Results 31 to 40 of about 248,141 (296)

Obligatory amino acid exchange via systems bo,+-like and y+L-like. A tertiary active transport mechanism for renal reabsorption of cystine and dibasic amino acids.

The Journal of biological chemistry, 1996
Mutations in the rBAT gene cause type I cystinuria, a common inherited aminoaciduria of cystine and dibasic amino acids due to their defective renal and intestinal reabsorption (Calonge, M. J., Gasparini, P., Chillarón, J., Chillón, M., Gallucci, M., Rousaud, F., Zelante, L., Testar, X., Dallapiccola, B., Di Silverio, F., Barceló, P., Estivill, X ...
J, Chillarón, R, Estévez, C, Mora, C A, Wagner, H, Suessbrich, F, Lang, J L, Gelpí, X, Testar, A E, Busch, A, Zorzano, M, Palacín   +10 more
openaire   +3 more sources

Structure-Affinity Relationships of Substrates for the Neutral Amino Acid Transport System in Rabbit Ileum

The Journal of General Physiology, 1974
The apparent affinities of various amino acids for the neutral amino acid transport system in rabbit ileum were determined by measuring the inhibition of L-methionine-14C influx across the brush border membrane.
R. Preston, J. Schaeffer, P. Curran
semanticscholar   +1 more source

Cationic amino acid transport across the blood-brain barrier is mediated exclusively by system y⁺

American Journal of Physiology-Endocrinology and Metabolism, 2006
Cationic amino acid (CAA) transport is brought about by two families of proteins that are found in various tissues: Cat (CAA transporter), referred to as system y+, and Bat [broad-scope amino acid (AA) transporter], which comprises systems b0,+, B0,+, and y+L.
Robyn L, O'Kane, Juan R, Viña, Ian, Simpson, Rosa, Zaragozá, Ashwini, Mokashi, Richard A, Hawkins   +5 more
openaire   +3 more sources

Cloning and functional expression of a cDNA from rat jejunal epithelium encoding a protein (4F2hc) with system y+L amino acid transport activity [PDF]

Biochemical Journal, 1998
Two different protein families, designated CAT (cationic amino acid transporter) and BAT (broad-specificity amino acid transporter) mediate the plasma membrane transport of cationic amino acids in animal cells. CAT transporters have 12-14 transmembrane domains and are selective for cationic amino acids.
S Y, Yao, W R, Muzyka, J F, Elliott, C I, Cheeseman, J D, Young   +4 more
openaire   +2 more sources

Transport of proteins into mitochondria [PDF]

, 1985
Translocational intermediates of precursor proteins of ATPase F1β subunit and cytochrome c1 across mitochondrial membranes were analyzed using two different approaches, transport at low temperature and transport after binding of precursor proteins to ...
Schleyer, Manfred, Neupert, Walter
core   +1 more source

Effect of oxygen tension on the amino acid utilisation of human embryonic stem cells

, 2014
Background/aims: human embryonic stem cells (hESCs) are a potential source of cells for treatment of many degenerative diseases, but in culture have a propensity to spontaneously differentiate, possibly due to suboptimal conditions. Culture at low oxygen
Christensen, David R., David R. Christensen, Calder, Philip C., Houghton, Franchesca D., Philip C. Calder, Franchesca D. Houghton   +5 more
core   +1 more source

Evidence for a close link between the thyroid hormone transport system and the aromatic amino acid transport system T in erythrocytes.

Journal of Biological Chemistry, 1990
The transport of [125I]triiodothyronine ([125I]T3) and [3H]tryptophan ([3H]Trp) by washed rat erythrocytes was studied at 25 degrees C in the presence of leucine in order to block the neutral amino acid transport system L.
Y. Zhou, Michel Samson, J. Osty, J. Francon, J. Blondeau   +4 more
semanticscholar   +1 more source

Amino acid transporter genes are essential for FLO11-dependent and FLO11-independent biofilm formation and invasive growth in saccharomyces cerevisiae

, 2012
Amino acids can induce yeast cell adhesion but how amino acids are sensed and signal the modulation of the FLO adhesion genes is not clear. We discovered that the budding yeast Saccharomyces cerevisiae CEN.PK evolved invasive growth ability under ...
Eckhard Boles, Sefa Alizadeh, Eckhard Boles (148580), Henrik Devitt Møller (148562), Møller, Henrik Devitt, Doreen Ochmann (148576), Møller, Henrik D., Gresham, David, Ochmann, Doreen, Doreen Ochmann, Torbensen, Rasmus, Birgitte Regenberg, Rasmus Torbensen, David Gresham (148568), Boles, Eckhard, Regenberg, Birgitte, Henrik Devitt Møller, Birgitte Regenberg (24433), Rasmus Torbensen (148554), Sefa Alizadeh (148573), Alizadeh, Sefa, David Gresham   +21 more
core   +1 more source

Structure and function of amino acid and peptide transport proteins [PDF]

, 2008
All living cells are enclosed by biological membranes that separate the interior cytoplasm from the outer environment. Composed of a phospholipid bilayer with embedded proteins biological membranes act as insulators and filters.
Casagrande, Fabio
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source