Results 11 to 20 of about 71,233 (300)

Investigating the suitability of high content image analysis as a tool to assess the reversibility of foamy alveolar macrophage phenotypes in vitro. [PDF]

open access: yes, 2020
Many potential inhaled medicines fail during development due to the induction of a highly vacuolated or “foamy” alveolar macrophage phenotype response in pre-clinical studies.
Hoffman, Ewelina   +2 more
core   +2 more sources

Circulating TREM2 as a noninvasive diagnostic biomarker for NASH in patients with elevated liver stiffness

open access: yesHepatology, EarlyView., 2022
Abstract Background and Aims Reliable noninvasive biomarkers are an unmet clinical need for the diagnosis of NASH. This study investigates the diagnostic accuracy of the circulating triggering receptor expressed on myeloid cells 2 (plasma TREM2) as a biomarker for NASH in patients with NAFLD and elevated liver stiffness.
Vineesh Indira Chandran   +17 more
wiley   +1 more source

Rapidly Fatal Multiple Organ Failure of Intravenous Amiodarone: A Case Report and Literature Review. [PDF]

open access: yesClin Case Rep
This graphical abstract illustrates the diagnostic journey of a 75‐year‐old male with severe coughing, breathing difficulties, using the patient's electrocardiogram (ECG) recordings as the pivotal clue for identifying atrial flutter with rapid ventricular response.
BinYu, Li H, Chen X.
europepmc   +2 more sources

Treatment of Electrical Storm with Amiodarone in Brugada Syndrome- an Unexpected Protective Effect [PDF]

open access: yes, 2013
We are reporting on a 53 year old man with proven Brugada syndrome and ICD implantation for resuscitation in context of polymorphic VT. After recurrent arrhythmia he was treated with Amiodarone.
Lambiase, PD, Novak, J
core   +1 more source

Risk factors for amiodarone-induced thyroid dysfunction in Japan

open access: yesJournal of Arrhythmia, 2016
Background: Amiodarone is associated with a number of significant adverse effects, including elevated transaminase levels, pulmonary fibrosis, arrhythmia, and thyroid dysfunction.
Sayoko Kinoshita   +8 more
doaj   +1 more source

Increased serum amiodarone concentration in hypertriglyceridemic patients: Effects of drug distribution to serum lipoproteins

open access: yesClinical and Translational Science, 2022
Amiodarone and its main metabolite, desethylamiodarone (DEA), are highly distributed to serum lipoproteins such as very‐low‐density lipoprotein (VLDL) and low‐density lipoprotein (LDL), which are the carriers of triglyceride and cholesterol.
Naoaki Hashimoto   +5 more
doaj   +1 more source

Adverse reactions of amiodarone [PDF]

open access: yes, 2019
Adverse drug reaction is defined by the World Health Organization as any response to a drug that is noxious and unintended and occurs at a dose normally used in man.
Calvosa, Leonardo   +5 more
core   +1 more source

CASE STUDY EFFECTIVNESS OF AMYODARON USE IN PATIENTS WITH SUPRAVENTRICULAR TACHYCARDIA AND HYPOTHYROIDISM

open access: yesMedical and Health Science Journal, 2019
A woman, 53 years of age, with recurrent supraventricular tachycardia (SVT) with hypothyroidism was thought to be associated with amiodarone use. Patients repeatedly get amiodarone for their arrhythmias, where amiodarone has a broad antiarrhythmic
,Ardyarini Dyah Savitri
doaj   +1 more source

Amiodarone-Induced Pulmonary Toxicity in an Elderly Patient: A Case Report. [PDF]

open access: yesClin Case Rep
ABSTRACT Amiodarone, a widely utilized and effective class III antiarrhythmic agent, carries a significant risk of severe organ toxicities, notably including the pulmonary system. This report details a case of an 82‐year‐old female who developed amiodarone‐induced pulmonary toxicity (APT) following 2 years of standard 200 mg daily maintenance therapy ...
Subedi BK   +4 more
europepmc   +2 more sources

Amiodarone-Induced Pulmonary Toxicity - A Frequently Missed Complication. [PDF]

open access: yes, 2016
IntroductionAmiodarone is often used in the suppression of tachyarrhythmias. One of the more serious adverse effects includes amiodarone pulmonary toxicity (APT).
Dang, Natasha   +4 more
core   +2 more sources

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