Results 51 to 60 of about 749,065 (306)
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Italian Journal of Animal Science, 2014 A three-week trial was conducted to determine the effect of lowering dietary protein level (DPL) with optimal amino acid (AA) profile on growth performance, blood metabolites, and relative weights of abdominal fat and internal organs in broiler chickens ...
Elmutaz Atta Awad +4 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Frontiers in MicrobiologyBackgroundSoy protein is a popular plant-based protein source, but is nutritionally limited by its incomplete essential amino acid profile and lower bioavailability relative to animal proteins.
David Agus Setiawan Wibisono +8 more
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Amino acid uptake in Arabidopsis [PDF]
, 2008 Nitrogen (N) is essential for all living organisms and is considered to be the limiting factor for plant growth in many ecosystems. Although generally believed to rely on mineral N to fulfill their N needs, plants have also been found to access organic N
Svennerstam, Henrik
core
Essential amino acids composition of fermentation products.
, 2021 Essential amino acids composition of fermentation products.
Jiazhou Li (8409465) +6 more
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Essential Amino Acids for Muscle Protein Accretion
, 2010 SUMMARY: THE STIMULATION OF MUSCLE PROTEIN SYNTHESIS IS RELIANT ON THE ADEQUATE AVAILABILITY OF AMINO ACID (AA) PRECURSORS. THE INCREASE IN CIRCULATING AA CONCENTRATIONS IN THE BLOOD SERVES AS A SIGNAL TO INITIATE SYNTHETIC PROCESSES.
Wolfe, RR +4 more
core +1 more source
High glycine concentration increases collagen synthesis by articular chondrocytes in vitro: acute glycine deficiency could be an important cause of osteoarthritis [PDF]
, 2018 Collagen synthesis is severely diminished in osteoarthritis; thus, enhancing it may help the regeneration of cartilage. This requires large amounts of glycine, proline and lysine.
de Paz-Lugo, Patricia +6 more
core +1 more source