Synthesis of Dehydrodipeptide and N-ethyl-dehydrodipeptide Derivatives with an α-Aminoisobutyric Acid Residue [PDF]
Several dipeptides with an N-benzyloxycarbonyl or an N-(tert-butyloxycarbonyl) α-aminoisobutyric acid residue and a β-hydroxyamino acid methyl ester were subjected to dehydration to form dehydrodipeptide derivatives.
Monteiro, Luís S. +2 more
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The cationic tetradecapeptide mastoparan as a privileged structure for drug discovery: Enhanced antimicrobial properties of mitoparan analogues modified at position-14 [PDF]
Mastoparan (MP) peptides, distributed in insect venoms, induce a local inflammatory response post envenomation. Most endogenous MPs share common structural elements within a tetradecapeptide sequence that adopts an amphipathic helix whilst traversing ...
Howl, John, Howl, Lewis, Jones, Sarah
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Background Primary hyperoxaluria type 2 is a rare monogenic disorder inherited in an autosomal recessive pattern. It results from the absence of the enzyme glyoxylate reductase/hydroxypyruvate reductase (GRHPR).
Jana Konkoľová +6 more
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A technique previously used to study placental transfer in pregnant rats, consisting of labeled tracer infusion through the left uterine artery, was employed to determine the utilization of lipogenic substrates by periuterine adipose tissue in the fed ...
M Palacín, M A Lasunción, E Herrera
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Rapid Optimization of Mcl-1 Inhibitors using Stapled Peptide Libraries Including Non-Natural Side Chains [PDF]
Alpha helices form a critical part of the binding interface for many protein-protein interactions, and chemically stabilized synthetic helical peptides can be effective inhibitors of such helix-mediated complexes.
Keating, Amy E. +3 more
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Genetic transformation of Fusarium avenaceum by Agrobacterium tumefaciens mediated transformation and the development of a USER-Brick vector construction system [PDF]
BACKGROUND: The plant pathogenic and saprophytic fungus Fusarium avenaceum causes considerable in-field and post-field losses worldwide due to its infections of a wide range of different crops.
Frandsen, Rasmus John Normand +5 more
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Hydroxy amino acids identified in the Murchison meteorite and their plausible formation pathways [PDF]
第7回極域科学シンポジウム:[OA] 南極隕石/はやぶさ12月1日(木)国立国語研究所 ...
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Brain-derived neurotrophic factor stimulates energy metabolism in developing cortical neurons. [PDF]
Brain-derived neurotrophic factor (BDNF) promotes the biochemical and morphological differentiation of selective populations of neurons during development.
Allaman, I. +4 more
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Altered Urinary Amino Acids in Children With Autism Spectrum Disorders
Autism spectrum disorders (ASD) affect 1% of children. Although there is no cure, early diagnosis and behavioral intervention can relieve the symptoms.
Aiping Liu +9 more
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EPR of Gamma Irradiated Nα -Monochloroacetyl-α-Aminoisobutyric Acid
Electron paramagnetic resonance of γ -irradiated single crystals of Nα -monochloroacetyl-α-aminoisobutyric acid were investigated at room temperature and 130 K. The paramagnetic center as attributed to the (CH3)2 ˙CCOOH radical.
Baskan, MH, Osmanoglu, S
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