Results 71 to 80 of about 71,389 (251)

Investigating the Cytotoxic Effects of Aminoglycosides on A549 Lung Cancer Cell Line [PDF]

Objective: The current study was carried out to evaluate the cytotoxicity activity of aminoglycosides, specifically amikacin and gentamicin, on human lung cancer cell lines.Methods: Cytotoxicity activity was evaluated on human cancer cell lines such as ...
Karthikeyan M, Praveen B M
core   +1 more source

Chicken‐linked multidrug‐resistant Campylobacter jejuni infections among Chinese children

iMetaOmics, EarlyView.
Campylobacter is a leading cause of pediatric diarrhea, but its genomic epidemiology and antimicrobial resistance in China remain poorly defined. We conducted genomic surveillance of 3492 children with diarrhea in two pediatric hospitals in Zhejiang Province in 2017, 2018, and 2021, combining culture, whole‐genome sequencing, and source‐attribution ...
Dongyan Shao, Yuchen Wu, Zhaoju Deng, Hanyu Wang, Can Cui, Jianzhong Shen, Julian Parkhill, Yang Wang, Rong Zhang, Dejun Liu   +9 more
wiley   +1 more source

Cyclic Peptide MV6, an Aminoglycoside Efficacy Enhancer Against Acinetobacter baumannii

Antibiotics
Background/Objectives: Acinetobacter baumannii is a globally emerging pathogen with widespread antimicrobial resistance driven by multiple mechanisms, such as altered expression of efflux pumps like AdeABC, placing it as a priority for research.
Natalia Roson-Calero, Jimmy Lucas, María A. Gomis-Font, Roger de Pedro-Jové, Antonio Oliver, Clara Ballesté-Delpierre, Jordi Vila   +6 more
doaj   +1 more source

Discrepant Urinary Findings Between Dipstick Protein and Sulfosalicylic Acid Test in a Patient With Hyaline Casts: A Case Report

Journal of Clinical Laboratory Analysis, EarlyView.
In this post‐transplant patient, increased hyaline casts with negative dipstick protein but positive SSA testing occurred during evolving acute kidney injury and resolved with renal recovery. This discordant urinalysis pattern may warrant confirmatory protein testing and correlation with serial renal function in patients at high risk of AKI.
Yifei Jia, Binquan Chu, Fengjun Chen, Xiangyu Zhu, Chen Hang, Xiaoling Yu, Jinpiao Lin   +6 more
wiley   +1 more source

Aminoglycoside heteroresistance in Enterobacter cloacae is driven by the cell envelope stress response

mBio
Enterobacter cloacae is a Gram-negative nosocomial pathogen of the ESKAPE (Enterococcus, Staphylococcus, Klebsiella, Acinetobacter, Pseudomonas, and Enterobacter spp.) priority group with increasing multi-drug resistance via the acquisition of resistance
Ana J. Choi, Daniel J. Bennison, Esha Kulkarni, Hibah Azar, Haoyu Sun, Hanqi Li, Jonathan Bradshaw, Hui Wen Yeap, Nicholas Lim, Vishwas Mishra, Anna Crespo-Puig, Ewurabena A. Mills, Frances Davies, Shiranee Sriskandan, Avinash R. Shenoy   +14 more
doaj   +1 more source

Comparative vestibulotoxicity of different aminoglycosides in the guinea pigs

, 2003
The histopathological alterations in the vestibule due to aminoglycosides are well defined. Although there are reports comparing the vestibulotoxic effects of the many aminoglycosides, this is the first study to compare the effects of the most commonly ...
Kalkandelen, S, Erdogan, F, Selimoglu, E, Erdoǧan, FAZLI, Selimoǧlu, Erol, Kalkandelen, Saadettin   +5 more
core   +1 more source

Effects of post‐hepatic portoenterostomy adjuvant therapy on liver transplantation in children with biliary atresia: A systematic review

JPGN Reports, EarlyView.
Abstract Objectives Biliary atresia (BA) is a cholangiopathy characterized by obstruction of the intrahepatic and extrahepatic bile ducts. Hepatic portoenterostomy (HPE) is the primary palliative treatment and there is still an urgent need to improve post‐HPE management.
Bianca Ferraz de Almeida Silva, Alice Palmeira Nascimento Cerqueira, Breno Oliveira Marques, Gabriela Garcia de Carvalho Laguna, Gabrielle dos Santos Aguiar, Luana Leal Gonzaga, Raquel Teles de Lacerda, Natalia Oliveira e Silva   +7 more
wiley   +1 more source

H-NS controls the susceptibility of Escherichia coli to aminoglycosides by interfering its uptake and efflux

Frontiers in Veterinary Science
H-NS is a histone-like nucleoid-structuring protein that regulates gene expressions, particularly acquired foreign genes, however, little is known about whether H-NS can modulate bacterial susceptibility by regulating its intrinsic genes. The hns-deleted
Qiuru Chen, Yulei Liang, Yanbin Dong, Junling Cui, Kun He, Xiaoyuan Ma, Jinfeng Zhao, Jinfeng Zhao, Yajun Zhai, Yajun Zhai, Li Yuan, Li Yuan, Li Yuan, Li Yuan   +13 more
doaj   +1 more source

Illuminating Streptomyces: Raman Spectroscopy for Antibiotic Detection and Monitoring

Journal of Raman Spectroscopy, EarlyView.
Raman spectroscopy provides a non‐destructive, label‐free approach for studying the chemical diversity of Streptomyces. This review presents its application from detection to chemical characterization of secondary metabolites and monitoring of biosynthetic processes.
Adéla Mikulová, Jan Bobek, Martin Kizovský, Markéta Benešová, Ota Samek, Pavlína Modlitbová, Zdeněk Pilát   +6 more
wiley   +1 more source

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source