Results 81 to 90 of about 8,541,382 (232)

5-aminolevulinic Acid and Surgical Margin Analysis in Calvarial Metastasis with Pericranium or Dural Extension: Technical Note

Brazilian Neurosurgery, 2020
Metastasis to the calvarium with direct pericranium or dural infiltration may be treated with radical surgical removal in selected cases. We describe microsurgical resection of calvarial metastases with fluorescence-guided technique using 5 ...
Erasmo Barros da Silva Junior, Joseph Franklin Chenisz da Silva, Maurício Coelho Neto, Marcella Santos Cavalcanti, Ricardo Ramina   +4 more
doaj   +1 more source

Methotrexate enhances 5-aminolevulinic acid-mediated photodynamic therapy-induced killing of human SCC4 cells by upregulation of coproporphyrinogen oxidase

, 2017
Background/Purpose: Topical 5-aminolevulinic acid-mediated photodynamic therapy (ALA-PDT) is effective for treatment of oral precancerous and cancerous lesions. This in vitro study tried to examine whether the SCC4 cell killing by ALA-PDT was enhanced by
Yang, Deng-Fu; Lee, Jeng-Woei; Chen, Hsin-Ming; Huang, Zheng; Hsu, Yih-Chih
core   +1 more source

Simulated daylight versus conventional PDT for mild to moderate actinic keratoses: A randomized controlled trial

Journal of the European Academy of Dermatology and Venereology, Volume 40, Issue 10, Page 1713-1720, October 2026.
This single‐centre, randomized controlled trial showed that simulated daylight photodynamic therapy (SDL‐PDT, n = 785 lesions) was less effective than conventional photodynamic therapy (C‐PDT, n = 673 lesions) in treating mild to moderate actinic keratoses with 1‐year clearance rates of 71.0% for SDL‐PDT versus 85.3% for C‐PDT (p < 0.001). However, SDL‐
Alexandra Sjöholm, Eva Backman, Maja Modin, Julia Fougelberg, Magdalena Claeson, John Paoli   +5 more
wiley   +1 more source

Treatment of sarcopenia and glucose intolerance through mitochondrial activation by 5-aminolevulinic acid

Scientific Reports, 2017
Recently, sarcopenia has attracted attention as therapeutic target because it constitutes a risk factor for metabolic and cardiovascular diseases.
Chikako Fujii, K. Miyashita, Masanori Mitsuishi, Masaaki Sato, K. Fujii, H. Inoue, Aika Hagiwara, Sho Endo, Asuka Uto, Masaki Ryuzaki, M. Nakajima, Tohru Tanaka, Masanori Tamaki, Ayako Muraki, T. Kawai, H. Itoh   +15 more
semanticscholar   +1 more source

Divergent roles of ent‐kaurene oxidase paralogs in rice momilactone biosynthesis

Journal of Integrative Plant Biology, Volume 68, Issue 10, Page 3776-3789, October 2026.
Rice contains a five‐gene tandem array of genes encoding members of the ent‐kaurene oxidase (KO) family, with OsKOL4 and OsKOL5 playing divergent roles in momilactone metabolism, but both acting in the production of antifungal and antibacterial phytoalexins, which are important for disease resistance.
Zhibiao Wang, Yiling Feng, Leiming You, Meimei Xu, Kristin Helwig, Riqing Li, Si Nian Char, Bing Yang, Reuben J. Peters   +8 more
wiley   +1 more source

EFFECT OF IRON NANO CHELATE ON ANTIOXIDANT ACTIVITY, POLYPHENOLIC CONTENTS AND ESSENTIAL OIL COMPOSITION OF PORTULACA OLERACEA L.

Acta Scientiarum Polonorum: Hortorum Cultus, 2018
In the present study, using ultrasonic irradiations, a novel nano-sized iron complex has been prepared from aminolevulinic acid and iron(III) nitrate under greenhouse conditions.
Vahid Tavallali
doaj   +1 more source

Relaxin‐2: Shaping the Proteomic Landscape of Skeletal Muscle Physiology, Glucose Trafficking, and Mitochondrial Function in Rat

The FASEB Journal, Volume 40, Issue 18, 30 September 2026.
Cardioprotective hormone relaxin‐2 showed relevant effects on rat skeletal muscle by altering proteins linked to muscle function, regeneration, differentiation, mitochondrial function, glucose metabolism, and structural integrity and organization. Specifically, relaxin‐2 reduced the expression of 95 proteins, increased 32, and elicited unique proteins ...
Xocas Vázquez‐Abuín, Lucía Gómez‐Cibeira, Javier García‐Seara, Pablo de la Fuente‐López, Carlos Minguito‐Carazo, Susana B. Bravo, Manuel Otero‐Santiago, Oreste Gualillo, José Ramón González‐Juanatey, Francisca Lago, Sandra Feijóo‐Bandín, Alana Aragón‐Herrera   +11 more
wiley   +1 more source

Efficacy and Safety of 5-Aminolevulinic Acid for Patients with Symptoms of Late-Onset Hypogonadism: A Preliminary Study

The World Journal of Men's Health, 2022
Purpose:Purpose: As the concept of late-onset hypogonadism (LOH) has gained increased attention, the treatment of eugonadal patients with LOH symptom has become a clinical problem.
Hiroki Koyasu, Shigeo Horie, Kazuhito Matsushita, Takeshi Ashizawa, Satoru Muto, Shuji Isotani, Tohru Tanaka, Motowo Nakajima, Akira Tsujimura   +8 more
doaj   +1 more source

Poly(L-histidine)-tagged 5-aminolevulinic acid prodrugs: new photosensitizing precursors of protoporphyrin IX for photodynamic colon cancer therapy

, 2012
Renjith P Johnson,1* Chung-Wook Chung,2* Young-Il Jeong,2 Dae Hwan Kang,2 Hongsuk Suh,3 Il Kim,11WCU Centre for Synthetic Polymer Bioconjugate Hybrid Materials, Department of Polymer Science and Engineering, Pusan National University, Pusan, 2National ...
Chung CW, Jeong YI, Renjith P. Johnson, Dae Hwan Kang, Kang DH, Chung-Wook Chung, Young-IL Jeong, Suh H, Kim I, Johnson RP, Hongsuk Suh, Kim   +11 more
core   +1 more source

Wavelength Dependency of Photodynamic Effects After Sensitization with 5-Aminolevulinic Acid In Vitro and In Vivo [PDF]

, 1995
A promising new therapeutic modality for skin cancer, administration of the heme precursor 5-aminolevulinic acid followed by light irradiation, is known as photodynamic therapy.
Abels, Christoph, Landthaler, Michael, Goetz, Alwin E., Karrer, Sigrid, Bäumler, Wolfgang, Szeimies, Rolf-Markus, Stinbach, Pia, Fritsch, Clemens, Goerz, Günter   +8 more
core   +1 more source