Results 241 to 250 of about 1,291,699 (306)

Unraveling A4GALT Mechanism and Its Modulation With Adamantyl‐Galactosylceramide Analogues: Advancing Fabry Disease Therapeutic Strategies

Angewandte Chemie, EarlyView.
A 310‐helix‐mediated conformational switch promotes a front‐face SNi‐like catalysis by human A4GALT. Mechanism‐guided design identifies AdaGalCer as a selective modulator of globotriaosylceramide (Gb3) biosynthesis, opening a clear route toward new Fabry disease therapeutics.
Nicky de Koster, Òscar Vidal‐Gironès, Rowan de Graaf, Ken Kok, Lindsey T. Lelieveld, Jackelien Hoogervorst, Maria J. Ferraz, José Pablo Rivas‐Fernández, Rob F. Lammers, Herman S. Overkleeft, Johannes M. F. G. Aerts, Rolf G. Boot, Carme Rovira, Marta Artola   +13 more
wiley   +1 more source

Post-Translational Control of Nitrate Reductase Under Elevated CO₂ in <i>Solanum lycopersicum</i>: Carbon-Nitrogen Signaling and Photosynthetic Acclimation. [PDF]

Plants (Basel)
Sahoo A, Meena M.
europepmc   +1 more source

Adaptive Laboratory Evolution of the Non-Conventional Yeast <i>Pichia ethanolica</i> for Improved Molasses Utilization Reveals Multilevel Adaptive Remodeling. [PDF]

Microorganisms
Yang P, Fan Y, Hu B, Ren W, Shi C, Jiang Y, Li B, Zhang X, Liu H, Chen Z, Gong A.   +10 more
europepmc   +1 more source

Pre-exposure to UV-B irradiation induces antioxidant enzymes and mitigates <i>Fusarium acutatum</i> stress in shallot (<i>Allium cepa</i> L.). [PDF]

Plant Signal Behav
Doni F, Riani FM, Awal MA, Prismantoro D, Miranti M, Sawitri WD, Handayani VDS, Idris M, Nurulita S, Wibowo A, Widiastuti A.   +10 more
europepmc   +1 more source

Predicting food taste with bound-driven optimization. [PDF]

Curr Res Food Sci
Tagkopoulos P, Sfondilis D, Tagkopoulos I, Zohdi T.   +3 more
europepmc   +1 more source

Analysis of the Mechanisms of Rice <i>oszfp30</i> Mutant in Improving Forage-Quality-Related Traits Based on Transcriptome and Metabolome Analyses. [PDF]

Genes (Basel)
Dong C, Zhao R, Shang P, Jiang Y, He Y, Yan Y, Chen C.   +6 more
europepmc   +1 more source

Starter-Culture-Dependent Effects of <i>Lactiplantibacillus plantarum</i> and <i>Lactobacillus delbrueckii</i> subsp. <i>bulgaricus</i> Fermentation on Nutritional Quality, Flavor Characteristics and Metabolite Profiles of <i>Flammulina velutipes</i> Roots. [PDF]

Foods
Zhou H, Zhang M, Chen M, Zhang S, Wu Y, Nan H, Qu Z.   +6 more
europepmc   +1 more source

Quality characterization of fermented rice wines: A multivariate study on physicochemical indices, biogenic amines, volatile profiles, and sensory evaluation. [PDF]

Food Chem X
Yuan H, Zhao X, Yuan H, Tian Z, Xu Z, Xie T, Lou K.   +6 more
europepmc   +1 more source

Valorization of Miscanthus × giganteus hydrolysates into heme-enriched yeast biomass and extract using xylose-fermenting Saccharomyces cerevisiae. [PDF]

Bioresour Bioprocess
Jung SC, Oh H, Kim S, Singh S, Singh V, Kim SR, Lu T, Koh HG, Jin YS.   +8 more
europepmc   +1 more source

Comprehensive analysis of the effects of foliar application of the synthetic strigolactone analog GR24 during the growth period on postharvest quality and metabolic indicators of pak choi. [PDF]

Food Chem X
Ma Y, Cai Q, Wang C, Liu Y, Chang Y, Zhang J, Xie J.   +6 more
europepmc   +1 more source