Results 101 to 110 of about 10,947 (204)

Distribution of the cytochrome P450 CYP2C8*2 allele in Brazzaville, Republic of Congo

International Journal of Infectious Diseases, 2019
Background: Cytochrome P450 (CYP) enzymes are essential in the metabolism of most drugs used today. Single nucleotide polymorphism(s) occurring in CYP genes can adversely affect drug pharmacokinetics, efficacy, and safety. Individuals carrying the CYP2C8*
Simon Marie Peko, Francine Ntoumi, Christevy Vouvoungui, David Nderu, Simon Charles Kobawila, Thirumalaisamy P. Velavan, Félix Koukouikila-Koussounda   +6 more
doaj   +1 more source

Effectiveness and safety of artemether–lumefantrine versus artesunate–amodiaquine for unsupervised treatment of uncomplicated falciparum malaria in patients of all age groups in Nanoro, Burkina Faso: a randomized open label trial [PDF]

, 2015
Paul Sondo, Karim Derra, Seydou Diallo-Nakanabo, Zékiba Tarnagda, Odile Zampa, Adama Kazienga, Innocent Valéa, Hermann Sorgho, Ellis Owusu‐Dabo, Jean‐Bosco Ouédraogo, Tinga Robert Guiguemdé, Halidou Tinto   +11 more
openalex   +1 more source

Efficacy of artesunate–amodiaquine in the treatment of falciparum uncomplicated malaria in Madagascar

Malaria Journal, 2018
Since 2006, the artemisinin-based combination therapy (ACT) are recommended to treat uncomplicated malaria including non Plasmodium falciparum malaria in Madagascar. Artesunate–amodiaquine (ASAQ) and artemether–lumefantrine are the first- and second-line
Oméga Raobela, V. Andriantsoanirina, David Gael Rajaonera, T. Rakotomanga, Stéphane Rabearimanana, Fanomezantsoa Ralinoro, D. Ménard, A. Ratsimbasoa   +7 more
semanticscholar   +1 more source

Prevalence of CYP2C8*2 and *3 among Eritreans and its Potential Impact on Artesunate/Amodiaquine Treatment

Pharmacogenomics and Personalized Medicine, 2020
Lidia Habtemikael,1 Mulugeta Russom,2 Iyassu Bahta,2 Selam Mihreteab,3 Araia Berhane,4 Andreas Mårtensson,1 Jose Pedro Gil1,5,6 1Department of Women’s and Children’s Health, International Maternal and Child Health (IMCH), Uppsala ...
Habtemikael L, Russom M, Bahta I, Mihreteab S, Berhane A, Mårtensson A, Gil JP   +6 more
doaj  

Questions about the antimalarial amodiaquine [PDF]

, 2003
Bernard Hirschel
openalex   +1 more source

Chloroquine resistant Plasmodium falciparum malaria in Osogbo Nigeria: efficacy of amodiaquine + sulfadoxine-pyrimethamine and chloroquine + chlorpheniramine for treatment [PDF]

, 2008
TO Ogungbamigbe, Olusola Ojurongbe, PS Ogunro, BM Okanlawon, SO Kolawole   +4 more
openalex   +1 more source

Telfairia occidentalis Potentiates the Antiplasmodial Activity of Artemisinins and Amodiaquine Combination Therapy

, 2020
Aniekan Ebong, Olorunfemi A. Eseyin, Emmanuel I. Etim, Jude E. Okokon, Victor U. Anah, Emmanuel E. Attih, Goodnews E. Charles   +6 more
openalex   +1 more source

Author’s Reply to Bompart: “Artesunate- and Amodiaquine-Associated Extrapyramidal Reactions: Information Gained from an African-Based Risk Management Plan” [PDF]

, 2012
John McEwen
openalex   +1 more source

Amodiaquine ameliorates stress-induced premature cellular senescence via promoting SIRT1-mediated HR repair

Cell Death Discovery
DNA damage is considered to be a potentially unifying driver of ageing, and the stalling of DNA damage repair accelerates the cellular senescence. However, augmenting DNA repair has remained a great challenge due to the intricate repair mechanisms ...
Jie Du, Fuqiang Chen, Chenghong Du, Wenna Zhao, Zihan Chen, Zhenhua Ding, Meijuan Zhou   +6 more
doaj   +1 more source

Use of weight-for-age-data to optimize tablet strength and dosing regimens for a new fixed-dose artesunate-amodiaquine combination for treating falciparum malaria

Bulletin of the World Health Organization
OBJECTIVE: To test a novel methodology to define age-based dosing regimens for the treatment of malaria with a new, user-friendly, blister-packaged fixed-dose combination of artesunate and amodiaquine.
Walter RJ Taylor, Dianne J Terlouw, Piero L Olliaro, Nicholas J White, Philippe Brasseur, Feiko O ter Kuile   +5 more
doaj   +1 more source