Results 61 to 70 of about 6,089,688 (338)

Age-related changes of muscle and plasma amino acids in healthy children

, 2010
The aim of the study was to explore if changes in muscle and plasma amino acid concentrations developed during growth and differed from levels seen in adults.
Andersson, Kerstin,, Wernerman, Jan,, Hammarqvist, Folke,, Angsten, Gertrud,, Meurling, Staffan,   +4 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Enhancing essential amino acid bioavailability of soy protein through Streptococcus thermophilus ST4 supplementation

Frontiers in Microbiology
BackgroundSoy protein is a popular plant-based protein source, but is nutritionally limited by its incomplete essential amino acid profile and lower bioavailability relative to animal proteins.
David Agus Setiawan Wibisono, Chiou-Yeong Saw, Bo-Long Jian, Der-Kai Lau, Der-Kai Lau, Wei-Jen Chen, Hui-Fang Chu, Cheng-Yen Liu, Chi-Fai Chau   +8 more
doaj   +1 more source

Structural analyses combined with small-angle X-ray scattering reveals that the retention of heme is critical for maintaining the structure of horseradish peroxidase under denaturing conditions.

, 2018
We analyzed the structure of horseradish peroxidase (HRP) under denaturing conditions of 9 M urea or 6 M guanidine hydrochloride (GdnHCl). Far-UV circular dichroism (CD) spectra indicated the existence of native-like secondary structure of holo-HRP in 9 ...
Jang, D.S, Choi, K.Y., Jin, K.S, Cha, H.J   +3 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Amino acids and central fatigue

, 2001
There is an increasing interest in the mechanisms behind central fatigue, particularly in relation to changes in brain monoamine metabolism and the influence of specific amino acids on fatigue.
Blomstrand, Eva,, Blomstrand, E
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Evolutionary proteomics identifies amino acids essential for ligand-binding of the cytokinin receptor CHASE domain

BMC Evolutionary Biology, 2007
BackgroundIn plants the hormone cytokinin is perceived by members of a small cytokinin receptor family, which are hybrid sensor histidine kinases.
A. Heyl, Klaas Wulfetange, Birgit Pils, Nicolaj D. Nielsen, G. Romanov, T. Schmülling   +5 more
semanticscholar   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Considerations on amino acid patterns in the natural felid diet: a review

Frontiers in Veterinary Science
Amino acids are essential for the growth, development, and reproduction of carnivores. This literature review summarizes the amino acid patterns of different raw diets including whole prey, body tissue and muscle for felids under human care.
Mengmeng Sun, Annelies De Cuyper, Ellen S. Dierenfeld, Geert P. J. Janssens   +3 more
doaj   +1 more source