Results 61 to 70 of about 56,967 (294)

Preclinical discovery of duloxetine for the treatment of depression [PDF]

open access: yes, 2012
Introduction: Affective disorders, including major depressive disorder (MDD), are among the most severely disabling mental disorders, and in many cases areIntroduction: Affective disorders, including major depressive disorder (MDD), are among the most ...
Berrocoso Domínguez, Esther María   +4 more
core   +2 more sources

Interstitial Cystitis/Bladder Pain Syndrome in Men

open access: yesNeurourology and Urodynamics, EarlyView.
ABSTRACT Aims In April 2025, the Wake Forest Institute for Regenerative Medicine hosted a Global Consensus meeting on interstitial cystitis/bladder pain syndrome (IC/BPS) in Winston‐Salem, NC. The goal of this meeting was to establish attainable targets in phenotyping, diagnosis, and biomarkers for IC/BPS.
Madeline Snipes   +5 more
wiley   +1 more source

Long-Term Pulmonal Therapy of Cystic Fibrosis-Patients with Amitriptyline

open access: yesCellular Physiology and Biochemistry, 2016
Background/Aims: Several recent clinical studies revealed an accumulation of ceramide in bronchial epithelial cells of patients with cystic fibrosis (CF).
Constantin Adams   +8 more
semanticscholar   +1 more source

A geriatrician's approach to managing the complex older adult with obesity

open access: yesObesity, EarlyView.
Abstract The prevalence of obesity in older adults is rapidly increasing due to the demographic shift occurring globally. Older adults with obesity face health care challenges due to multimorbidity, functional dependency, and disability. This population often has prior history of struggles through weight‐loss attempts during the middle years of life ...
Shenbagam Dewar
wiley   +1 more source

European Consensus on Functional Bloating and Abdominal Distension—An ESNM/UEG Recommendations for Clinical Management

open access: yesUnited European Gastroenterology Journal, EarlyView.
ABSTRACT Introduction Abdominal distension is an objective visible sign of increased abdominal girth. Bloating is a feeling of abdominal fullness and discomfort. Bloating may be associated or not with abdominal distension. Bloating and abdominal distension are among the most commonly reported gastrointestinal symptoms and may be associated with both ...
Chloé Melchior   +20 more
wiley   +1 more source

Effectiveness of Multidisciplinary Treatment Compared to Single Discipline Treatment of Female Chronic Pelvic Pain: A Systematic Review and Meta‐Analyses

open access: yesBJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Background Chronic pelvic pain (CPP) is persistent pain perceived to originate in the pelvis, lasting ≥ 3 months. Due to its multifactorial presentation, multidisciplinary treatment may provide optimal care. Objective Systematic review with meta‐analysis of multidisciplinary (≥ 2 of medical, psychology, physiotherapy, nursing, or dietetics ...
Danielle McReynolds   +4 more
wiley   +1 more source

Headache in a patient with Klinefelter's syndrome and hyperostosis frontalis interna. [PDF]

open access: yes, 2007
Hyperostosis frontalis interna (HFI) has been reported in older women, but reports in men are rare. We present a novel case of migraine headache in a gentleman with Klinefelter's syndrome and HFI, along with a discussion of possible pathophysiologic ...
Liebeskind, David S   +2 more
core   +2 more sources

Amitriptyline for fibromyalgia in adults

open access: yesCochrane Database of Systematic Reviews, 2015
This is an updated version of the original Cochrane review published in Issue 12, 2012. That review considered both fibromyalgia and neuropathic pain, but the efficacy of amitriptyline for neuropathic pain is now dealt with in a separate review. Amitriptyline is a tricyclic antidepressant that is widely used to treat fibromyalgia, and is recommended in
Peter Cole   +4 more
openaire   +3 more sources

Drug‐facilitated crime: A review of findings between 2019 and 2023

open access: yesJournal of Forensic Sciences, EarlyView.
Abstract Drug‐facilitated crime (DFC) is a criminal act (e.g., assault, robbery, or sexual assault) in which the perpetrator uses drugs to impair the victim's ability to resist, remember, or recognize the crime being committed. Ethanol is commonly implicated in DFC casework, but limited data are published on other substances currently implicated in ...
Meaghan R. Hessler   +2 more
wiley   +1 more source

Fatal drug overdoses in healthcare workers: A thematic framework analysis of coroner reports

open access: yesAddiction, EarlyView.
Abstract Background and aims Healthcare workers face specific vulnerabilities for drug overdose due to their unique access to medications, clinical knowledge and work‐related stress. This study aimed to understand the characteristics of fatal overdoses in healthcare workers with a view to providing guidance for preventative strategies.
Thikra Algahtani   +6 more
wiley   +1 more source

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