Results 41 to 50 of about 459,078 (268)

Combining PDMS Composite and Plasmonic Solid Chemosensors: Dual Determination of Ammonium and Hydrogen Sulfide as Biomarkers in a Saliva Single Test

open access: yesChemosensors
In recent years, in the field of bioanalysis, the use of saliva as a biological fluid for the determination of biomarkers has been proposed. Saliva analysis stands out for its simplicity and non-invasive sampling.
Belen Monforte-Gómez   +3 more
doaj   +1 more source

Ammonium and methyl ammonium transport by RhAG

open access: yesThe FASEB Journal, 2012
The erythroid Rh protein (RhAG) is one component of the “Rh complex” that is known for its immunogenic characteristics. Recently, a role of RhAG in transport of ions has been proposed. In this study, we characterized NH 3 /NH 4 ...
Tolga Caner   +4 more
openaire   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Endophytic Expression of nif Genes of Azoarcus sp. Strain BH72 in Rice Roots

open access: yesMolecular Plant-Microbe Interactions, 1999
Transcriptional fusions of gusA and gfp to the nifH gene as well as immunogold labeling with antibodies against the iron protein of nitrogenase revealed high nitrogenase gene expression levels of the endophyte Azoarcus sp.
Tanja Egener   +2 more
doaj   +1 more source

Removal of nitrogen and phosphorus from water by sludge-based biochar modified by montmorillonite coupled with nano zero-valent iron

open access: yesWater Science and Technology, 2022
Biochar prepared by thermal decomposition of sewage sludge is a new adsorbent for sludge resource utilization and aquatic environmental treatment. In this study, sewage sludge was used as raw material for the preparation of pyrolysis sludge-based biochar.
Dezhi Xu   +8 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Anthocyanin Production through Callus Culture of Apple: Effect of Nitrogen Source and Concentration of Magnesium [PDF]

open access: yesمجله بیوتکنولوژی کشاورزی, 2015
Anthocyanins have attracted a great deal of attention due to their capability in protecting humans from chronic diseases. Production of natural anthocyanins from fresh plant material has many limitations. Therefore, the use of plant biotechnology for the
Farshad Kakavand, Nasser Mahna
doaj   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Modeling the Ability of a Maize–Olive Agroforestry System in Nitrogen and Herbicide Pollution Reduction Using RZWQM2 and Comparison with Field Measurements

open access: yesAgronomy, 2022
Agricultural pollution models are a valuable tool for researchers and managers to predict and assess the potential contamination from the use of fertilizers and pesticides in the field.
George Pavlidis   +1 more
doaj   +1 more source

A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline

open access: yesFEBS Open Bio, EarlyView.
Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey   +4 more
wiley   +1 more source

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