Results 1 to 10 of about 11,356 (158)

Epsilon aminocaproic acid (EACA) myopathy [PDF]

open access: yesPostgraduate Medical Journal, 1979
SummaryTwo female patients developed a severe, painful proximal myopathy after taking 18–30 g of epsilon-aminocaproic acid daily for 5 weeks. Marked elevations of serum aminotransferases, creatine kinase and aldolase levels were found and the first patient had electromyographic and muscle biopsy changes of an acute monophasic, necrotising myopathy at ...
A. M. Martin   +3 more
openaire   +3 more sources

Mussel‐Inspired Molecular Strategies for Fabricating Functional Materials With Underwater Adhesion and Self‐Healing Properties

open access: yesAdvanced Materials, EarlyView.
This review systematically examines the nanomechanical mechanisms of mussel‐inspired molecular interactions, primarily investigated by direct force measurement techniques such as surface forces apparatus and atomic force microscopy. The macroscopic adhesive and self‐healing performances of mussel‐inspired functional materials, including coacervates ...
Pan Huang, Hongjian Zhang, Hongbo Zeng
wiley   +1 more source

Hydrophobicity‐Controlled Self‐Assembly of Supramolecular Peptide Nanotubes in Water

open access: yesAngewandte Chemie, Volume 137, Issue 22, May 26, 2025.
Cyclic peptide–polymer conjugates, with varied length of hydrophobic alkyl linker group, are synthesized and assembled into nanotubes in water. Both synthetic studies and computational molecular dynamics simulations confirm the degree of hydrophobicity, providing an avenue to tune the length and dynamic nature of the peptide nanotubes. Abstract Polymer‐
Min Zeng   +4 more
wiley   +2 more sources

Suspended Tissue Open Microfluidic Patterning (STOMP)

open access: yesAdvanced Science, EarlyView.
Suspended Tissue Open Microfluidic Patterning (STOMP) is a method that enables precise spatial patterning within a single suspended tissue. By leveraging capillary pinning and open microfluidics, STOMP facilitates the creation of complex tissue interfaces such as diseased‐healthy boundaries and tissue‐tissue junctions. This method integrates mechanical
Amanda J. Haack   +22 more
wiley   +1 more source

Systemic allergic dermatitis to epsilon‐aminocaproic acid [PDF]

open access: yesContact Dermatitis, 2009
A 47-year-old Caucasian woman had a pruriginous dermatitis involving her axillary, infra-mammary and inguinal flexures, and the lateral aspects of her trunk. Confluent erythematous patches without epidermal detachment were observed, sparing the extremities and mucous membranes (Fig. 1). There were no systemic symptoms.
Cunha, D   +3 more
openaire   +3 more sources

A Human Engineered Heart Tissue‐Derived Lipotoxic Diabetic Cardiomyopathy Model Revealed Early Benefits of Empagliflozin

open access: yesAdvanced Science, EarlyView.
This study develops a human engineered heart tissue‐derived model of diabetic cardiomyopathy that accurately replicates the dynamic changes in the structural, contractile, and electrophysiological properties of the myocardium. Furthermore, this model is used to confirm the direct protective effects of empagliflozin on the heart through an SGLT2 off ...
Lin Cai   +9 more
wiley   +1 more source

Real‐Time Force Monitoring of Electrically Stimulated 3D‐Bioengineered Muscle Bioactuators Using Organic Sensors with Tunable Sensitivity

open access: yesAdvanced Intelligent Systems, EarlyView.
The integration of sensing elements in bioengineered actuators is key to obtain real‐time information about their performance and further control/automation. By coupling flexible organic field‐effect transistor to a skeletal muscle actuator we demonstrate the feasibility to record in real‐time its contractile behavior when stimulated by electrical ...
Stefano Lai   +5 more
wiley   +1 more source

Monolithic Biohybrid Flexure Mechanism Actuated by Bioengineered Skeletal Muscle Tissue

open access: yesAdvanced Intelligent Systems, EarlyView.
A scalable, monolithic biohybrid flexure mechanism is presented, integrating engineered skeletal muscle tissue with a soft, biocompatible, hollow silicone cylinder featuring dual pillars. Muscle contraction induces bending motion upon electrical stimulation, with performance governed by the structure's flexural rigidity.
Andrea Bartolucci   +13 more
wiley   +1 more source

Nanostructured drug delivery systems for posterior segment eye diseases: Strategies to defy ocular barriers

open access: yesBMEMat, EarlyView.
Efficient drug delivery to the posterior segment of the eye has long been a challenging issue due to the complex ocular barriers. The review focuses on the promise held by nanoplatforms for barrier penetration and the key mechanisms involved, also highlighting their advantages in achieving efficient drug delivery and superior treatment of PSEDs ...
Yifan Shen   +7 more
wiley   +1 more source

Contactless Conductivity Detection for Capillary Electrophoresis—Developments From 2020 to 2024

open access: yesELECTROPHORESIS, EarlyView.
ABSTRACT The review covering the development of capillary electrophoresis with capacitively coupled contactless conductivity detection from 2020 to 2024 is the latest in a series going back to 2004. The article considers applications employing conventional capillaries and planar lab‐on‐chip devices as well as fundamental and technical developments of ...
Peter C. Hauser, Pavel Kubáň
wiley   +1 more source

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