IN VITRO STUDY OF ANTI-INFLUENZA ACTIVITY OF PARA-AMINOBENZOIC ACID AND PROSPECTS OF NASAL DRUG DEVELOPMENT [PDF]
is a vitamin-like substance, para-aminobenzoic acid (PABA). The aim of this work is to study antiviral activity of para-aminobenzoic acid, ε-aminocaproic acid, and their mixture against influenza virus, to evaluate their cytotoxic effect and to calculate
Nefedova L. +8 more
doaj +1 more source
The paucity of multi-component compounds containing the non-steroidal anti-inflammatory drug (NSAID) S-(+)-ibuprofen (S-IBU) in combination with other drugs prompted the present study, which describes 1:1 salts of this active pharmaceutical ingredient ...
Hannah M. Frösler +3 more
doaj +1 more source
Plasmin inhibitors prevent leukocyte accumulation and remodeling events in the postischemic microvasculature. [PDF]
Clinical trials revealed beneficial effects of the broad-spectrum serine protease inhibitor aprotinin on the prevention of ischemia-reperfusion (I/R) injury. The underlying mechanisms remained largely unclear.
Christoph A Reichel +7 more
doaj +1 more source
NMR spectroscopy of Cu(II) complexes with acrylamide and sodium acrylate copolymer and ω-amino acids
Macromolecular complexes of acrylamide and sodium acrylate copolymer with microelements, including Cu(II), may form at preparation of crop protection and stimulation compositions, where the copolymer serves as an adhesive, water-retaining and film ...
Dmitry L. Kudryavsky +4 more
doaj +1 more source
Aprotinin may increase mortality in low and intermediate risk but not in high risk cardiac surgical patients compared to tranexamic acid and ε-aminocaproic acid - a meta-analysis of randomised and observational trials of over 30.000 patients [PDF]
Background: To compare the effect of aprotinin with the effect of lysine analogues (tranexamic acid and ε-aminocaproic acid) on early mortality in three subgroups of patients: low, intermediate and high risk of cardiac surgery.
Herrmann, Eva +3 more
core +3 more sources
Background: The aim of this study was to perform an in vitro evaluation of the antiviral activity of several well-known organic substances against infectious bronchitis virus (IBV), the prototype strain of the coronavirus family.
Iryna V Dziublyk +9 more
doaj +1 more source
Epsilon-aminocaproic acid for treatment of fibrinolysis during liver transplantation [PDF]
In 97 adult patients receiving liver transplants, the coagulation system was monitored by thrombelastography and by coagulation profile including PT; a PTT; platelet count; level of factors I, II, V, VII, VIII, IX, X, XI, and XII; fibrin degradation ...
Bontempo, FA +6 more
core +1 more source
Cytokine Adsorption onto the Modified Carbon Sorbent Surface in vitro in Peritonitis
Objective: to evaluate the efficiency of cytokine sorption with carbon with a locally aminocaproic acid-modified surface from the plasma of patients with general purulent peritonitis. Materials and methods.
T. I. Dolgikh +11 more
doaj +1 more source
Hereditary angioedema (HAE) in children and adolescents : a consensus on therapeutic strategies [PDF]
Hereditary angioedema due to C1 inhibitor (C1 esterase inhibitor) deficiency (types I and II HAE-C1-INH) is a rare disease that usually presents during childhood or adolescence with intermittent episodes of potentially life-threatening angioedema ...
Aberer, Werner +11 more
core +1 more source
High-Level Expression of Various Apolipoprotein (a) Isoforms by "Transferrinfection". The Role of Kringle IV Sequences in the Extracellular Association with Low-Density Lipoprotein [PDF]
Characterization of the assembly of lipoprotein(a) [Lp(a)] is of fundamental importance to understanding the biosynthesis and metabolism of this atherogenic lipoprotein. Since no established cell lines exist that express Lp(a) or apolipoprotein(a) [apo(a)
Azrolan N. +45 more
core +1 more source

