Characterization of blood-brain barrier L-arginine uptake using in situ brain perfusions in a female mouse model [PDF]
Fluids and Barriers of the CNSBackground L-arginine is a critical determinant of central nervous system (CNS) function through nitric oxide (NO) production. Its uptake from plasma into brain is dependent on carrier-mediated transport across the blood-brain barrier (BBB).
Olivia C. Milam +7 more
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Identification of transport systems involved in eflornithine delivery across the blood-brain barrier
Frontiers in Drug Delivery, 2023 Human African Trypanosomiasis (HAT) is a neglected parasitic disease that continues to persist in sub-Saharan Africa. It is fatal if untreated. The first stage of the disease is associated with the presence of the parasite in the periphery and the second
Christopher P. Watson +2 more
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Cells, 2021 L-Arginine, a semi-essential amino acid, was shown to delay dysfunction of motor neurons and to prolong the lifespan, upon analysis of transgenic mouse models of amyotrophic lateral sclerosis (ALS).
Sana Latif, Young-Sook Kang
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Frontiers in Bioengineering and Biotechnology, 2023 We investigated the optimum co-culture ratio with the highest biological nitrogen removal rate, revealing that chemical oxygen demand, total nitrogen (TN), and ammoniacal nitrogen (NH3-N) removal was increased in the Chlorella pyrenoidosa and Yarrowia ...
Yuming Zhong +6 more
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Relació estructura-funció en la familia de transportadors d'aminoàcids heteromultimèrics identificació d'una nova farnjlia de transportadors lisosomals [PDF]
, 2000 [cat] ANTECEDENTS El coneixement de Ies diferents activitats de transport d'aminoàcids prové de l'anàlisi del transport d'aquests en cèl.lules o vesícules de membrana provinents del teixit que es vol analitzar.
Estévez Povedano, Raúl
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Systems biology of the qa gene cluster in Neurospora crassa. [PDF]
PLoS ONE, 2011 An ensemble of genetic networks that describe how the model fungal system, Neurospora crassa, utilizes quinic acid (QA) as a sole carbon source has been identified previously.
Xiaojia Tang +10 more
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L-arginine attenuates Interleukin-1β (IL-1β) induced Nuclear Factor Kappa-Beta (NF-κB) activation in Caco-2 cells. [PDF]
PLoS ONE, 2017 BACKGROUND:Specific nutrients like L-arginine (L-Arg) ameliorate intestinal inflammation, however the exact mechanisms of this effect are unclear. We hypothesized the anti-inflammatory effects of L-Arg require active transport and metabolism by inducible
Qinghe Meng +3 more
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Use of membrane vesicles to estimate the numbers of system y+ and system L amino acid transporters in human erythrocytes [PDF]
Biochemical Journal, 1991 We have used equilibrium values for L-leucine and L-lysine uptake by right-side-out vesicles to estimate the membrane abundance (sites/cell) of Na(+)-dependent amino acid transport systems L and y+ in human erythrocytes. All of the intravesicular space was accessible to L-leucine, as judged by comparisons with uridine uptake via the equilibrative ...
C M, Tse +3 more
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A mutation in amino acid permease AAP6 reduces the amino acid content of the Arabidopsis sieve elements but leaves aphid herbivores unaffected [PDF]
, 2010 The aim of this study was to investigate the role of the amino acid permease gene AAP6 in regulating phloem amino acid composition and then to determine the effects of this altered diet on aphid performance.
Newbury, H. J. +6 more
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JMIR Research Protocols, 2023 BackgroundFatigue is a strong predictor of negative health outcomes in older adults. Kynurenine, a metabolite of tryptophan, is strongly associated with fatigue.
Ronna N Robbins +4 more
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