Results 61 to 70 of about 24,814 (247)

Therapy of CF-Patients with Amitriptyline and Placebo - a Randomised, Double-Blind, Placebo-Controlled Phase IIb Multicenter, Cohort-Study

Cellular Physiology and Biochemistry, 2013
Background/Aims: Several recent studies revealed an accumulation of ceramide in bronchial, tracheal and intestinal epithelial cells of mice and patients with cystic fibrosis (CF). Normalization of ceramide concentrations in lungs of CF mice employing the
Lutz Nährlich, Jochen G. Mainz, Constantin Adams, Corinna Engel, Gloria Herrmann, Vanya Icheva, Josefine Lauer, Caroline Deppisch, Andreas Wirth, Katy Unger, Ute Graepler-Mainka, Andreas Hector, Susanne Heyder, Martin Stern, Gerd Döring, Erich Gulbins, Joachim Riethmüller   +16 more
doaj   +1 more source

Electrokinetic Manipulations Combined With Direct and Ambient Ionization Mass Spectrometry

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Mass spectrometry (MS) is a powerful analytical technique that typically involves sample preparation and online analytical separation before MS detection. Traditional methods often face bottlenecks in sample preparation and analytical separation, despite the rapid detection capabilities of MS.
Nicholas E. Manicke, Lahiru Wedasingha, Magnus Rydberg   +2 more
wiley   +1 more source

Repeated Administration of Amitriptyline Reduces Oxaliplatin-Induced Mechanical Allodynia in Rats

Journal of Pharmacological Sciences, 2012
Oxaliplatin is a key drug in the treatment of colorectal cancer, but it causes acute and chronic neuropathies in patients. Amitriptyline has widely been used in patients with painful neuropathy.
Hikaru Sada, Nobuaki Egashira, Soichiro Ushio, Takehiro Kawashiri, Masafumi Shirahama, Ryozo Oishi   +5 more
doaj  

Changes in electrical activity of heart during ischemic–reperfusion injury modified by the administration of antidepressants

European Pharmaceutical Journal, 2016
The aim of our work was to investigate the effect of amitriptyline, citalopram and venlafaxine on the heart during ischemic- reperfusion (l-R) injury.
Vicen M., Gulač P., Stankovičová T.
doaj   +1 more source

A Kampo medicine, choreito, evaluated on female lower urinary tract symptoms (LUTS) with bladder pain

Traditional &Kampo Medicine, EarlyView.
Abstract Aim Choreito (CRT) is a pharmaceutical‐grade Kampo medicine and has been widely prescribed for patients with lower urinary tract symptoms (LUTS) and cystitis in Japan. The purpose of this study was to investigate the efficacy and safety of CRT in patients with persisting bladder pain.
Mineo Takei, Yohei Tokita, Marie Hamaguchi, Manami Aishima, Sachiko Ichikura, Ayami Okabe, Seiji Naito, Akira Yokomizo   +7 more
wiley   +1 more source

Efficacy of herbal combination therapy in the management of paroxysmal dizziness: A case series

Traditional &Kampo Medicine, EarlyView.
Abstract Paroxysmal dizziness, which includes disorders such as Meniere's disease and vestibular migraine, is a common but challenging clinical problem. This case series investigates the efficacy of Kampo herbal combinations in treating patients with refractory Meniere's disease and vestibular migraine.
Fumiyuki Goto
wiley   +1 more source

Concomitant Use of Etrasimod With Opioids or Antidepressants in Patients With Ulcerative Colitis—A Safety Analysis

United European Gastroenterology Journal, EarlyView.
ABSTRACT Background Etrasimod is an oral, once‐daily (q.d.), selective sphingosine 1‐phosphate (S1P)1,4,5 receptor modulator for the treatment of moderately to severely active ulcerative colitis (UC). Unlike the S1P receptor modulator ozanimod, etrasimod does not have a molecular structure to inhibit monoamine oxidase (MAO).
Anita Afzali, Miguel Regueiro, Andres J. Yarur, Yamile Zabana, Siew C. Ng, Sujatha Menon, Aoibhinn McDonnell, Krisztina Lazin, Michael Keating, Abhishek Bhattacharjee, Diogo Branquinho, Eustratios Bananis, Laurent Peyrin‐Biroulet   +12 more
wiley   +1 more source

In vitro and in vivo modulation of LPS and carrageenan-induced expression of inflammatory genes by amitriptyline [PDF]

Journal of Pharmacy & Pharmacognosy Research, 2017
Context: Amitriptyline, a tricyclic antidepressant is used for the management of psychological disorders and various types of pain. In the previous work, it is founded that amitriptyline inhibited the migration of polymorphonuclear (PMN) into the site of
Laleh Rafiee, Valiollah Hajhashemi, Shaghayegh Haghjooy Javanmard   +2 more
doaj  

‘I Wish I Fought for Myself More Instead of Just Letting Doctors Dismiss Me’: A Combined Qualitative Analysis of Four Cohorts of Aotearoa New Zealand Endometriosis Patients

Australian and New Zealand Journal of Obstetrics and Gynaecology, EarlyView.
ABSTRACT Background Endometriosis is a chronic condition that affects around 10% of New Zealand women and people presumed female at birth, however, limitations in diagnosis and management mean patients wait a decade on average from symptom onset to diagnosis.
Katherine Ellis, Rachael Wood
wiley   +1 more source

CORONIS symposium 2023: Scientific and clinical frontiers in ocular surface innervation

Acta Ophthalmologica, EarlyView.
Abstract The 5th CORONIS Symposium, held during the 2023 Congress of the European Association for Vision and Eye Research (EVER), highlighted the growing importance of ocular surface innervation in eye surface disorders. This article summarises the insights and perspectives shared during the symposium, which focused on the clinical relevance of ocular ...
Anat Galor, Juana Gallar, M. Carmen Acosta, Víctor Meseguer, José Manuel Benítez‐Del‐Castillo, Oliver Stachs, Nóra Szentmáry, Piera Versura, Wolfgang G. K. Müller‐Lierheim, Carlos Belmonte, Jesús Pujol‐Martí   +10 more
wiley   +1 more source