Enzymatic biotransformation of adipic acid to 6-aminocaproic acid and 1,6- hexamethylenediamine using engineered carboxylic acid reductases and aminotransferases [PDF]
Biocatalytic reduction of carboxylic acids is gaining importance for the production of polymer precursors and different chemicals. Carboxylic acid reductases (CARs) reduce carboxylic acids to aldehydes using ATP and NADPH as cofactors under mild ...
Evdokimova, Elena+6 more
core +1 more source
Reducing perioperative blood loss and allogeneic blood transfusion in patients undergoing major spine surgery [PDF]
▶ At present, individual techniques, including intraoperative acute normovolemic hemodilution, use of tranexamic acid, use of intrathecal morphine, proper positioning, and modification of operative techniques, seem most promising for reducing ...
Cheung, WY, Luk, KDK, Ng, KFJ, Tse, EYW
core +1 more source
Modular Living Muscle‐Based Biomimetic Actuators for Biosyncretic Robots
Inspired by human fusiform muscles, a modular double‐striped skeletal muscle tissue was designed, which has a maximum contractile force of 2.92 ± 0.07 mN, a maximum contractile strain of 28% and good electrical stimulation response characteristics (up to 10 Hz).
Lianchao Yang+7 more
wiley +1 more source
Inducing emesis in Australian dogs and cats: agents, adverse effects and antiemetic administration
Objective To describe the agents used by Australian veterinarians in inducing emesis in dogs and cats, adverse effects and antiemetic administration. Methods An anonymous online mixed‐methods survey incorporating closed and open‐ended questions was distributed to Australian veterinarians via e‐newsletters and social media between April and June 2024 ...
J Tsitonakis, E Hall, A Quain
wiley +1 more source
Hemostatic effects of tranexamic acid in elective thoracic aortic surgery: A prospective, randomized, double-blind, placebo-controlled study [PDF]
Objective: We studied the hemostatic effects of tranexamic acid in patients undergoing elective surgery involving the thoracic aorta. Methods: In a double-blind, randomized fashion, 60 consecutive patients were assigned to two treatment groups: 30 ...
Calori, Giliola+5 more
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ABSTRACT Background Von Willebrand disease (VWD) is an inherited bleeding disorder caused by deficient or dysfunctional von Willebrand factor (VWF). VWF replacement therapy is indicated in VWD management. Methods This systematic review was conducted to evaluate all available evidence of the efficacy, safety, dosing and consumption of pasteurized plasma‐
Carmen Escuriola Ettingshausen+6 more
wiley +1 more source
Various aspects of thrombolysis and fibrinolysis [PDF]
The author has described modern thrombolytic therapy of arterial and venous thrombosis and emboli by therapeutic fibrinolysis and other drugs also methods and effects of local and parenteral application of fibrinolysin preparations, dosage, control ...
Szirmai, E.
core +1 more source
Abstract figure legend Both ATP synthase and adenine nucleotide translocator (ANT) play key roles in mediating the permeability transition. The contribution of ANT becomes evident in the presence of atractylate (ATR) at pH 6.5, a condition that prevents ATP synthase channel activity. At pH 7.4, this effect is minimal, suggesting a critical role for ATP
Ludovica Tommasin+7 more
wiley +1 more source
Adhesive and degradative properties of human placental cytotrophoblast cells in vitro. [PDF]
Human fetal development depends on the embryo rapidly gaining access to the maternal circulation. The trophoblast cells that form the fetal portion of the human placenta have solved this problem by transiently exhibiting certain tumor-like properties ...
Cui, TY+7 more
core +3 more sources
Aprotinin reduces cardiac troponin I release and inhibits apoptosis of polymorphonuclear cells during off-pump coronary artery bypass surgery [PDF]
Objectives: In addition to blood-sparing effects, aprotinin may have cardioprotective and anti-inflammatory effects during cardiopulmonary bypass-assisted cardiac surgery.
Bert, C.+9 more
core +2 more sources