Results 81 to 90 of about 93,718 (253)

Prevention and management of febrile neutropenia in acute myeloid leukaemia and higher risk myelodysplastic syndrome: An international survey of current practice

British Journal of Haematology, EarlyView.
Summary Febrile neutropenia causes substantial morbidity in acute myeloid leukaemia and higher risk myelodysplastic syndrome. We aimed to describe current practice and priorities for clinical trials in the prevention and management of febrile neutropenia across Australia/New Zealand (ANZ), the United Kingdom (UK), Canada and Europe.
Aleece MacPhail, Justin Loke, Brett L. Houston, Claire Dendle, Andrea S. Henden, Robert Weinkove, Orla Morrissey, Dionysios Neofytos, Niccolò Buetti, Catriona Parker, Monica A. Slavin, Charles Craddock, Simon J. Stanworth, Zoe McQuilten, on behalf of the Australasian Leukaemia and Lymphoma Group Supportive Care Working Group and UK AML/Supportive Care Working Parties   +14 more
wiley   +1 more source

Patch Test Results With the European Baseline Series, 2021/2022—Joint European Results of the ESSCAA and the EBSB Working Groups of the ESCD, and the GEIDACC

Contact Dermatitis, EarlyView.
ABSTRACT Background Patch test results obtained with the European Baseline Series (EBS) in its current version serve both contact allergy surveillance and (re‐)assessing the diagnostic value of EBS allergens. Objectives To present results of current EBS patch testing, obtained in 59 departments in 14 European countries during 2021 and 2022.
Wolfgang Uter, S. Mark Wilkinson, Olivier Aerts, Andrea Bauer, Leopoldo Borrego, Richard Brans, Timo Buhl, Heinrich Dickel, Aleksandra Dugonik, Francesca Larese Filon, Ana Giménez Arnau, Cataldo Patruno, Györgyi Pónyai, Stamatis Gregoriou, Steffen Schubert, Dagmar Simon, Luca Stingeni, Skaidra Valiukevičienė, Elke Weisshaar, Thomas Werfel, Margarida Gonçalo, Marie‐L. A. Schuttelaar, ESSCAA and EBSB ESCD Working Groups, and the GEIDACC, Birger Kränke, Alexander Navarini, Philip Spring, Ulrike Beiteke, Cecilia Dietrich, Sibylle Schliemann, Detlef Becker, Swen Malte John, Nicola Wagner, Dimitra Koumaki, Maddalena Napolitano, Anna Belloni Fortina, Francesca Larese Filon, Rosella Gallo, Thomas Rustemeyer, Radoslaw Spiewak, Maja Kalac Pandurovic, Tanja Kmecl, Mojca Simončič Godnič, Nada Kecelj, Philippa Cousen, Ella Dendooven, Juan Francisco Silvestre Salvador, José Manuel Carrascosa Carrillo, Mónica Munera Campos, Esther Serra Baldrich, Gemma Melé‐Ninot, Cristina Barrabés Torrella, David Pesqué, María Antonia Pastor Nieto, Francisco Navarro Triviño, Inmaculada Ruiz Gonzales, Enrique Gómez de la Fuente, Susana Córdoba Guijarro, Francisco Javier Ortiz de Frutos, Fátima Tous Romero, Tatiana Sanz Sánchez, Pablo Chicharro Manso, Marta Andreu Barasoain, Marta Elosua González, Araceli Sánchez Gilo, Paloma Sánchez‐Pedreño Guillén, Pedro Mercader‐García, Carmen Paredes Suárez, María Elena Gatica Ortega, José Juan Pereyra Rodríguez, Javier Miquel Miquel, Mercedes Rodríguez Serna, Violeta Zaragoza Ninet, Ricardo González Pérez   +73 more
wiley   +1 more source

Microbiome‐Based Modeling of CAR‐T Therapy Response in Lymphoma: Insights From Shotgun Metagenomics Sequencing

European Journal of Haematology, EarlyView.
ABSTRACT The interplay between the commensal microbiota and the mammalian immune system may influence the outcomes of T cell‐driven cancer immunotherapies. However, clinical studies supporting microbiota‐based interventions in chimeric antigen receptor T‐cell (CAR‐T) therapy remain scarce.
Rafael Hernani, Eliseo Albert, Carlos Hernani‐Morales, Sheila Zúñiga, Ana Benzaquén, Laura González‐Castillo, Ester Colomer, Júlia Morell, José Francisco Català‐Senent, José Luis Piñana, Estela Giménez, Ariadna Pérez, Juan Carlos Hernández‐Boluda, Ignacio Arroyo, Marcos Rivada, Teresa Barber, Teresa Alemany, Enric Santacatalina, Pilar Rentero‐Garrido, María José Terol, Rafael Díaz, David Navarro, Carlos Solano   +22 more
wiley   +1 more source

Temporohyoid osteoarthropathy: Recurrence of clinical signs following standing partial ceratohyoidectomy in a Swiss Warmblood mare

Equine Veterinary Education, EarlyView.
Summary A 17‐year‐old Swiss Warmblood mare presented with signs of left‐sided facial nerve paralysis and was diagnosed with left‐sided temporohyoid osteoarthropathy (THO). A partial ceratohyoidectomy was performed in the standing, sedated mare to treat this condition.
J. Kuhlmann, E. Van der Vekens, C. Koch, M. D. Klopfenstein Bregger, M. de Preux, H. P. Brünisholz   +5 more
wiley   +1 more source

Lung organoids as a human system for Mycobacteria infection modeling and drug testing

The FEBS Journal, EarlyView.
Mycobacterial infections, including tuberculosis (TB) and infections by nontuberculous mycobacteria (NTM), are still public health issues. In 2023, TB caused 1.25 million deaths, while NTM remain a clinical challenge for patients with cystic fibrosis (CF).
Stephen Adonai Leon‐Icaza, Romain Vergé, Raoul Mazars, Laurence Berry, Céline Cougoule   +4 more
wiley   +1 more source

Plant‐produced encapsulin displays non‐typhoidal Salmonella enterica antigens and assembles into mosaic nanoparticles

The FEBS Journal, EarlyView.
This study investigates the potential of encapsulin as an antigen display platform for the development of a candidate Salmonella vaccine for poultry. Encapsulin constructs were transiently expressed in Nicotiana benthamiana where they accumulated to high levels.
Carly A. Charron, Angelo Kaldis, Shabnam Shamriz, Justin B. Renaud, Moussa S. Diarra, Christopher P. Garnham, Rima Menassa   +6 more
wiley   +1 more source

Aminoglycoside resistance profile and structural architecture of the aminoglycoside acetyltransferase AAC(6’)-Im

Microbial Cell, 2017
Aminoglycoside 6’-acetyltransferase-Im (AAC(6’)-Im) is the closest monofunctional homolog of the AAC(6’)-Ie acetyltransferase of the bifunctional enzyme AAC(6’)-Ie/APH(2”)-Ia.
Clyde A. Smith, Monolekha Bhattacharya, Marta Toth, Nichole K. Stewart, Sergei B. Vakulenko   +4 more
doaj   +1 more source

Toggled RNA Aptamers Against Aminoglycosides Allowing Facile Detection of Antibiotics Using Gold Nanoparticle Assays

Analytical Chemistry, 2012
We have used systematic evolution of ligands by exponential enrichment (SELEX) to isolate RNA aptamers against aminoglycoside antibiotics. The SELEX rounds were toggled against four pairs of aminoglycosides with the goal of isolating reagents that ...
N. Derbyshire, S. White, D. Bunka, Lei Song, S. Stead, J. Tarbin, M. Sharman, Dejian Zhou, P. Stockley   +8 more
semanticscholar   +1 more source

European Network for Optimization of Veterinary Antimicrobial Therapy (ENOVAT) 2025 guidelines for surgical antimicrobial prophylaxis in dogs and cats

Journal of Small Animal Practice, EarlyView.
Surgical antimicrobial prophylaxis involves the administration of antimicrobials to reduce the risk of a surgical site infection and represents a significant proportion of all antimicrobial use in cats and dogs. This evidence‐based, European Network for Optimization of Veterinary Antimicrobial Therapy guideline provides recommendations for both peri ...
F. Allerton, T. M. Sørensen, K. Scahill, J. E. Ruperez, F. Swinbourne, D. R. Verwilghen, M. C. Nolff, F. Foroutan, S. J. Baines, A. Vilen, L. Pelligand, E. M. Broens, P. L. Toutain, M. L. Brennan, T. Mooney, S. Clarke, J. E. Miles, J. L. Granick, Y. Winsborg, L. R. Jessen, J. S. Weese, on behalf of the European Network for Optimization of Veterinary Antimicrobial Therapy (ENOVAT) guidelines and the ESCMID Study Group for Veterinary Microbiology (ESGVM)   +21 more
wiley   +1 more source

Inhaled Antibiotics in Reanimatology: Problem State and Development Prospects (Review)

Общая реаниматология, 2018
Nosocomial pneumonia is the second most common nosocomial infection in critical care units and most common in ALV patients (9—27%). The purpose of this literature review is to discuss the latest domestic and foreign body of evidence concerning the use of
A. N. Kuzovlev, A. V. Grechko
doaj   +1 more source