Results 51 to 60 of about 753,565 (262)

Considerations on amino acid patterns in the natural felid diet: a review

Frontiers in Veterinary Science
Amino acids are essential for the growth, development, and reproduction of carnivores. This literature review summarizes the amino acid patterns of different raw diets including whole prey, body tissue and muscle for felids under human care.
Mengmeng Sun, Annelies De Cuyper, Ellen S. Dierenfeld, Geert P. J. Janssens   +3 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Effects of Different Drying Temperature on Quality Components of Ziziphi Spinosae Folium Insect Tea

Shipin gongye ke-ji, 2023
A series of methods such as the high performance liquid chromatography and amino acid analyzer were used to study the effects of different drying temperatures (60, 75, 90 and 105 ℃) on the protein, amino acids, fatty acids and other quality components of
Dongyin YUAN, Lixiang WEN, Fen ZHANG, Shuqiong OU, Jiaxian CHEN, Jingru PENG, Yuan ZHAO, Shouhui HUANG, Yewei TAN   +8 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Essential Amino Acid Density

Nutrition Today, 2021
The essential amino acid (EAA) content of animal-based proteins contributes to their superior quality compared with plant-based proteins. Recently, there has been a growing trend toward plant-based meal patterns. However, the impact of adapting a primarily plant-based meal pattern in the context of US Department of Agriculture’ Healthy Eating Patterns ...
Maya Fussell, Allison Contillo, Heidi Druehl, Nancy R. Rodriguez   +3 more
openaire   +2 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Amino acid release patterns of growing pig diets formulated with different dietary protein sources

Journal of Applied Animal Research, 2019
This study elucidated the dynamics of AA release in low-protein growing pig diets formulated with different protein sources. Four protein sources including soybean meal (SM), corn gluten meal (CGM), fish meal (FM) and fermented soybean meal (FSM) were ...
Abedin Abdallah, Jin Wang, Evera Elemba, Abdul-Halim Abubakari, Qingzhen Zhong, Zewei Sun   +5 more
doaj   +1 more source