Results 121 to 130 of about 13,598,018 (237)
Immunity, Inflammation and Disease, Volume 14, Issue 11, November 2026.ABSTRACT Introduction Behçet's disease (BD) is a multisystem inflammatory vasculitis with clinical heterogeneity that may vary across ethnic groups within the same country. This study aimed to evaluate the influence of ethnicity on the clinical manifestations, immunogenic laboratory findings and disease course of BD by comparing Turkic and non‐Turkic ...
Shokufeh Sadeghi +7 more
wiley +1 more source
Journal of Environmental Quality, Volume 55, Issue 6, November/December 2026.Abstract Soils are increasingly receiving treated wastewater (TWW) to support crop production and protect natural resources. However, besides water, various inputs, such as soil nutrients (salts), organic carbon, and various contaminants of emerging concern, including antibiotics, antibiotic resistance genes, pharmaceutical compounds, heavy metals, and
Vasileios A. Tzanakakis +3 more
wiley +1 more source
, 1983 Udgivelsesdato: 1983-Apr-15The biosynthesis of small-intestinal aminopeptidase N (EC 3.4.11.2) was studied in a cell-free translation system derived from rabbit reticulocytes. When dog pancreatic microsomal fractions were present during translation, most
Danielsen, E M +2 more
core +1 more source
MedComm, Volume 7, Issue 11, November 2026.This 16‑week study assessed impact of dupilumab on skin barrier function in patients with moderate‑to‑severe atopic dermatitis (AD). Tape‑stripped stratum corneum samples for multi‑omic profiling, alongside transepidermal water loss measurements, were collected from lesional/non‑lesional AD skin and healthy controls at seven time points.
Taoming Liu +21 more
wiley +1 more source
Aminopeptidase N/CD13 Crosslinking Promotes the Activation and Membrane Expression of Integrin CD11b/CD18. [PDF]
Biomolecules, 2023 Díaz-Alvarez L +4 more
europepmc +1 more source
Targeted Protein Degradation: From Molecular Mechanisms to Emerging Therapeutic Strategies
MedComm, Volume 7, Issue 11, November 2026.Graphical overview of targeted protein degradation: mechanisms, molecular determinants, delivery strategies, and therapeutic development. This graphical abstract summarizes the major degradation pathways involved in targeted protein degradation, including the ubiquitin–proteasome system, endocytosis–lysosome pathway, and autophagy‐dependent degradation.
Huaijuan Guo +8 more
wiley +1 more source
Transcytosis of Aminopeptidase N in caco-2 cells is mediated by a Non-cytoplasmic Signal
, 1995 In Caco-2 cells, aminopeptidase N is transported to the apical membrane from the trans Golgi network by both the direct and the indirect pathway (Matter, K., Brauchbar, M., Bucher, K., and Hauri, H.-P. (1990) Cell 60, 429-437).
Vogel, L K, Norén, Ove, Sjöström, H
core +1 more source
Substrate‐Dependent Crosslinking by the Cytochrome P450 From Aminopyruvatide Biosynthesis
Angewandte Chemie, Volume 138, Issue 44, 26 October 2026.Substitutions in the aminopyruvatide precursor peptide altered the C─C linkage formed from a YLY motif by the P450 ApyO to a N─C linkage in a WLY motif. Moreover, constitutional isomers crosslinked by C─C and C─O linkages were formed from YYY or YWY motifs. ABSTRACT Cytochrome P450s catalyze an array of reactions including crosslinking of aromatic side
Chandrashekhar Padhi +6 more
wiley +2 more sources
Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future
Medicinal Research Reviews, Volume 46, Issue 6, Page 1574-1602, November 2026.ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley +1 more source