Results 11 to 20 of about 58,506 (161)
Oxidative Lactamization of Amino Alcohols: An Overview [PDF]
Journal of Chemistry Letters, 2020 Lactams are essential functional groups in a number of pharmacologically and biologically active compounds. They are widely found in many natural products, marketed drugs, as well as in the base of polymeric structures (e.g., polyamides/Nylons).
Lakashima Sreerama +2 more
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Photoinduced β-fragmentation of aliphatic alcohol derivatives for forging C–C bonds
Nature Communications, 2022 Transformations of alcohols, which are ubiquitous in chemistry and are native functionalities in many natural products and bioactive molecules, are cornerstones of organic synthesis.
Yiman Gao +6 more
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Diastereoselective synthesis of vicinal amino alcohols [PDF]
Organic & Biomolecular Chemistry, 2012 The vicinal amino alcohol is a common motif in natural products and pharmaceuticals. Amino acids constitute a natural, inexpensive, and enantiopure choice of starting material for the synthesis of such functionalities. However, the matters concerning diastereoselectivity are not obvious.
Koskinen, Ari, Karjalainen, Oskari
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Cytotoxicity Studies of Eugenol Amino Alcohols Derivatives
Chemistry Proceedings, 2021 Eugenol is a phenylpropanoid displaying a wide range of biological activities. In this study, the cytotoxic activity of various β-amino alcohols derivatives from eugenol was evaluated in AGS (gastric cancer) and A549 (lung cancer) cell lines. The results
Cláudia Teixeira +7 more
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Hydrogen Bonding and Polymorphism of Amino Alcohol Salts with Quinaldinate: Structural Study
Molecules, 2022 Three amino alcohols, 3-amino-1-propanol (abbreviated as 3a1pOH), 2-amino-1-butanol (2a1bOH), and 2-amino-2-methyl-1-propanol (2a2m1pOH), were reacted with quinoline-2-carboxylic acid, known as quinaldinic acid.
Nina Podjed, Barbara Modec
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Synthesis of Azetidine-Based Beta-Amino Alcohols
Medical Sciences Forum, 2022 Beta-amino alcohols are versatile chemicals used as scaffolds in medicinal chemistry and they are key factors for the efficacy of numerous pharmaceutical products.
Linda Supe
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Synthesis of 2H-pyrroles via iron catalyzed dehydrogenative coupling and C–C bond cleavage
Green Synthesis and Catalysis, 2021 Iron catalyzed coupling of β-amino alcohols with allylic alcohols for the synthesis of 3,4-dihydro-2H-pyrrole derivatives has been developed. Mechanistic studies suggest that the reaction involves iron catalyzed dehydrogenative coupling and C–C bond ...
Suya Cui +7 more
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Molecules, 2011 In this study, we prepared oxizolidines through 1,3-bis(diphenylphosphino)-propane (DPPP)–catalyzed mixed double-Michael reactions of b-amino alcohols with electron-deficient acetylenes.
Yi Chiao Fan, Ohyun Kwon
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Heteroatom Chemistry, 2019 New epoxides, derivatives of pyridine, 2,2′-bipyridine, and 1,10-phenanthroline, were synthesized from the respective α-methylazaarenes. The obtained racemic 2-oxiranyl-azaarenes along with styrene oxide and trans-stilbene oxide were submitted to the ...
Marzena Wosińska-Hrydczuk +1 more
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Molecules, 2013 The palladium (II)-catalysed reactions of alkenols and aminoalkenols such as oxycarbonylations or bicyclisations are powerful methods for the construction of oxygen and nitrogen-containing heterocyclic compounds. This review highlights recent progress in
Jana Doháňošová, Tibor Gracza
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