Results 101 to 110 of about 148,306 (298)

Branched-chain amino acid metabolism in cancer

Current Opinion in Clinical Nutrition & Metabolic Care, 2018
The current review aims to provide an update on the recent biomedical interest in oncogenic branched-chain amino acid (BCAA) metabolism, and discusses the advantages of using BCAAs and expression of BCAA-related enzymes in the treatment and diagnosis of cancers.An accumulating body of evidence demonstrates that BCAAs are essential nutrients for cancer ...
Ananieva, Elitsa A., Wilkinson, Adam C.
openaire   +3 more sources

Engineering Strategies for Stable and Long‐Life Alkaline Zinc‐Based Flow Batteries

Advanced Functional Materials, EarlyView.
Alkaline zinc‐based flow batteries face persistent challenges from unstable zinc deposition, including dendrite growth, passivation, corrosion, and hydrogen evolution, which severely limit cycling stability. Current research addresses these issues through coordinated electrode structuring, electrolyte regulation, and membrane design to control zinc ...
Yuran Bai, Xiaoyu Huo, Xin Long, Enkang Fu, Xusong Gong, Lei Wei, Liang An   +6 more
wiley   +1 more source

Prospective association between plasma amino acids and three Multimorbidity patterns in older adults

Scientific Reports
The role of metabolomic profiling on different multimorbidity patterns remains unknown. This study aims to assess the prospective relationship between plasma concentrations of amino acids and three different multimorbidity patterns: musculoskeletal and ...
Grace Velapatiño-Gamarra, Alberto Lana, Humberto Yévenes-Briones, Juan Cárdenas-Valladolid, José R. Banegas, Fernando Rodríguez-Artalejo, Esther López-García, Francisco Félix Caballero   +7 more
doaj   +1 more source

Menkes Maple Syrup Urine Disease: Treatment

Pediatric Neurology Briefs, 1991
Five patients with maple syrup urine disease were treated intra-venously with branched-chain amino acid-free solution of amino acids during nine episodes of acute illness and are reported from the Children’s Hospital of Philadelphia, PA.
J Gordon Millichap
doaj   +1 more source

Global Metabolic Shifts in Age and Alzheimer's Disease Mouse Brains Pivot at NAD+/NADH Redox Sites. [PDF]

, 2019
Age and Alzheimer's disease (AD) share some common features such as cognitive impairments, memory loss, metabolic disturbances, bioenergetic deficits, and inflammation.
Brewer, Gregory J, Dong, Yue
core  

Plasmids in the aphid endosymbiont Buchnera aphidicola with the smallest genomes. A puzzling evolutionary story.

, 2006
Buchnera aphidicola, the primary endosymbiont of aphids, has undergone important genomic and biochemical changes as an adaptation to intracellular life.
Gil, Rosario, Latorre, Amparo, Perez-Brocal, Vicente, Sabater-Muñoz, Beatriz, Silva, Francisco J   +4 more
core   +1 more source

Establishing a Model Precursor System: Over a Decade of Research on Carbon Dots from the Citric Acid‐Urea System

Advanced Functional Materials, EarlyView.
The citric acid/urea (CA‐Urea) precursor system offers a versatile, scalable route to carbon dots with tunable luminescence and multifunctionality. Mechanistic insights into precursor chemistry and reaction parameters have enabled doping, surface modification, and hybridization strategies, yielding CDs for luminescent devices, sensing, catalysis ...
Yupeng Liu, Zhiqi Cai, Xiangxin Sun, Hanyi Zhang, Yiming Hao, Jun Wu, Zekun Yan, Xue Wu, Yiqi Liang, Liming Wang, Songnan Qu   +10 more
wiley   +1 more source

An assessment of organic solvent based equilibrium partitioning methods for predicting the bioconcentration behavior of perfluorinated sulfonic acids, carboxylic acids, and sulfonamides [PDF]

, 2009
SPARC, KOWWIN, and ALOGPS octanol-water partitioning (log K~ow~) and distribution (log D) constants were calculated for all C~1~ through C~8~ and the straight chain C~9~ through C~15~ perfluoroalkyl sulfonic acids (PFSAs) and carboxylic acids (PFCAs ...
Kaya Forest, Sierra Rayne
core   +1 more source

Metformin promotes lifespan through mitohormesis via the peroxiredoxin PRDX-2 [PDF]

, 2014
The antiglycemic drug metformin, widely prescribed as first-line treatment of type II diabetes mellitus, has lifespan-extending properties. Precisely how this is achieved remains unclear.
Billen, Johan, Braeckman, Bart, De Haes, Wouter, Depuydt, Geert, Frooninckx, Lotte, Schoofs, Liliane, Smolders, Arne, Temmerman, Liesbet, Van Assche, Roel   +8 more
core   +1 more source

Toward Stable Multivalent Metal Batteries: Understanding the Interfacial Chemistry for Magnesium and Calcium Metal Anodes

Advanced Functional Materials, EarlyView.
Interphase chemistry governs the stability of multivalent metal batteries. We summarize state‐of‐the‐art developments in calcium and magnesium metal batteries by focusing on the correlation among electrolytes, interphase layers, and the electrochemical performance of corresponding metal anodes.
Huijun Lin, Qi Meng, Juncai Long, Chuheng Cao, Zheng‐Long Xu   +4 more
wiley   +1 more source