Results 71 to 80 of about 56,967 (294)
New players in the preventive treatment of migraine. [PDF]
, 2015 Migraine is a common, chronic disorder of the brain causing much disability, as well as personal, familial and societal impact. Several oral preventive agents are available in different countries for the prevention of migraine, but none have performed ...
Mitsikostas, Dimos D, Rapoport, Alan M
core +3 more sources
Scientific Reports, 2016 Antidepressants, prescribed as first line treatment of neuropathic pain, have a limited efficacy and poorly tolerated side effects. Because recent studies pointed out the implication of astroglial connexins (Cx) in both neuropathic pain and ...
T. Jeanson +9 more
semanticscholar +1 more source
Australian and New Zealand Journal of Obstetrics and Gynaecology, EarlyView.ABSTRACT Background Endometriosis is a chronic condition that affects around 10% of New Zealand women and people presumed female at birth, however, limitations in diagnosis and management mean patients wait a decade on average from symptom onset to diagnosis.
Katherine Ellis, Rachael Wood
wiley +1 more source
Amitriptyline induces mitophagy that precedes apoptosis in human HepG2 cells
Genes & cancer, 2016 Systemic treatments for hepatocellular carcinoma (HCC) have been largely unsuccessful. This study investigated the antitumoral activity of Amitriptyline, a tricyclic antidepressant, in hepatoma cells.
Marina Villanueva-Paz +14 more
semanticscholar +1 more source
Adult‐Onset Dystonia‐Parkinsonism: Do Not Forget SERAC1
Movement Disorders Clinical Practice, EarlyView.
Giulia Scacciatella +15 more
wiley +1 more source
Acta Paediatrica, EarlyView.ABSTRACT Aim The aim of this review is to systematically summarise the evidence on the effectiveness of riboflavin (vitamin B2) or supplements containing riboflavin in preventing paediatric migraines. Methods This systematic review followed the Joanna Briggs Institute methodology and is reported to adhere to the Preferred Reporting Items for Systematic
Elisa Martello +13 more
wiley +1 more source
Clinical pharmacogenetics implementation consortium guideline (CPIC) for CYP2D6 and CYP2C19 genotypes and dosing of tricyclic antidepressants: 2016 update [PDF]
, 2017 CYP2D6 and CYP2C19 polymorphisms affect the exposure, efficacy and safety of tricyclic antidepressants (TCAs), with some drugs being affected by CYP2D6 only (e.g., nortriptyline and desipramine) and others by both polymorphic enzymes (e.g., amitriptyline,
Bishop, Jeffrey R. +13 more
core +1 more source
Pharmacology Research & Perspectives, 2016 Neuritic degeneration and synaptic loss are features of both neuroinflammation and neurodegenerative disease. The tricyclic antidepressant amitriptyline has neurotrophic and anti‐inflammatory properties and acts as a novel agonist of the neurotrophin Trk
Eimear O'Neill +4 more
semanticscholar +1 more source
Opsoclonus‐Myoclonus: Not Always Paraneoplastic
Movement Disorders Clinical Practice, EarlyView.
Fernanda Lustosa Cabral Gomez +4 more
wiley +1 more source
Suicide Deaths in People With Bipolar Disorder: Characteristics and Treatments at Time of Death
Bipolar Disorders, EarlyView.ABSTRACT Objectives This study aimed to compare suicide deaths in those with or without bipolar disorder (BD), taking into particular consideration the degree to which treatment at the time of death, according to toxicology data, reflects evidence‐based pharmacotherapy.
Ayal Schaffer +7 more
wiley +1 more source