Synthesis of Trifluoromethylated Monoterpene Amino Alcohols [PDF]
Molecules, 2022 For the first time, monoterpene trifluoromethylated β-hydroxy-benzyl-O-oximes were synthesized in 81–95% yields by nucleophilic addition of the Ruppert–Prakash reagent (TMSCF3) to the corresponding β-keto-benzyl-O-oximes based on (+)-nopinone ...
Polina A. Petrova +5 more
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Amino Alcohols as Potential Antibiotic and Antifungal Leads [PDF]
Molecules, 2022 Five focused compound libraries (forty-nine compounds), based on prior studies in our laboratory were synthesized and screened for antibiotic and anti-fungal activity against S. aureus, E. coli, K. pneumoniae, P. aeruginosa, A. baumannii, C. albicans and
Jennifer R. Baker +7 more
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New Nitrogen, Sulfur-, and Selenium-Donating Ligands Derived from Chiral Pyridine Amino Alcohols. Synthesis and Catalytic Activity in Asymmetric Allylic Alkylation [PDF]
Molecules, 2021 Although many chiral ligands for asymmetric catalysis have been developed, there is still a need for new structures allowing the modular approach. Recently, easy synthesis of chiral pyridine-containing β-amino alcohols has been elaborated by opening ...
Marzena Wosińska-Hrydczuk +1 more
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Biosynthesis of Chiral Amino Alcohols via an Engineered Amine Dehydrogenase in E. coli [PDF]
Frontiers in Bioengineering and Biotechnology, 2022 Chiral amino alcohols are prevalent synthons in pharmaceuticals and synthetic bioactive compounds. The efficient synthesis of chiral amino alcohols using ammonia as the sole amino donor under mild conditions is highly desired and challenging in organic ...
Feifei Tong +13 more
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Amino Alcohols from the Ascidian Pseudodistoma sp. [PDF]
Marine Drugs, 2014 Seven new amino alcohol compounds, pseudoaminols A–G (1–7), were isolated from the ascidian Pseudodistoma sp. collected off the coast of Chuja-do, Korea.
Tae Hyung Won +6 more
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Multicomponent Domino Cyclization of Ethyl Trifluoropyruvate with Methyl Ketones and Amino Alcohols as A New Way to γ-Lactam Annulated Oxazacycles [PDF]
Molecules, 2023 A new route to bicyclic γ-lactams was found, which was proposed as a three-component cyclization of ethyl trifluoropyruvate with methyl ketones and 1,2-, 1,3-amino alcohols.
Marina V. Goryaeva +7 more
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Amino Alcohols from Eugenol as Potential Semisynthetic Insecticides: Chemical, Biological, and Computational Insights [PDF]
Molecules, 2021 A series of β-amino alcohols were prepared by the reaction of eugenol epoxide with aliphatic and aromatic amine nucleophiles. The synthesized compounds were fully characterized and evaluated as potential insecticides through the assessment of their ...
Renato B. Pereira +9 more
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Dual catalysis for enantioselective convergent synthesis of enantiopure vicinal amino alcohols [PDF]
Nature Communications, 2018 Chiral vicinal amino alcohols are found in many bioactive compounds and may serve as chiral ligands. Here, the authors report a photocatalytic enantioselective cross-coupling of nitrones with aromatic aldehydes with a chiral ligand-coordinated rare earth
Chen-Xi Ye +8 more
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Regioselective and Stereodivergent Synthesis of Enantiomerically Pure Vic-Diamines from Chiral β-Amino Alcohols with 2-Pyridyl and 6-(2,2′-Bipyridyl) Moieties [PDF]
Molecules, 2020 In this report, we describe the synthetic elaboration of the easily available enantiomerically pure β-amino alcohols. Attempted direct substitution of the hydroxyl group by azido-functionality in the Mitsunobu reaction with hydrazoic acid was ...
Marzena Wosińska-Hrydczuk +2 more
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Quinone-catalyzed oxidative deformylation: synthesis of imines from amino alcohols [PDF]
Beilstein Journal of Organic Chemistry, 2017 A new method for imine synthesis by way of quinone-catalyzed oxidative deformylation of 1,2-amino alcohols is reported. A wide range of readily accessible amino alcohols and primary amines can be reacted to provide N-protected imine products.
Xinyun Liu +4 more
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