Results 21 to 30 of about 47,538 (286)

Percutaneous electrical nerve field stimulation compared to standard medical therapy in adolescents with functional abdominal pain disorders

Frontiers in Pain Research, 2023
IntroductionStandard medical therapy (SMT) in children with functional abdominal pain disorders (FAPD) includes cyproheptadine and amitriptyline. While percutaneous electrical nerve field stimulation (PENFS) has shown benefit, no study has compared ...
Neha R. Santucci, Neha R. Santucci, Rashmi Sahay, Khalil I. El-Chammas, Khalil I. El-Chammas, Kahleb Graham, Kahleb Graham, Mikaela Wheatley, Mikaela Wheatley, Madeleine Vandenbrink, Jennifer Hardy, Lin Fei   +11 more
doaj   +1 more source

Effects of Adding Dexmedetomidine to Amitriptyline on Sciatic Nerve Blockadge in Rats

Medicine Science, 2013
Neurotoxic effects of amitriptyline which is a tricyclic antidepressant limit its use as a local anesthetic. In this study, comparing the effect of combination of different amitrptyline doses with dexmedetomidine on block initiation and termination time ...
Mahmut Durmus, Mukadder Sanli, Erdogan Ozturk, Aytac Yucel, Nurcin Gulhas, M. Ozcan Ersoy   +5 more
doaj   +1 more source

Experimental Pharmacological Research Regarding the Potential Antidepressant Activity Induced by Some Newly Synthesised Dibenzo[a,d]cycloheptene Compounds [PDF]

, 2015
Background. Depression is a relatively frequent encountered mental disorder in the general population, affecting both the quality of the individual life and its ability to perform the social tasks; it is generally accepted that new studies related to ...
Junghină, Adrian, Păunică, Ioana, Scutari, Corina, Ștefănescu, Emil   +3 more
core   +7 more sources

Intestinal Acid Sphingomyelinase Protects From Severe Pathogen-Driven Colitis [PDF]

, 2019
Inflammatory diseases of the gastrointestinal tract are emerging as a global problem with increased evidence and prevalence in numerous countries. A dysregulated sphingolipid metabolism occurs in patients with ulcerative colitis and is discussed to ...
Becker, Katrin A., Ebel, Jana-Fabienne, Hose, Matthias [u.v.m.], Japtok, Lukasz, Klopfleisch, Robert, Meiners, Jana, Palmieri, Vittoria, Schumacher, Fabian, Yusuf, Ayan Mohamud, Zöller, Julia   +9 more
core   +1 more source

The role of central mechanisms in the anti-inflammatory effect of amitriptyline on carrageenan-induced paw edema in rats

Clinics, 2010
OBJECTIVE: The present study was designed to further investigate the effect of amitriptyline, a classical tricyclic antidepressant, on carrageenan-induced paw edema in rats. METHODS: First, amitriptyline was administered intraperitoneally (i.p.) at doses
Valiollah Hajhashemi, Hossein Sadeghi, Mohsen Minaiyan, Ahmad Movahedian, Ardeshir Talebi   +4 more
doaj   +1 more source

A Comparative Analysis of Amytripiline, Flunnarazine and Topiramate in the treatment of Primary Headache

Nepal Journal of Neuroscience, 2021
Introduction Primary headache disorder, characterized by recurrent headache is the most prevalent disease leading to widespread ill health and impaired quality of life.
Babu Ram Pokharel, Gopal Raman Sharma, Prabhaw Upadhyaya, Samip Jung Budhathoki, Santosh Thapa, Jyoti Koirala   +5 more
doaj   +1 more source

Patient perspectives of managing fatigue in ankylosing spondylitis, and views on potential interventions: a qualitative study [PDF]

, 2013
<p>Background: Fatigue is a major component of living with ankylosing spondylitis (AS), though it has been largely over-looked, and currently there are no specific agreed management strategies.</p> <p>Methods: This qualitative ...
A Calin, A van Tubergen, B Belza, D Cote-Arsenault, E Dernis-Labous, Elizabeth Irvine, H Dagfinrud, H Repping-Wuts, Helen Davies, J Kabat-Zinn, J Kabat-Zinn, J Trendall, KGA Adams, MD Atkinson, MG Swain, Michael Dennis, MM Ward, MP Davis, N Aissaoui, National Institute for Health and Clinical Excellence, P Burnard, P Grossman, R Gunaydin, RE Boyatzis, Roxanne Cooksey, S Brophy, S Council:, S Garrett, S Hewlett, S Hultgren, SC Richards, SD Jones, SDH Brophy, Sinead Brophy, Stefan Siebert, Welsh Assembly Government, WH Koh, Y Ibn Yacoub, Y Turan   +38 more
core   +2 more sources

Sleep Dysfunction in Fibromyalgia and Therapeutic Approach Options [PDF]

, 2020
Fibromyalgia, characterised by persistent pain, sleep disturbance, fatigue and cognitive dysfunction, is a central sensitivity syndrome that also involves abnormality in peripheral generators and in the hypothalamic pituitary adrenal axis.
Lawson, Kim
core   +1 more source

Brain concentrations and brain-blood ratios of amitriptyline and nortriptyline in forensic postmortem cases. [PDF]

J Anal Toxicol
van der Meer MZ, Rasmussen BS, Nedahl M, Nielsen MKK.   +3 more
europepmc   +3 more sources

Topical treatment of peripheral neuropathic pain: applying the evidence [PDF]

, 2017
Patients with peripheral neuropathic pain (NP) may only achieve partial pain relief with currently recommended first-line oral treatments, which are also associated with systemic adverse events.
Cruccu, Giorgio, Sommer, Claudia
core   +1 more source