Results 31 to 40 of about 13,374 (236)

Plasmin inhibitors prevent leukocyte accumulation and remodeling events in the postischemic microvasculature. [PDF]

open access: yesPLoS ONE, 2011
Clinical trials revealed beneficial effects of the broad-spectrum serine protease inhibitor aprotinin on the prevention of ischemia-reperfusion (I/R) injury. The underlying mechanisms remained largely unclear.
Christoph A Reichel   +7 more
doaj   +1 more source

In vitro study of the spectrum antiviral activity of aliphatic acid toward the prototype coronavirus strain

open access: yesBiomedical and Biotechnology Research Journal, 2023
Background: The aim of this study was to perform an in vitro evaluation of the antiviral activity of several well-known organic substances against infectious bronchitis virus (IBV), the prototype strain of the coronavirus family.
Iryna V Dziublyk   +9 more
doaj   +1 more source

NMR spectroscopy of Cu(II) complexes with acrylamide and sodium acrylate copolymer and ω-amino acids

open access: yesЖурнал Белорусского государственного университета: Химия, 2021
Macromolecular complexes of acrylamide and sodium acrylate copolymer with microelements, including Cu(II), may form at preparation of crop protection and stimulation compositions, where the copolymer serves as an adhesive, water-retaining and film ...
Dmitry L. Kudryavsky   +4 more
doaj   +1 more source

Aprotinin may increase mortality in low and intermediate risk but not in high risk cardiac surgical patients compared to tranexamic acid and ε-aminocaproic acid - a meta-analysis of randomised and observational trials of over 30.000 patients [PDF]

open access: yes, 2013
Background: To compare the effect of aprotinin with the effect of lysine analogues (tranexamic acid and ε-aminocaproic acid) on early mortality in three subgroups of patients: low, intermediate and high risk of cardiac surgery.
Herrmann, Eva   +3 more
core   +3 more sources

Identification of a Novel Mutation in the SERPINE1 Gene Causing Clinical Hyperfibrinolysis in English Springer Spaniel Dogs. [PDF]

open access: yesJ Vet Intern Med
ABSTRACT Background A 7‐month‐old female spayed English Springer Spaniel (ESS) was evaluated for spontaneous hemoperitoneum. Hyperfibrinolysis was identified on thromboelastography. Hypothesis/Objectives To identify a genetic mutation causing congenital hyperfibrinolysis in the proband and evaluate the prevalence of the mutation in the ESS breed ...
Kilpatrick K   +7 more
europepmc   +2 more sources

Epsilon-aminocaproic acid for treatment of fibrinolysis during liver transplantation [PDF]

open access: yes, 1987
In 97 adult patients receiving liver transplants, the coagulation system was monitored by thrombelastography and by coagulation profile including PT; a PTT; platelet count; level of factors I, II, V, VII, VIII, IX, X, XI, and XII; fibrin degradation ...
Bontempo, FA   +6 more
core   +1 more source

Cytokine Adsorption onto the Modified Carbon Sorbent Surface in vitro in Peritonitis

open access: yesОбщая реаниматология, 2009
Objective: to evaluate the efficiency of cytokine sorption with carbon with a locally aminocaproic acid-modified surface from the plasma of patients with general purulent peritonitis. Materials and methods.
T. I. Dolgikh   +11 more
doaj   +1 more source

A general method for the synthesis of nanostructured large-surface-area materials through the self-assembly of functionalized nanoparticles [PDF]

open access: yes, 2005
A general synthetic method for the preparation of nanostructured materials with large surface area was developed by using nanoparticle building blocks. The preparation route involves the self-assembly of functionalized nanoparticles in a liquid-crystal ...
Antonelli   +23 more
core   +1 more source

Synthesis and Hemostatic Activity of New Amide Derivatives

open access: yesMolecules, 2022
Eight dipeptides containing antifibrinolytic agents (tranexamic acid, aminocaproic acid, 4-(aminomethyl)benzoic acid, and glycine—natural amino acids) were synthesized in a three-step process with good or very good yields.
Lukasz Banach   +9 more
doaj   +1 more source

Acquired hemophilia as the cause of life-threatening hemorrhage in a 94-year-old man: a case report

open access: yesJournal of Medical Case Reports, 2010
Introduction Acquired factor VIII deficiency is a rare entity that can lead to severe and life-threatening bleeding. We describe a case of severe bleeding from the tongue secondary to acquired hemophilia and discuss treatment options, including ...
Blanchard Elizabeth   +3 more
doaj   +1 more source

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