Results 1 to 10 of about 7,358,220 (254)

Distances and classification of amino acids for different protein secondary structures [PDF]

open access: yesPRE 67,051927 (2003), 2002
Window profiles of amino acids in protein sequences are taken as a description of the amino acid environment. The relative entropy or Kullback-Leibler distance derived from profiles is used as a measure of dissimilarity for comparison of amino acids and secondary structure conformations.
J. Garnier   +10 more
arxiv   +4 more sources

A thermodynamic basis for prebiotic amino acid synthesis and the nature of the first genetic code [PDF]

open access: yes, 2009
Of the twenty amino acids used in proteins, ten were formed in Miller's atmospheric discharge experiments. The two other major proposed sources of prebiotic amino acid synthesis include formation in hydrothermal vents and delivery to Earth via meteorites.
Chakrabarti S.   +2 more
arxiv   +3 more sources

Is Amino-Acid Homochirality Due To Asymmetric Photolysis In Space? [PDF]

open access: yesarXiv, 1999
Amino acids occurring in proteins are, with rare exceptions, exclusively of the L-configuration. Among the many scenarios put forward to explain the origin of this chiral homogeneity (i.e., homochirality), one involves the asymmetric photolysis of amino acids present in space, triggered by circularly polarized UV radiation.
Cerf, C., Jorissen, A.
arxiv   +3 more sources

Prevalent Intrinsic Emission from Nonaromatic Amino Acids and Poly(Amino Acids) [PDF]

open access: yesarXiv, 2017
Nonaromatic amino acids are generally believed to be nonemissive, owing to their lack of apparently remarkable conjugation within individual molecules. Here we report the intrinsic visible emission of nonaromatic amino acids and poly(amino acids) in concentrated solutions and solid powders.
Xiaohong Chen   +5 more
arxiv   +2 more sources

Metabolism of Amino Acids in Cancer

open access: yesFrontiers in Cell and Developmental Biology, 2021
Metabolic reprogramming has been widely recognized as a hallmark of malignancy. The uptake and metabolism of amino acids are aberrantly upregulated in many cancers that display addiction to particular amino acids.
Zhen Wei   +4 more
semanticscholar   +1 more source

Amino acids in cancer

open access: yesExperimental and Molecular Medicine, 2020
Over 90 years ago, Otto Warburg’s seminal discovery of aerobic glycolysis established metabolic reprogramming as one of the first distinguishing characteristics of cancer1.
Elizabeth L. Lieu   +3 more
semanticscholar   +1 more source

Influence of Leucine on Protein Metabolism of Chicken Embryo Myoblasts is Modulated by Varying Serum Concentrations in the Medium

open access: yesThe Journal of Poultry Science, 2007
The influence of varying leucine and fetal calf serum (FCS) concentrations in the culture medium on protein synthesis and degradation of chicken embryo myoblasts was examined.
Mai Oki   +3 more
doaj   +1 more source

Stable Isotope Labeling by Amino Acids in Cell Culture, SILAC, as a Simple and Accurate Approach to Expression Proteomics*

open access: yesMolecular & Cellular Proteomics, 2002
Quantitative proteomics has traditionally been performed by two-dimensional gel electrophoresis, but recently, mass spectrometric methods based on stable isotope quantitation have shown great promise for the simultaneous and automated identification and ...
Shao-En Ong   +6 more
semanticscholar   +1 more source

Fluorescent Reporters and Biosensors for Probing the Dynamic Behavior of Protein Kinases

open access: yesProteomes, 2015
Probing the dynamic activities of protein kinases in real-time in living cells constitutes a major challenge that requires specific and sensitive tools tailored to meet the particular demands associated with cellular imaging.
Juan A. González-Vera, May C. Morris
doaj   +1 more source

Synthesis and reactivity of 4-oxo-5-trimethylsilanyl derived α-amino acids [PDF]

open access: yes, 2015
A Lewis-acid promoted one-carbon homologation of an aspartic acid semialdehyde with trimethylsilyldiazomethane has led to the efficient synthesis of two silicon-containing α-amino acids.
Adamczyk   +70 more
core   +1 more source

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