Results 1 to 10 of about 29,120 (189)

Genetic Parameters and Genome‐Wide Association Studies for Fertility and Reproduction Traits in U.S. Katahdin Sheep Based on the Single‐Step GBLUP Methodology

Journal of Animal Breeding and Genetics, EarlyView.
ABSTRACT Sheep production contributes to a secure and diverse food and fibre supply in the United States, with growing ethnic diversity strengthening demand. Katahdin is a composite hair‐type sheep breed developed in the United States that has become the most popular breed in many regions of the country and the first one to have genomic selection ...
Alejandra Toro Ospina, Ronald M. Lewis, Bradley A. Freking, Joan M. Burke, Thomas W. Murphy, Carrie S. Wilson, Luiz F. Brito   +6 more
wiley   +1 more source

Probiotic Stability and Antihypertensive Activity of Peptides in Aguamiel Syrup‐Fortified Milk Protein Fermented by Lacticasebacillus rhamnosus GG

eFood, Volume 7, Issue 4, August 2026.
This study evaluates the impact of aguamiel syrup on a synbiotic fermented dairy product, focusing on antihypertensive peptide release and Lacticaseibacillus rhamnosus GG survival. While metabolic parameters remained unchanged, aguamiel syrup enhanced bioactive peptide production and antihypertensive activity (45.3%), suggesting its potential as a ...
Olvera‐Rosales Laura Berenice, Leonel‐Enríquez Jorge Eduardo, Pérez‐Escalante Emmanuel, Castañeda‐Ovando Araceli, Contreras‐López Elizabeth, Cruz‐Guerrero Alma Elizabeth, González‐Olivares Luis Guillermo   +6 more
wiley   +1 more source

Salivary Extracellular Vesicles: Paradigm Shift in Liquid Biopsy Diagnostics

Journal of Extracellular Biology, Volume 5, Issue 7, July 2026.
ABSTRACT Extracellular vesicles (EVs), lipid bilayer nanoparticles released by virtually all cells, serve as essential messengers for intercellular communication. Due to their involvement in several pathophysiological processes, EVs have recently gained considerable attention as potentially diagnostic and prognostic biomarkers for various illnesses ...
Kwanele Xulu, Usri H. Ibrahim, Irene Mackraj, Carola Niesler   +3 more
wiley   +1 more source

Polymorphic positions 349 and 725 of the autoimmunity-protective allotype 10 of ER aminopeptidase 1 are key in determining its unique enzymatic properties

Frontiers in Immunology
IntroductionER aminopeptidase 1 (ERAP1) is a polymorphic intracellular aminopeptidase with key roles in antigen presentation and adaptive immune responses.
Galateia Georgaki, Galateia Georgaki, Anastasia Mpakali, Anastasia Mpakali, Myrto Trakada, Athanasios Papakyriakou, Efstratios Stratikos, Efstratios Stratikos   +7 more
doaj   +1 more source

Fecal Proteomics Suggest Potential Biomarkers for Non‐Alcoholic Fatty Liver Disease and Steatohepatitis

PROTEOMICS – Clinical Applications, Volume 20, Issue 4, July 2026.
ABSTRACT Background and aims Non‐alcoholic Fatty Liver Disease (NAFLD) affects about a quarter of the world's population. Liver biopsy remains the gold standard for diagnosing the progressive form of NAFLD called Non‐alcoholic Steatohepatitis (NASH) but it is invasive, prone to sampling errors and observer variability, and impractical for widespread ...
Anna Negroni, Luisa Pieroni, Noemi Fiaschini, Francesca Palone, Mariateresa Mancuso, Roberta Vitali   +5 more
wiley   +1 more source

Leucine Aminopeptidase from Xanthomonas oryzae pv. oryzae with Esterase Activity Toward Heroin: Biochemical and Catalytic Insights

Biomolecules
Heroin is a highly addictive drug that exerts its primary effects through activation of μ-opioid receptors. Its principal active metabolite, 6-monoacetylmorphine (6-MAM), significantly contributes to heroin’s neurological effects and acute toxicity ...
Hualing Li, Qi Hu, Nuo Xu, Xueting Shao, Yuxin Liu, Yuxin Hou, Binjie Wang, Jiye Wang, Jianzhuang Yao, Shurong Hou, Xiabin Chen   +10 more
doaj   +1 more source

Afforestation mitigates soil nitrogen limitation by enhancing mineralization and lowering denitrification in central China

Functional Ecology, Volume 40, Issue 7, Page 2114-2127, July 2026.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Afforestation has profoundly altered soil nitrogen (N) transformation, particularly the key processes governing soil organic N and inorganic N dynamics which determine soil N availability.
Xueyu Wang, Deping Zhai, Xin Quan, Chang Liao, Xiuxian Men, Xianxian Wang, Xiaoli Cheng   +6 more
wiley   +1 more source

From Angiotensin IV to Small Peptidemimetics Inhibiting Insulin-Regulated Aminopeptidase

Frontiers in Pharmacology, 2020
It was reported three decades ago that intracerebroventricular injection of angiotensin IV (Ang IV, Val-Tyr-Ile-His-Pro-Phe) improved memory and learning in the rat. There are several explanations for these positive effects of the hexapeptide and related
Mathias Hallberg, Mats Larhed
doaj   +1 more source

The litter C/N ratio governs the dual role of ectomycorrhizal fungi in decomposition and plant nutrition absorption

Functional Ecology, Volume 40, Issue 7, Page 2190-2202, July 2026.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Ectomycorrhizal fungi (EcMF) modulate litter decomposition and facilitate nutrient acquisition through the soil–mycorrhiza–plant pathway. Although litter chemistry has been considered an important factor affecting litter decomposition, how it regulates EcMF‐induced ...
Yan Mei, Qingyu Lan, Xin Liang, Qianwei Li, Guangyan Li, Qi Chen, Meng Lin, Yong Jia, Xingjun Tian   +8 more
wiley   +1 more source

On-target, dual aminopeptidase inhibition provides cross-species antimalarial activity

mBio
To combat the global burden of malaria, development of new drugs to replace or complement current therapies is urgently required. Here, we show that the compound MMV1557817 is a selective, nanomolar inhibitor of both Plasmodium falciparum and Plasmodium ...
Rebecca C. S. Edgar, Tess R. Malcolm, Ghizal Siddiqui, Carlo Giannangelo, Natalie A. Counihan, Matthew Challis, Sandra Duffy, Mrittika Chowdhury, Jutta Marfurt, Madeline Dans, Grennady Wirjanata, Rintis Noviyanti, Kajal Daware, Chathura D. Suraweera, Ric N. Price, Sergio Wittlin, Vicky M. Avery, Nyssa Drinkwater, Susan A. Charman, Darren J. Creek, Tania F. de Koning-Ward, Peter J. Scammells, Sheena McGowan   +22 more
doaj   +1 more source