Results 81 to 90 of about 7,358,369 (397)

Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells

open access: yesFEBS Letters, EarlyView.
Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga   +6 more
wiley   +1 more source

Branched-chain amino acids: physico-chemical properties, industrial synthesis and role in signaling, metabolism and energy production

open access: yesAmino Acids
Branched-chain amino acids (BCAAs)—leucine (Leu), isoleucine (Ile), and valine (Val)—are essential nutrients with significant roles in protein synthesis, metabolic regulation, and energy production.
Philipp Reifenberg, Aline Zimmer
doaj   +1 more source

Decomposition of Amino Acids in Water with Application to In-Situ Measurements of Enceladus, Europa and Other Hydrothermally Active Icy Ocean Worlds [PDF]

open access: yes, 2019
To test the potential of using amino acid abundances as a biosignature at icy ocean worlds, we investigate whether primordial amino acids (accreted or formed by early aqueous processes) could persist until the present time. By examining the decomposition kinetics of amino acids in aqueous solution based on existing laboratory rate data, we find that ...
arxiv   +1 more source

Amino acids: inhibitors or promoters of anaerobic biocorrosion of steels? [PDF]

open access: yes, 2007
Various authors have shown that some amino acids can act as corrosion inhibitors, which has generated an increasing interest in these compounds as substitutes to conventional corrosion inhibitors that are usually toxic [1,2].
Basséguy, Régine   +5 more
core   +5 more sources

Excitatory amino acids in synaptic transmission in the Schaffer collateral‐commissural pathway of the rat hippocampus.

open access: yesJournal of Physiology, 1983
1. The effects of excitatory amino acids and some antagonists applied by ionophoresis to stratum radiatum in the CA1 region of rat hippocampal slices were examined on the locally recorded field e.p.s.p.
G. Collingridge, S. J. Kehl, H. Mclennan
semanticscholar   +1 more source

The multiple roles of the NlpC_P60 peptidase family in mycobacteria – an underexplored target for antimicrobial drug discovery

open access: yesFEBS Letters, EarlyView.
The NlpC_P60 superfamily of peptidases is recognised by its key role in bacterial cell wall homeostasis. Recently, studies have also described the involvement of NlpC_P60‐like enzymes in bacterial competitive mechanisms and pathogenesis across several lineages.
Catharina dos Santos Silva   +1 more
wiley   +1 more source

Structural insights into the potential binding sites of Cathepsin D using molecular modelling techniques

open access: yesAmino Acids
Alzheimer’s disease (AD) is the most prevalent type of dementia caused by the accumulation of amyloid beta (Aβ) peptides. The extracellular deposition of Aβ peptides in human AD brain causes neuronal death.
Subodh A. Kamble   +5 more
doaj   +1 more source

Linguistic mechanism of the evolution of amino acid frequencies and genomic GC content [PDF]

open access: yesarXiv, 2006
Much information is stored in amino acid composition of protein and base composition of DNA. We simulated the evolution of amino acid frequencies and genomic GC content by a linguistic model. It is showed that the evolution of genetic code determines the evolution of amino acid frequencies and genomic GC content.
arxiv  

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

HECTD2 as a target for veratric acid in the regulation of ferroptosis in renal cell carcinoma

open access: yesAmino Acids
Function of HECTD2 in renal cell carcinoma malignant progression is undefined. Molecular mechanism behind anti-cancer effects of veratric acid (VA) from traditional Chinese medicine (TCM) is underexplored.
Dong Lv   +6 more
doaj   +1 more source

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