(trifluoromethyl)-2-oxazolin-5-one is formed. The reactions of this oxazolinone with water, aniline, and 2,4-dinitro-phenylhydrazine were studied.
V. K. Antonov, A. L. Kurts
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Transferrin DChi: The amino acid substitution

Biochemical Genetics, 1968
A peptide difference has been found in the neutral-band (pH 6.4) regions of tryptic digests of human transferrins C and DChi. The peptide has the composition Asp-Ser-Ala-Arg. Therefore, this peptide is proposed as the 2TDChi b peptide, the result of the replacement of histidine by arginine in the Tf C peptide.
P N, Howard, A C, Wang, H E, Sutton
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Novel α-functionally substituted amino acids: diphenylphosphinoglycines

Chem. Commun., 2005
AbstractFor Abstract see ChemInform Abstract in Full Text.
Joachim, Heinicke, Normen, Peulecke, Peter G, Jones   +2 more
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Chiral metals: amino acid-substituted conducting polypyrroles

Synthetic Metals, 1990
Abstract Chiral amino acid groups are substituted on the 3 position of pyrrole. These functionalized monomers are electropolymerized, the high conductivity obtained for the polymers confirming the existence of long conjugated chains. The circular dichroism spectra of these polypyrroles exhibit a large positive Cotton effect, centered on the ...
Didier Delabouglise, Francis Garnier
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Improved insulin stability through amino acid substitution

"Protein Engineering, Design and Selection", 1992
Insulin analogs designed to decrease self-association and increase absorption rates from subcutaneous tissue were found to have altered stability. Replacement of HB10 with aspartic acid increased stability while substitutions at B28 and/or B29 were either comparable to insulin or had decreased stability.
D N, Brems, P L, Brown, C, Bryant, R E, Chance, L K, Green, H B, Long, A A, Miller, R, Millican, J E, Shields, B H, Frank   +9 more
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Amino acid derived 1,4‐dialkyl substituted imidazolones

Peptide Science, 2010
AbstractA general method for synthesis of 1,4‐substituted imidazolones from amino acids on solid support or in solution has been developed. Amino acid derived 3‐Boc‐(1,3)‐oxazinane (Box) protected amino aldehyde building blocks were coupled through urea bonds to the amino terminal of dipeptides or amino acids.
Diness, Frederik, Meldal, Morten Peter
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FLAVI: An Amino Acid Substitution Model for Flaviviruses

Journal of Molecular Evolution, 2020
Amino acid substitution models represent substitution rates among amino acids during the evolution. The models play an important role in analyzing protein sequences, especially inferring phylogenies. The rapid evolution of flaviviruses is expanding the threat in public health.
Thu Kim Le, Le Sy Vinh
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Asymmetric synthesis of ß-amino acids and α-substituted β-amino acids

Chem. Soc. Rev., 1996
This review is intended to give a brief summary of some of the more recent developments in the synthesis of p-amino acids and asubstituted amino acids. The first part is concerned with an overview of the naturally occurring compounds containing p-amino acids. The second part summarises results on the synthesis of natural and unnatural p-amino acids, by
Cardillo G., Tomasini C.
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Infuenza-specific Amino Acid Substitution Model

2009 International Conference on Knowledge and Systems Engineering, 2009
Amino acid substitution model is a crucial component in protein sequence comparative systems such as protein sequence similarity searching, protein sequence alignment, and protein phylogenetic analysis. Although several general amino acid substitution models have been estimated from large protein databases, they might not be appropriate for analyzing ...
Dang Cao Cuong, Le Si Quang, Le Sy Vinh
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