Results 41 to 50 of about 63,089 (245)

Randomized comparison of intravenous procainamide vs. intravenous amiodarone for the acute treatment of tolerated wide QRS tachycardia: the PROCAMIO study

European Heart Journal, 2016
Aims Intravenous procainamide and amiodarone are drugs of choice for well-tolerated ventricular tachycardia. However, the choice between them, even according to Guidelines, is unclear.
M. Ortiz, Alfonso Martín, F. Arribas, B. Coll-Vinent, C. del Arco, R. Peinado, J. Almendral   +6 more
semanticscholar   +1 more source

Punicalagin Enhances Autophagy Through Sirtuin 1/FoxO3a Axis to Inhibit Intracellular Mycobacterium Abscessus Infection

Advanced Science, EarlyView.
Punicalagin, a pomegranate molecule, helps the body fight Mycobacterium abscessus. It preferentially boosts interstitial macrophages in the lung, stabilizing mitochondria and switching on the autophagy via SIRT1/FoxO3a, which lowers bacterial load without directly killing bacteria.
Kefan Bi, Bihan Xu, Dan Cao, Kaijin Xu, Ying Zhang   +4 more
wiley   +1 more source

Too Little, Too Late: A Case of a Swift Fatal Culmination of Amiodarone Induced Pulmonary Toxicity in an Adult Male

International Medical Case Reports Journal, 2023
Clement Tan, Pranav Kumar Department of Respiratory Medicine, Mackay Base Hospital, Mackay, Queensland, AustraliaCorrespondence: Clement Tan; Pranav Kumar, Email Clement.Tan@health.qld.gov.au; Pranav.Kumar@health.qld.gov.auAbstract: Amiodarone is a ...
Tan C, Kumar P
doaj  

Amiodarone-Induced Pulmonary Toxicity in a Patient With Paroxysmal Atrial Fibrillation and Recurrence of Pulmonary Toxicity

Van Tıp Dergisi, 2022
Amiodarone is an effective anti-arrhythmic agent widely used for management of supraventricular and ventricular arrhythmias. Amiodarone-induced pulmonary toxicity is one of the most serious side effects of amiodarone therapy.
Nuri Köse, Tarık Yıldırım
doaj   +1 more source

Amiodarone promotes cancer cell death through elevated truncated SRSF3 and downregulation of miR-224

OncoTarget, 2018
Amiodarone is a widely used class III antiarrhythmic agent which prolongs the action potential and refractory period by blockage of several types of myocardial potassium channels.
Yung-Lung Chang, Shu‐Ting Liu, Yi-Wen Wang, Wei-Shiang Lin, Shih-Ming Huang   +4 more
semanticscholar   +1 more source

Continuous electrocardiogram monitoring in porcine model of myocardial ischemia reperfusion

Animal Models and Experimental Medicine, EarlyView.
Wearable technology for continuous electrocardiogram monitoring can be utilized in porcine models of disease. Abstract As cardiovascular disease is the leading cause of global mortality, innovative animal models are vital to demonstrating the translational value of experimental discoveries. Investigations focused on myocardial remodeling after ischemia
Nathaniel Hyams, Roxanne Swagel, Sharon Thomas, Rupak Mukherjee, Alicia Braxton Hickman, Daniel Eldridge, Kristine Helke, Ying Mei, Jean Marie Ruddy   +8 more
wiley   +1 more source

Epicardial electrical heterogeneity after amiodarone treatment increases vulnerability to ventricular arrhythmias under therapeutic hypothermia

PLoS ONE, 2023
Background Amiodarone is commonly used during therapeutic hypothermia (TH) following cardiac arrest due to ventricular arrhythmias. However, electrophysiological changes and proarrhythmic risk after amiodarone treatment have not yet been explored in TH ...
Chin-Yu Lin, Ting-Yung Chang, Yu-Feng Hu, Yu-Cheng Hsieh, Yi-Jen Chen, Hung-I Yeh, Yenn-Jiang Lin, Shih-Lin Chang, Li-Wei Lo, Tze-Fan Chao, Fa-Po Chung, Jo-Nan Liao, Ta-Chuan Tuan, Shih-Ann Chen   +13 more
doaj   +2 more sources

L-Carnitine Ameliorates Amiodarone-Mediated Alveolar Damage: Oxidative Stress Parameters, Inflammatory Markers, Histological and Ultrastructural Insights

Pharmaceuticals
The aim of this study was to assess L-carnitine’s effects on adult male rats’ lung damage brought on by amiodarone, which is a potent antiarrhythmic with limited clinical efficacy due to potentially life-threatening amiodarone-induced lung damage ...
Samy A. Dawood, Ali Alsuheel Asseri, Ayed A. Shati, Refaat A. Eid, Basiouny El-Gamal, Mohamed Samir A. Zaki   +5 more
doaj   +1 more source

Machine learning methods for predicting adverse drug events: A systematic review

British Journal of Clinical Pharmacology, EarlyView.
Abstract Predicting adverse drug events (ADEs) in outpatient settings is crucial for improving medication safety, identifying high‐risk patients and reducing health‐care costs. While traditional methods struggle with the complexity of health‐care data, machine learning (ML) models offer improved prediction capabilities; however, their effectiveness in ...
Niaz Chalabianloo, Fatemeh Ahmadi, Mohammad Ali Omrani, Sheikh S. Abdullah, Neda Rostamzadeh, Atefeh Jafari, Lujain Izzedin, Kamran Sedig, Flory T. Muanda   +8 more
wiley   +1 more source

aMplitude spectral area of ventricular fibrillation and amiOdarone Study in patients with out-of-hospital cArdIaC arrest. The MOSAIC study

Frontiers in Cardiovascular Medicine, 2023
ObjectiveAntiarrhythmic drugs are recommended for out of hospital cardiac arrest (OHCA) with shock-refractory ventricular fibrillation (VF). Amplitude Spectral Area (AMSA) of VF is a quantitative waveform measure that describes the amplitude-weighted ...
Francesca Romana Gentile, Francesca Romana Gentile, Lars Wik, Lars Wik, Elisabete Aramendi, Enrico Baldi, Iraia Isasi, Jon Erik Steen-Hansen, Sara Compagnoni, Sara Compagnoni, Alessandro Fasolino, Alessandro Fasolino, Enrico Contri, Alessandra Palo, Roberto Primi, Sara Bendotti, Alessia Currao, Simone Savastano   +17 more
doaj   +1 more source