Results 31 to 40 of about 41,379 (247)
Purification of P. c; chabaudi aminopeptidase, and antimalarial effects of the aminopeptidase inhibitor bestatin [PDF]
, 1997 The malarial parasite utilises amino acids drawn from the host haemoglobin for it's intraerythrocytic development. The endopeptidases described to date will only produce peptides from host haemoglobin.
Nnankya-Kitaka, Mary-Frances
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IRAP Inhibitors: M1-Aminopeptidase Family Inspiration
Frontiers in Pharmacology, 2020 The insulin regulated aminopeptidase (IRAP) has been proposed as an important therapeutic target for indications including Alzheimer’s disease and immune disorders.
Nicholas Barlow, Philip E. Thompson
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Study on preparation technology of low-phenylalanine perilla peptide
浙江大学学报. 农业与生命科学版, 2023 To enrich low-phenylalanine formula food for special medical purposes, this study used perilla defatted seed meal as the raw material to optimize the double enzymatic hydrolysis process through single factor and response surface analysis, while exploring
ZHANG Tianwei +4 more
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Laeverin/Aminopeptidase Q, a Novel Bestatin-sensitive Leucine Aminopeptidase Belonging to the M1 Family of Aminopeptidases [PDF]
Journal of Biological Chemistry, 2007 Laeverin/aminopeptidase Q (APQ) is a cell surface protein specifically expressed on human embryo-derived extravillous trophoblasts that invades the uterus during placentation. The cDNA cloning of Laeverin/APQ revealed that the sequence encodes a protein with 990 amino acid residues, and Laeverin/APQ contains the HEXXHX(18)E gluzincin motif, which is ...
Masato, Maruyama +6 more
openaire +2 more sources
Sociobiology, 2018 Aminopeptidases are enzymes that cleave the N-terminal region of proteins and show structural conservation in prokaryotes and eukaryotes. We aimed to identify leucine-aminopeptidase A (LAP-A) orthologs in the genome of bee species with diff erent levels ...
Luana Bataglia +3 more
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Development of a Bestatin-SAHA Hybrid with Dual Inhibitory Activity against APN and HDAC
Molecules, 2020 With five histone deacetylase (HDAC) inhibitors approved for cancer treatment, proteolysis-targeting chimeras (PROTACs) for degradation of HDAC are emerging as an alternative strategy for HDAC-targeted therapeutic intervention.
Jiangying Cao +7 more
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Shipin gongye ke-jiIn this study, a high-yield aminopeptidase producing strain, Bacillus subtilis LBJ4-5, was isolated from Pixian Douban, and its safety was evaluated through hemolysis and antibiotic sensitivity tests.
Baosong GUO +5 more
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Advanced Science, EarlyView.A microfluidic Herd‐Immunity‐on‐a‐Chip experimentally recreates structured contact networks to quantify viral transmission dynamics. By controlling susceptible, infected, and non‐susceptible populations, the platform reveals how contact topology governs the reproduction number, outbreak propagation, herd‐immunity–like behavior, and intervention ...
Jiande Zhang +6 more
wiley +1 more source
Activity of Alanine aminopeptidase and its isoenzyms partially purified from the urine of chronic renal failure patients. [PDF]
Kirkuk Journal of Science, 2008 The study was performed on 50 urine specimens of patients with chronic renal failure ,in addition to the 92 healthy specimens as a control group. The results of the study revealed that Alanine aminopeptidase (AAP) activity of chronic renal failure ...
Ferah G. Al-Salihi, Tagreed U. AL-Akabie
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Midgut proteases from larval spodoptera littoralis (lepidoptera: noctutoae) [PDF]
, 1992 The presence and properties of proteases present in larval midgut extracts from Spodoptera littoralis was investigated. Trypsin and chymotrypsin activities were found mainly in the midgut lumen while leucine aminopeptidase and dipeptidyl aminopeptidase ...
Lee, Michael James, Lee, M.J
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