Results 21 to 30 of about 840 (114)

The Formation of a Ternary Complex between Diphtheria Toxin, Aminoacyltransferase II, and Diphosphopyridine Nucleotide

Journal of Biological Chemistry, 1970
Abstract The formation of a ternary complex between diphtheria toxin, transferase II (the peptidyl transfer RNA translocation factor), and diphosphopyridine nucleotide has been demonstrated by ultracentrifugation analyses. The complex has a s20,w value of 6.8 S and a molecular weight of 114,000.
J, Everse, D A, Gardner, N O, Kaplan, W, Galasinski, K, Moldave   +4 more
openaire   +2 more sources

EFFECT OF ENZYMATIC TREATMENTS ON CARBOHYDRATE MATRICES TOWARDS HEALTHY GLUTEN FREE FOODS APPLICATION [PDF]

, 2017
Tesis por compendioStarch is the major energy reserve in plants, extensively present in many food and non-food applications, and is one of the most abundant carbohydrates in human diet.
Durá de Miguel, Ángela
core   +1 more source

Characterization of SyrC, an Aminoacyltransferase Shuttling Threonyl and Chlorothreonyl Residues in the Syringomycin Biosynthetic Assembly Line

Chemistry & Biology, 2007
Syringomycin, a lipopeptidolactone assembled from nine amino acid monomers by four enzymes, SyrB1, SyrB2, SyrC, and SyrE, is a cyclic nonribosomal peptide made by plant-associated Pseudomonas spp. This assembly is unusual because the terminal residue, 4-chlorothreonine, has been proposed to be added in trans since the ninth module of the megasynthetase
Singh, Gitanjali M., Vaillancourt, Frédéric H., Yin, Jun, Walsh, Christopher T.   +3 more
openaire   +2 more sources

Mutagenetic analysis of the biosynthetic pathway of tetramate bripiodionen bearing 3-(2H-pyran-2-ylidene)pyrrolidine-2,4-dione skeleton [PDF]

Peer ...
Cheng, Yijia, Deng, Hai, Hong, Li Li, Li, Mengjia, Lin, Hou Wen, Zang, Haixia, Zhou, Lin, Zhou, Yongjun   +7 more
core   +1 more source

On the molecular biology and evolution of plant parasitism by nematodes [PDF]

, 2016
Plant-parasitic nematodes (PPN) are among the most devastating plant pathogens. However, our understanding of how nematodes adapted to plant parasitism, and the molecular mechanisms that PPN use during infection is limited.
Noon, Jason Brett
core   +2 more sources

The Concise Guide to PHARMACOLOGY 2025/26: Enzymes

British Journal of Pharmacology, Volume 182, Issue S1, Page S307-S403, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander, Doriano Fabbro, Alasdair J. Gibb, Eamonn Kelly, Alistair A. Mathie, Chloe J. Peach, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Christopher Southan, Jamie A. Davies, Stephanie Annett, Detlev Boison, Kathryn Elisa Burns, Carmen Dessauer, Jürg Gertsch, Nuala Ann Helsby, Angelo A. Izzo, Rennolds Ostrom, Ester Pagano, Andreas Papapetropoulos, Nigel J. Pyne, Susan Pyne, Tracy Robson, Roland Seifert, Johannes‐Peter Stasch, Csaba Szabo, Mario van der Stelt, Albert van der Vliet, Val Watts, Szu Shen Wong   +31 more
wiley   +1 more source

Predicting Drug Targets in Human Cancers

Journal of Clinical Pharmacy and Therapeutics, Volume 2025, Issue 1, 2025.
Introduction A large amount of knowledge has accumulated regarding the pharmacology of most cancer types, including their side effects, and during the last decade, many novel agents have emerged, accompanied by increased costs for healthcare systems. Aim Artificial intelligence (AI) was applied in healthcare services, and the benefit of its use in the ...
David Calderón Guzmán, Norma Osnaya Brizuela, Armando Valenzuela Peraza, Maribel Ortiz Herrera, Diego E. Ortega Garcia, Hugo Juarez Olguin, Gerardo Barragán Mejía, Md Saquib Hasnain   +7 more
wiley   +1 more source

In Silico Identification and Characterization of Drug Targets in Streptococcus pneumoniae ATCC 700669 (Serotype 23F) by Subtractive Genomics

BioMed Research International, Volume 2024, Issue 1, 2024.
Streptococcus pneumoniae (S. pneumoniae) is an important pathogen worldwide that causes pneumococcal infections which are related to high rates of morbidity and mortality especially in young children, older adults, and immune‐compromised persons. Antibiotic resistance in S.
Tolossa Duguma, Hunduma Dinka, Shibiao Wan   +2 more
wiley   +1 more source

Characterization of the Biological Function of Dnmt2 in Drosophila melanogaster [PDF]

, 2013
Dnmt2 genes encode highly conserved and widely distributed RNA methyltransferases with poorly understood biological functions. Recently, it has been shown that Dnmt2-mediated tRNA methylation interfered with stress-induced tRNA fragmentation, which ...
Durdevic, Zeljko
core   +1 more source

tRNAs: Cellular Barcodes for Amino Acids [PDF]

, 2009
The role of tRNA in translating the genetic code has received considerable attention over the last 50 years, and we now know in great detail how particular amino acids are specifically selected and brought to the ribosome in response to the corresponding
Banerjee, Ranat, Chen, Shawn, Dare, Kiley, Gilreath, Marla, Ibba, Michael, Praetorius-Ibba, Mette, Raina, Medha, Reynolds, Noah M., Rogers, Theresa E., Roy, Hervé, Yadavalli, Srujana S.   +10 more
core   +1 more source