Results 31 to 40 of about 9,787 (160)
Birth Defects Research, Volume 118, Issue 1, January 2026.ABSTRACT Background Adverse birth outcomes are important public health measures and account for a substantial public health burden. There is considerable diversity of these health endpoints, as well as in the many factors suspected or recognized to increase their risk.
Paul J. Villeneuve +18 more
wiley +1 more source
Epidemiologic aspects of neural tube defects in South East Iran [PDF]
, 2006 Objectives: To investigate the rate of neural tube defects (NTDs) and their relation to gender, maternal age, consanguineous marriage, season, and drug consumption in Birjand, Iran.
Afshar, M., Farhud, D., Golalipour, M.J.
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Advanced Science, Volume 12, Issue 44, November 27, 2025.This study developed mAb‐5F2, a monoclonal antibody targeting conserved GP4 residues (Q48/I50), which blocks the GP4‐CD163 interaction, resulting in a 78–85% reduction in viral entry. Porcineized 5F2‐pFc prevented mortality in infected piglets, reduced pulmonary viral loads, and minimized lesions. This broad‐spectrum antibody platform overcomes vaccine
Xu Chen +12 more
wiley +1 more source
Biotechnology and Bioengineering, Volume 122, Issue 11, Page 3192-3204, November 2025.ABSTRACT Despite evidence that they are not functional or infective, retrovirus‐like particles (RVLPs), originating from endogenous proviral sequences in Chinese hamster ovary (CHO) cells, present a safety risk for biotherapeutics manufactured using this cell line due to their resemblance to other mammalian leukemia viruses.
Matthew Stuible +8 more
wiley +1 more source
Genetic and serological heterogeneity of the supertypic HLA-B locus specificities Bw4 and Bw6 [PDF]
, 1989 Gene cloning and sequencing of the HLA-B locus split antigens B38 (B16.1) and B39 (B16.2) allowed localization of their subtypic as well as their public specificities HLA-Bw4 or -Bw6 to the c~-helical region of the c~ 1 domain flanked by the amino acid ...
Engler-Blum, G. +5 more
core +1 more source
Small, Volume 21, Issue 40, October 9, 2025.Immunogenicity evaluation in patients receiving mAb therapy is becoming the standard of care in healthcare systems worldwide. Nevertheless, current methods for anti‐drug antibody determination suffer from drug interference and/or inability to be performed at the point‐of‐care (POC).
Frans Kokojka +4 more
wiley +1 more source
Birth Defects Research, Volume 117, Issue 9, September 2025.ABSTRACT Certain medications, when used during pregnancy, are known to impact human prenatal development. Historically, little attention has been given to the impact of in utero exposure on the developing brain, despite the significance of known teratogen‐induced neurodevelopmental difficulties.
M. Bluett‐Duncan +14 more
wiley +1 more source
Introduction and Expression of a Rabbit β-globin Gene in Mouse Fibroblasts [PDF]
, 1979 The cloned chromosomal rabbit ß-globin gene has been introduced into mouse fibroblasts by DNA-mediated gene transfer (transformation). In this report, we examine the expression of the rabbit gene in six independent transformants that contain from 1 to 20
Axel, R. +5 more
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Twenty Years of the Paediatric Radiation Oncology Society
Pediatric Blood &Cancer, Volume 72, Issue 7, July 2025.ABSTRACT In 2005, the Paediatric Radiation Oncology Society (PROS), a multi‐professional association to promote radiotherapy for children and young people, was created. Its mission has been to educate those involved in this field, and to improve the standards of radiation oncology care for children, adolescents, and young adults across the globe, not ...
Mark N. Gaze +18 more
wiley +1 more source
Spina bifida as a multifactorial birth defect: Risk factors and genetic underpinnings
Pediatric Discovery, Volume 3, Issue 2, June 2025.Abstract Spina bifida is a birth defect resulting from abnormal embryonic development of the neural tube. Though spina bifida is divided into several subtypes, myelomeningocele—the most severe form of spina bifida often associated with a markedly diminished quality of life—accounts for a significant portion of cases.
Ethan S. Wong +13 more
wiley +1 more source