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Experimental & Molecular Medicine, 2020 AbstractOver 90 years ago, Otto Warburg’s seminal discovery of aerobic glycolysis established metabolic reprogramming as one of the first distinguishing characteristics of cancer1. The field of cancer metabolism subsequently revealed additional metabolic alterations in cancer by focusing on central carbon metabolism, including the citric acid cycle and
Elizabeth L. Lieu +3 more
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Prevalent Intrinsic Emission from Nonaromatic Amino Acids and Poly(Amino Acids) [PDF]
arXiv, 2017 Nonaromatic amino acids are generally believed to be nonemissive, owing to their lack of apparently remarkable conjugation within individual molecules. Here we report the intrinsic visible emission of nonaromatic amino acids and poly(amino acids) in concentrated solutions and solid powders.
Xiaohong Chen +5 more
arxiv +2 more sources
Metabolism of Amino Acids in Cancer
Frontiers in Cell and Developmental Biology, 2021 Metabolic reprogramming has been widely recognized as a hallmark of malignancy. The uptake and metabolism of amino acids are aberrantly upregulated in many cancers that display addiction to particular amino acids.
Zhen Wei +4 more
semanticscholar +1 more source
Amino Acids and Inherited Amino Acid-Related Disorders [PDF]
Journal of Nutrition and Metabolism, 2018 Amino acids perform multiple essential physiological roles in humans, and accordingly, their importance to health has been the subject of extensive attention. In this special issue of the Journal of Nutrition and Metabolism, we focus on the various inborn errors of amino acid metabolism, their diagnostic challenges, new treatment approaches, and recent
Ina Knerr +5 more
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Photosynthesis of amino acids [PDF]
Biochimica et Biophysica Acta (BBA) - General Subjects, 1964 Abstract Methods have been developed for performing dual tracer experiments with 15 N and 14 C on the photosynthesis and biosynthesis of amino acids in Chlorella pyrenoidosa . These methods involved the development of apparatus for maintaining algae in a condition of steady-state photosynthesis, including amino acid synthesis, and of adding ...
Bassham, J.A., Kirk, Martha.
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The Journal of Poultry Science, 2007 The influence of varying leucine and fetal calf serum (FCS) concentrations in the culture medium on protein synthesis and degradation of chicken embryo myoblasts was examined.
Mai Oki +3 more
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Molecular & Cellular Proteomics, 2002 Quantitative proteomics has traditionally been performed by two-dimensional gel electrophoresis, but recently, mass spectrometric methods based on stable isotope quantitation have shown great promise for the simultaneous and automated identification and ...
Shao-En Ong +6 more
semanticscholar +1 more source
Fluorescent Reporters and Biosensors for Probing the Dynamic Behavior of Protein Kinases
Proteomes, 2015 Probing the dynamic activities of protein kinases in real-time in living cells constitutes a major challenge that requires specific and sensitive tools tailored to meet the particular demands associated with cellular imaging.
Juan A. González-Vera, May C. Morris
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ChemInform, 1998 AbstractFor Abstract see ChemInform Abstract in Full Text.
Mark G. Moloney +2 more
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Learning the Hydrophilic, Hydrophobic and Aromatic Character of Amino Acids from their Interfacial Thermal Conductance in Water [PDF]
, 2021 In this study, the thermal relaxation of the 20 naturally occurring amino-acids in water is investigated using transient non-equilibrium molecular-dynamics simulations. By modeling the thermal relaxation process, the relaxation times of the amino-acids in water occurs over a timescale covering 2-5 ps.
arxiv +1 more source