Results 21 to 30 of about 7,755,658 (385)

Role of amino acid transporters in amino acid sensing [PDF]

open access: yesThe American Journal of Clinical Nutrition, 2014
Amino acid (AA) transporters may act as sensors, as well as carriers, of tissue nutrient supplies. This review considers recent advances in our understanding of the AA-sensing functions of AA transporters in both epithelial and nonepithelial cells.
openaire   +3 more sources

Dietary L-glutamate modulates intestinal mucosal immunity of juvenile hybrid striped bass (Morone saxatilis ♀ × Morone chrysops ♂)

open access: yesFrontiers in Immunology
IntroductionL-Glutamate is a conditionally essential amino acid, meaning it can become essential under specific conditions, like stress or disease. It is an abundant intracellular amino acid crucial in immune responses.
Karina L. Hissen   +4 more
doaj   +1 more source

Different domains cooperate to target the human ribosomal L7a protein to the nucleus and to the nucleoli. [PDF]

open access: yes, 1997
The human ribosomal protein L7a is a component of the major ribosomal subunit. We transiently expressed in HeLa cells L7a-β-galactosidase fusion proteins and studied their subcellular localization by indirect immunofluorescence staining with anti-β ...
Giulia RUSSO   +2 more
core   +1 more source

Physiology of the Amino Acids [PDF]

open access: yesScience, 1942
We have followed the amino acids from their entrance into the alimentary tract in the form of food proteins through the successive steps of digestion, absorption into the blood stream and passage from the blood stream into the tissues, where they are concentrated by some unknown mechanism to many times their concentration in the blood plasma.
openaire   +2 more sources

Puromycin Sensitivity of Ribosomal Label after Incorporation of 14C-Labelled Amino Acids into Isolated Mitochondria from Neurospora crassa [PDF]

open access: yes, 1969
Radioactive amino acids were incorporated into isolated mitochondria from Neurospora crassa. Then the mitochondrial ribosomes were isolated and submitted to density gradient centrifugation. A preferential labelling of polysomes was observed.
Dingman C. W.   +8 more
core   +2 more sources

Amino acid metabolism in health and disease

open access: yesSignal Transduction and Targeted Therapy, 2023
Amino acids are the building blocks of protein synthesis. They are structural elements and energy sources of cells necessary for normal cell growth, differentiation and function.
Zhe-Nan Ling   +5 more
semanticscholar   +1 more source

Amino acid neurotransmitters in the CNS

open access: yesFEBS Letters, 1986
D‐Aspartate exchange, defined as amino acid‐stimulated D‐[3H]aspartate efflux, was investigated in a preparation of rat brain synaptosomes. The efflux of radiolabelled D‐aspartate was found to be enhanced by micromolar concentrations of externally added D‐ and L‐aspartate, L‐glutamate, L‐cysteate.and L‐cysteinesulphinate.
Erecińska, Maria, Troeger, Melody B.
openaire   +2 more sources

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

open access: yesFEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Functions and Signaling Pathways of Amino Acids in Intestinal Inflammation

open access: yesBioMed Research International, 2018
Intestine is always exposed to external environment and intestinal microorganism; thus it is more sensitive to dysfunction and dysbiosis, leading to intestinal inflammation, such as inflammatory bowel disease (IBD), irritable bowel syndrome (IBS), and ...
Fang He   +7 more
semanticscholar   +1 more source

RAD50 missense variants differentially affect the DNA damage response and mitotic progression

open access: yesFEBS Letters, EarlyView.
RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker   +9 more
wiley   +1 more source

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