Artificial metabzyme-driven metabolic reprogramming and precision oncology. [PDF]
Clin Transl MedClinical and Translational Medicine, Volume 15, Issue 2, February 2025.
Hu X, Ling D.
europepmc +2 more sources
Studies on the relation between heme and nucleic acid syntheses in erythroid cell. II. Nucleic acid synthesis in erythroblast of anemic rat treated with aminopterin and bromouracil [PDF]
, 1968 With the bone marrow of anemic rats, which had received the repeated injections of phenylhydrazine once a day for three to four days, the effects of aminopterin and bromouracil on the nucleic acid metabolism of erythroblasts were observed in vivo ...
Shigehisa, Morio
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Studies on the relation between heme and nucleic acid syntheses in erythroid cell. 3. Nucleolus of erythroblast, changes in relation with cell specialization [PDF]
, 1969 The disappearance of nucleolus has been traced in the rat erythroid cells in relation with the cell specialization under varying conditions, i. e. in anemia with or without treatment by bromouracil and aminopterin.
Shigehisa, Morio
core +1 more source
Differential chemosensitivity to antifolate drugs between RAS and BRAF melanoma cells. [PDF]
, 2014 BACKGROUND: The importance of the genetic background of cancer cells for the individual susceptibility to cancer treatments is increasingly apparent.
Arozarena, Imanol +5 more
core +2 more sources
Induction of morphological aberrations by enzyme inhibition in Drosophila melanogaster [PDF]
, 1969 Zusatz zum Futter vonDrosophila melanogaster von 5-Fluoro-2-deoxyuridin oder Aminopterin induziert überzählige Skutellar- und Dorsozentralborsten sowie gekerbte Flügel.
Bijlsma, R. +4 more
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Studies on the relation between heme and nucleic acid syntheses in erythroid cell. I. Effects of aminopterin and bromouracil on hemopoiesis and hemoglobin synthesis in anemic rat [PDF]
, 1968 For the purpose to see how the suppression of the nucleic acid synthesis disturbs the cell specialization process the author observed the erythroid cell specialization in anemic rats by treating them with aminopterin (AP) and 5-bromouracil (BU).
Shigehisa, Morio
core +1 more source
Drugs and drug-like molecules can modulate the function of mucosal-associated invariant T cells [PDF]
, 2017 The major-histocompatibility-complex-(MHC)-class-I-related molecule MR1 can present activating and non-activating vitamin-B-based ligands to mucosal-associated invariant T cells (MAIT cells). Whether MR1 binds other ligands is unknown. Here we identified
A Kurioka +67 more
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Dynamics of antifolate transport via the reduced folate carrier and the membrane folate receptor in murine leukaemia cells in vitro and in vivo [PDF]
, 2008 Murine L1210 leukaemia cells expressing either the reduced folate carrier (RFC) or the membrane folate receptor (MFR) were studied in vitro and in vivo to assess the dynamics of membrane transport of two categories antifolates; folate-based ...
Comijn, Elizabeth +7 more
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Bvr-1, a Restriction Locus of a Type C RNA Virus in the Feline Cellular Genome: Pleiotropic Restriction of Endogenous BALB Virus in Cat x Mouse Somatic Cell Hybrids [PDF]
, 1978 Bvr-1 is a dominant X-linked feline gene which restricts the replication of B-tropic murineleukemia virus (B-MuLV) in somatic cell hybrids between murine BALB/c-RAG cells and FL-74 feline cells.
O\u27Brien, Stephen J. +1 more
core +2 more sources
Folate-based single cell screening using surface enhanced Raman microimaging [PDF]
, 2016 Recent progress in nanotechnology and its application to biomedical settings have generated great advantages in dealing with early cancer diagnosis.
Bordi, Federico +11 more
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