Results 11 to 20 of about 8,648 (155)

Synthetic Diversity and Catalytic Mechanism of Peptide Dendrimers

CHIMIA, 2005
Peptide dendrimers composed of alternating sequences of natural amino acids and branching diamino acids are investigated as synthetic enzyme models.
Estelle Delort, Tamis Darbre, Jean-Louis Reymond   +2 more
doaj   +1 more source

A straightforward approach towards combined α-amino and α-hydroxy acids based on Passerini reactions

Beilstein Journal of Organic Chemistry, 2011
Complex amino acids with an α-acyloxycarbonyl functionality in the side chain are easily available through epoxide opening by chelated enolates and subsequent oxidation/Passerini reaction. This protocol works with both, aldehyde and ketone intermediates,
Ameer F. Zahoor, Sarah Thies, Uli Kazmaier   +2 more
doaj   +1 more source

The origin of biomolecular asymmetry – Insights from cometary and meteoritic matter

BIO Web of Conferences, 2014
The chemistry of life is purely stereospecific. The fundamental biopolymers – proteins and nucleic acids – are intrinsically chiral due to their molecular building blocks, namely L-amino acids and D-sugars.
Meinert C., Meierhenrich U.J., Nahon L., Hoffmann S.V., le Sergeant d’Hendecourt L.   +4 more
doaj   +1 more source

α,γ‐Diamino Acids: Asymmetric Synthesis of New Constrained 6‐Amino‐3‐azabicyclo[3.2.1]octane‐6‐carboxylic Acids. [PDF]

ChemInform, 2006
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
F. Caputo, C. Cattaneo, F. Clerici, M.L. Gelmi, S. Pellegrino   +4 more
openaire   +2 more sources

R₂²(8) motifs in Aminopyrimidine sulfonate/carboxylate interactions: Crystal structures of pyrimethaminium benzenesulfonate monohydrate (2:2:1) and 2-amino-4,6-dimethylpyrimidinium sulfosalicylate dihydrate (4:2:2)

Chemistry Central Journal, 2007
Background Pyrimethamine [2,4-diamino-5-(p-chlorophenyl)-6-ethylpyrimidine] is an antifolate drug used in anti-malarial chemotherapy. Pyrimidine and aminopyrimidine derivatives are biologically important compounds owing to their natural occurrence as ...
Muthiah Packianathan, Balasubramani Kasthuri, Lynch Daniel E   +2 more
doaj   +1 more source

STEREOSELECTIVE FORMATION OF α,α-DIAMINO ACID RESIDUE BY THE ADDITION OF l-α-AMINO ACID TO α-IMINO ACID [PDF]

Chemistry Letters, 1981
Abstract An addition of l-α-amino acids to β,β-dibromo-α-imino acids proceeded to give the corresponding optically active α,α-diamino acid derivatives. A several conversions of the products are also described.
Chung-gi Shin, Hisao Ohmatsu, Yoshiaki Sato, Juji Yoshimura   +3 more
openaire   +1 more source

Structures of the K35 and K15 capsular polysaccharides of Acinetobacter baumannii LUH5535 and LUH5554 containing amino and diamino uronic acids [PDF]

Carbohydrate Research, 2017
Capsular polysaccharides were isolated from A. baumannii LUH5535 (K35 CPS) and LUH5554 (K15 CPS) and studied by 1D and 2D 1H and 13C NMR spectroscopy. The CPSs were found to consist of linear tetrasaccharide repeats (K units) containing 2-acetamido-2-deoxy-d-galacturonic acid (K35) or 2,3-diacetamido-2,3-deoxy-d-glucuronic acid (K15) and 2,4 ...
Shashkov, Alexander, Liu, Bin, Kenyon, Johanna, Popova, Anastasiya, Shneider, Mikhail, Senchenkova, Sof'ya, Arbatsky, Nikolay, Miroshnikov, Konstantin, Wang, Lei, Knirel, Yuriy   +9 more
openaire   +3 more sources

Molecular Mobility of N‐Acetylgalactosamine‐Modified Cyclodextrins on a Polyrotaxane for Highly Efficient Liver Targeting of Antibody Chimeras and Genome‐Editing Ribonucleoproteins

Advanced Science, EarlyView.
Monovalent N‐acetylgalactosamine (GalNAc)‐modified polyrotaxane enables efficient liver targeting by utilizing ligand mobility. The sliding and rotating cyclic components i.e., cyclodextrin in the polyrotaxane dynamically cluster GalNAc moieties, thereby mimicking trivalent interactions with asialoglycoprotein receptors.
Toru Taharabaru, Keiichi Motoyama, Yuting Wen, Zhongxing Zhang, Xuehao Tian, Jun Li, Taishi Higashi   +6 more
wiley   +1 more source

Architecture‐Engineered Semi‐Crystalline Microporous Polymer Membranes for Precise Molecular Separation

Advanced Science, EarlyView.
Guided by a Random Forest model, a π–π‐driven ordered stacking strategy deploys functionally distinct substructures to restrict chain segment motion and increase free volume, while preserving the intermolecular interactions that maintain structural integrity.
Zi‐Meng Xu, Hao Zhuo, Song‐Hui Zhi, Xiao‐Feng Zhong, Pan‐Pan Zhang, Si‐Yuan Yang, Wen‐Yong Yang, Guang‐Yong Shen, Ya‐Zhao Li, Yi Li, Ming Xue   +10 more
wiley   +1 more source

Identification and theoretical study of the regioselectivity of the synthesis reaction of an α-heterocyclic α-amino ester

Eclética Química
The interest of amino acids no longer needs to be demonstrated, given the involvement of these compounds in various fields, both as basic elements of peptide and protein structures and as independent entities. We report the regioselective synthesis of an
Mohammed El Mesky, Hicham Zgueni, Mohamed Jabha, Youssef Youssefi, Nabil Amri, M’barek Azdouz, Ahmad Oubair, Driss Chebabe, Mohamed Azrour, El Houssine Mabrouk   +9 more
doaj   +1 more source