Thermostable aminopeptidase from Pyrococcus horikoshii [PDF]
, 1999 From the genome sequence data of the thermophilic archaeon Pyrococcus horikoshii, an open reading frame was found which encodes a protein (332 amino acids) homologous with an endoglucanase from Clostridium thermocellum (42% identity), deblocking ...
Susumu Ando +11 more
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Study on preparation technology of low-phenylalanine perilla peptide
浙江大学学报. 农业与生命科学版, 2023 To enrich low-phenylalanine formula food for special medical purposes, this study used perilla defatted seed meal as the raw material to optimize the double enzymatic hydrolysis process through single factor and response surface analysis, while exploring
ZHANG Tianwei +4 more
doaj +1 more source
Laeverin/Aminopeptidase Q, a Novel Bestatin-sensitive Leucine Aminopeptidase Belonging to the M1 Family of Aminopeptidases [PDF]
Journal of Biological Chemistry, 2007 Laeverin/aminopeptidase Q (APQ) is a cell surface protein specifically expressed on human embryo-derived extravillous trophoblasts that invades the uterus during placentation. The cDNA cloning of Laeverin/APQ revealed that the sequence encodes a protein with 990 amino acid residues, and Laeverin/APQ contains the HEXXHX(18)E gluzincin motif, which is ...
Masato, Maruyama +6 more
openaire +2 more sources
METAP2 (methionyl aminopeptidase 2) [PDF]
, 2010 Review on METAP2 (methionyl aminopeptidase 2), with data on DNA, on the protein encoded, and where the gene is ...
RK Sharma +3 more
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, 2014 The full-length cDNA of four Ofapn aminopeptidases were cloned and sequenced from susceptible and resistant Ostrinia furnacalis strains. Four sequences were identified as APN because they shared the common structural features with APN from Lepidoptera ...
Wang, Z +6 more
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Sociobiology, 2018 Aminopeptidases are enzymes that cleave the N-terminal region of proteins and show structural conservation in prokaryotes and eukaryotes. We aimed to identify leucine-aminopeptidase A (LAP-A) orthologs in the genome of bee species with diff erent levels ...
Luana Bataglia +3 more
doaj +1 more source
Development of a Bestatin-SAHA Hybrid with Dual Inhibitory Activity against APN and HDAC
Molecules, 2020 With five histone deacetylase (HDAC) inhibitors approved for cancer treatment, proteolysis-targeting chimeras (PROTACs) for degradation of HDAC are emerging as an alternative strategy for HDAC-targeted therapeutic intervention.
Jiangying Cao +7 more
doaj +1 more source
Purification of P. c; chabaudi aminopeptidase, and antimalarial effects of the aminopeptidase inhibitor bestatin [PDF]
, 1997 The malarial parasite utilises amino acids drawn from the host haemoglobin for it's intraerythrocytic development. The endopeptidases described to date will only produce peptides from host haemoglobin.
Nnankya-Kitaka, Mary-Frances
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, 2019 Drug-induced liver injury (DILI) is a frequent cause of hepatic dysfunction as well as the single most frequent reason for removing approved medications from the market, and multispectral optoacoustic tomography (MSOT) is an emerging and noninvasive ...
Yong Huang +9 more
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(Journal of Industrial Microbiology & Biotechnology,31(6):273-277)Fusion of Bacillus stearothermophilus leucine aminopeptidase II with the raw starch-binding domain of Bacillus sp. strain TS-23 α-amylase generates a chimeric enzyme with enhanced thermostability and catalytic activity [PDF]
, 2014 Bacillus stearothermophilus leucine aminopeptidase 11 (LAPII) was fused at its C-terminal end with the raw-starch-binding domain of Bacillus sp. strain TS-23 alpha-amylase. The chimeric enzyme (LAPsbd), with an apparent molecular mass of approximately 61
Chi, M.C. +9 more
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