Results 131 to 140 of about 11,371,265 (168)

Synthesis of structural analogues of hexadecylphosphocholine and their antineoplastic, antimicrobial and amoebicidal activity

European Journal of Medicinal Chemistry, 2015
Twelve derivatives of hexadecylphosphocholine (miltefosine) were synthesized to determine how the position and length of the alkyl chain within the molecule influence their biological activities. The prepared alkylphosphocholines have the same molecular formula as miltefosine.
Lukáš Timko, Eva Fischer-Fodor, Mária Garajová, Martin Mrva, Gabriela Chereches, František Ondriska, Marián Bukovský, Miloš Lukáč, Janka Karlovská, Janka Kubincová, Ferdinand Devínsky   +10 more
openaire   +3 more sources

Correlation of radical-scavenging capacity and amoebicidal activity of Matricaria recutita L. (Asteraceae)

Experimental Parasitology, 2017
Some Acanthamoeba strains are able to cause Granulomatous Amoebic Encephalitis (GAE) and Acanthamoeba keratitis (AK) worldwide because of their pathogenicity. The treatment of Acanthamoeba infections is complicated due to the existence of a highly resistant cyst stage in their life cycle. Therefore, the elucidation of novel sources of anti-Acanthamoeba
Soumaya Hajaji, Ines Sifaoui, Atteneri López-Arencibia, María Reyes-Batlle, Ignacio A. Jiménez, Isabel L. Bazzocchi, Basilio Valladares, José E. Pinero, Jacob Lorenzo-Morales, Hafidh Akkari   +9 more
openaire   +3 more sources

Amoebicidal thymol analogues against brain-eating amoeba, Naegleria fowleri

Bioorganic Chemistry
Naegleria fowleri, known as the brain-eating amoeba, is the pathogen parasite that causes primary amoebic meningoencephalitis. None of the currently available therapies are fully effective, mainly due to the inefficacy of pharmacotherapy. In this regard,
JOSÉ E Piñero, Ignacio Antonio Jiménez Diaz, Inés Sifaoui   +2 more
exaly   +2 more sources

The amoebicidal activity of three substances derived from benzothiazole on Acanthamoeba castellanii cysts and trophozoites and its cytotoxic potentials.

Acta Tropica, 2021
Acanthamoeba species are free-living amoebae isolated from many ecological areas such as swimming pools, dams, lakes, soil, and air filters. These amoebae are usually causing granulomatous amebic encephalitis and amebic keratitis in immunosuppressive ...
N. Ozpinar, G. Çulha, Tuğba Kaya, H. Yucel   +3 more
semanticscholar   +1 more source

Amoebicidal Activity of Multipurpose Contact Lens Solutions

Eye & Contact Lens: Science & Clinical Practice, 2005
To compare the amoebicidal activity of two commercially available multipurpose contact lens care systems, by using cyst and trophozoite growth of two strains each of Acanthamoeba castellanii and Acanthamoeba polyphaga.Trophozoites and cysts of Acanthamoeba species, isolated from corneal ulcers and an ATCC strain, were exposed to two commonly used ...
Sally L, Buck, Ruth A, Rosenthal, Barry A, Schlech   +2 more
openaire   +2 more sources

Separation of Soluble Amoebicidal and Tumoricidal Activity of Activated Macrophages

The Journal of Protozoology, 1992
ABSTRACT. Macrophage‐conditioned medium (MøCM) prepared from mouse peritoneal macrophages activated in vivo with bacillus Calmette‐Guérin (BCG) or Propionibacterium acnes and triggered with lipopolysaccharide in vitro contained tumoricidal and amoebicidal activity.
K, Fischer-Stenger, G A, Cabral, F, Marciano-Cabral   +2 more
openaire   +2 more sources

In Vitro Amoebicidal Activity of Propolis on Acanthamoeba castellanii

Journal of Ocular Pharmacology and Therapeutics, 2007
The aim of this study was to investigate the in vitro effects of an ethanolic extract of propolis on the growth and adherence of Acanthamoeba castellanii trophozoites and cysts.The effect of propolis with concentrations of 8.0, 6.0, 5.0, 4.0, 3.0, and 2.0 mg/mL on the proliferation of A.
Topalkara, Aysen, Vural, Ayse, Polat, Zubeyde, Toker, Mustafa I., Arici, Mustafa K., Ozan, Fatih, Cetin, Ali   +6 more
openaire   +3 more sources

In vitro amoebicidal and antioxidant activities of some Tunisian seaweeds

Experimental Parasitology, 2017
Free-living amoebae of genus Acanthamoeba are opportunistic pathogens widely distributed in the environment, and are the causative agents of several humans' infections, such as Acanthamoeba keratitis, Granulomatous Amoebic Encephalitis and also disseminated infections.
Olfa, Chiboub, Leila, Ktari, Ines, Sifaoui, Atteneri, López-Arencibia, Maria, Reyes-Batlle, Mondher, Mejri, Basilio, Valladares, Manef, Abderrabba, José E, Piñero, Jacob, Lorenzo-Morales   +9 more
openaire   +2 more sources

The amoebicidal activity and toxicity of natural emetine, (±)-2-dehydroemetine and (−)-2-dehydroemetine

Annals of Tropical Medicine and Parasitology, 1968
R A Neal
exaly   +2 more sources

Amoebicidal activity of the antifungal antibiotic sinefungin against Entamoeba histolytica

Transactions of the Royal Society of Tropical Medicine and Hygiene, 1984
The antifungal antibiotic sinefungin, a potent inhibitor of methyl transferases and a potential inhibitor of polyamine biosynthesis, exhibited marked cytolytic activity against Entamoeba histolytica in vitro with respect to all the amoeba strains tested. Strains of high and low virulence displayed equal sensitivity to the antibiotic.
A, Ferrante, I, Ljungström, G, Huldt, E, Lederer   +3 more
openaire   +2 more sources