Results 1 to 10 of about 9,787 (160)

Unexpected Acute Toxicity of Aminopterin [PDF]

Nature, 1964
THIS communication records the occurrence of a somewhat unusual form of acute toxicity which was observed in the course of an experiment designed to investigate the possible carcinogenicity of aminopterin. As part of this investigation aminopterin (C grade) (California Corporation for Biochemical Research, Los Angeles) was examined in new-born mice ...
B, TOTH, P, SHUBIK
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Serum Proteins in Aminopterin Treated Rats

Experimental Biology and Medicine, 1959
SummaryDifferent fractions of serum proteins were determined by paper electrophoresis in folic acid deficient and pair-fed normal rats. Total serum protein was low and plasma fibrinogen was significantly high in the deficient animals. There was a significant decrease in albumin and γ-globulin, considerable increase in α2-globulin, with no significant ...
K, ROHATGI, S, BANERJEE
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The first achievement of complete remission in childhood leukemia by treatment with the folic acid antagonist aminopterin. [PDF]

Haematologica, 2022
Izraeli S.
europepmc   +1 more source

DHFR Inhibitors Display a Pleiotropic Anti-viral Activity Against SARS-CoV-2: Insights Into the Mechanisms of Action [PDF]

Viruses, 2023
Iaconis D, Caccuri F, Manelfi C, Talarico C, Bugatti A, Filippini F, Zani A, Novelli R, Kuzikov M, Ellinger B, Gribbon P, Riecken K, Esposito F, Corona A, Tramontano E, Beccari AR, Caruso A, Allegretti M.   +17 more
europepmc   +2 more sources

Computational and Experimental Drug Repurposing of FDA-Approved Compounds Targeting the Cannabinoid Receptor CB1. [PDF]

Pharmaceuticals (Basel), 2023
Criscuolo E, De Sciscio ML, De Cristofaro A, Nicoara C, Maccarrone M, Fezza F.   +5 more
europepmc   +1 more source

Aminopterin [PDF]

, 2020
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Crystal structure of dihydrofolate reductase from the filarial nematode W. bancrofti in complex with NADPH and folate. [PDF]

PLoS Negl Trop Dis, 2023
Lange K, Frey KM, Eck T, Janson CA, Gubler U, Goodey NM.   +5 more
europepmc   +1 more source

Aminopterin Sodium [PDF]

, 2020
openaire   +1 more source

QSPR analysis of anticancer drugs using the Euler-Sombor index and theoretical insights on its minimum value for unicyclic graphs. [PDF]

Sci Rep
Shetty S, Rakshith BR, Udupa NVS.
europepmc   +1 more source

Exploring the history of an unsung hero in pioneering biomedical research: Dr Yellapragada Subbarow. [PDF]

Ann Med Surg (Lond)
Kutikuppala LVS, Sharma S, Madhavrao C, Rangari G, Misra AK, Katiboina SR, Saggurthi P, Varshitha G.   +7 more
europepmc   +1 more source