Synthesis of Trifluoromethylated Monoterpene Amino Alcohols [PDF]
For the first time, monoterpene trifluoromethylated β-hydroxy-benzyl-O-oximes were synthesized in 81–95% yields by nucleophilic addition of the Ruppert–Prakash reagent (TMSCF3) to the corresponding β-keto-benzyl-O-oximes based on (+)-nopinone ...
Polina A. Petrova +5 more
doaj +4 more sources
Amino Alcohols from the Ascidian Pseudodistoma sp. [PDF]
Seven new amino alcohol compounds, pseudoaminols A–G (1–7), were isolated from the ascidian Pseudodistoma sp. collected off the coast of Chuja-do, Korea.
Tae Hyung Won +6 more
doaj +6 more sources
Amino Alcohols as Potential Antibiotic and Antifungal Leads [PDF]
Five focused compound libraries (forty-nine compounds), based on prior studies in our laboratory were synthesized and screened for antibiotic and anti-fungal activity against S. aureus, E. coli, K. pneumoniae, P. aeruginosa, A. baumannii, C. albicans and
Jennifer R. Baker +7 more
doaj +7 more sources
Quinone-catalyzed oxidative deformylation: synthesis of imines from amino alcohols [PDF]
A new method for imine synthesis by way of quinone-catalyzed oxidative deformylation of 1,2-amino alcohols is reported. A wide range of readily accessible amino alcohols and primary amines can be reacted to provide N-protected imine products.
Xinyun Liu +4 more
doaj +4 more sources
Diastereoselective synthesis of vicinal amino alcohols [PDF]
The vicinal amino alcohol is a common motif in natural products and pharmaceuticals. Amino acids constitute a natural, inexpensive, and enantiopure choice of starting material for the synthesis of such functionalities. However, the matters concerning diastereoselectivity are not obvious.
Koskinen, Ari, Karjalainen, Oskari
openaire +7 more sources
Synthesis of Azetidine-Based Beta-Amino Alcohols [PDF]
Beta-amino alcohols are versatile chemicals used as scaffolds in medicinal chemistry and they are key factors for the efficacy of numerous pharmaceutical products.
Linda Supe
doaj +2 more sources
Highly Enantioselective Synthesis of β-Amino Alcohols [PDF]
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Métro, Thomas-Xavier +3 more
openaire +5 more sources
New Nitrogen, Sulfur-, and Selenium-Donating Ligands Derived from Chiral Pyridine Amino Alcohols. Synthesis and Catalytic Activity in Asymmetric Allylic Alkylation [PDF]
Although many chiral ligands for asymmetric catalysis have been developed, there is still a need for new structures allowing the modular approach. Recently, easy synthesis of chiral pyridine-containing β-amino alcohols has been elaborated by opening ...
Marzena Wosińska-Hrydczuk +1 more
doaj +2 more sources
Biosynthesis of Chiral Amino Alcohols via an Engineered Amine Dehydrogenase in E. coli [PDF]
Chiral amino alcohols are prevalent synthons in pharmaceuticals and synthetic bioactive compounds. The efficient synthesis of chiral amino alcohols using ammonia as the sole amino donor under mild conditions is highly desired and challenging in organic ...
Feifei Tong +13 more
doaj +2 more sources
Amino Alcohols from Eugenol as Potential Semisynthetic Insecticides: Chemical, Biological, and Computational Insights [PDF]
A series of β-amino alcohols were prepared by the reaction of eugenol epoxide with aliphatic and aromatic amine nucleophiles. The synthesized compounds were fully characterized and evaluated as potential insecticides through the assessment of their ...
Renato B. Pereira +9 more
doaj +2 more sources

