Results 141 to 150 of about 11,371,265 (168)

ChemInform Abstract: SYNTHESIS AND AMOEBICIDAL ACTIVITY OF NEW QUINAZOLONES

Chemischer Informationsdienst, 1980
AbstractNach einem bereits beschriebenen Verfahren werden aus substituierten Anthranilsäuren und Arylisothio‐ cyanaten die Chinazolone (I) erhalten, die mit den Chloraeetylpiperazinen (II) zu den 2‐Methylthio‐3‐ary1‐chinazoIonen (III) reagieren.
M. SHARMA, K. SHANKER, K. P. BHARGAVA, K. KISHOR   +3 more
openaire   +1 more source

ChemInform Abstract: AMOEBICIDAL AND FUNGICIDAL ACTIVITIES OF NEW QUINAZOLONES

Chemischer Informationsdienst, 1982
AbstractDie durch Kondensation der Anthranilsäuren (I) mit Benzoylchlorid (II) zugänglichen Phenylbenzoxazinone (III) lassen sich mit den Peptiden (IV) zu den Chinazolonen (V) umsetzen.
R. C. GUPTA, A. K. SAXENA, S. AHMAD, K. SHANKER, K. KISHOR   +4 more
openaire   +1 more source

Amoebicidal activity of the rhizomes and aerial parts of Allium sivasicum on Entamoeba histolytica

Parasitology Research, 2012
Amebiasis is a severe illness caused by Entamoebachistolytica. The aim of this study is to evaluate the in vitro amebicidal activity of the rhizomes and aerial parts of Allium sivasicum, an endemic plant species from the flora of Turkey. Both extracts showed a time- and dose-dependent amebicidal action on the trophozoites.
Degerli, S., Berk, S., Tepe, B., Malatyali, E.   +3 more
openaire   +4 more sources

Amoebicidal activity and chemical composition of Pterocaulon polystachyum (Asteraceae) essential oil

Parasitology Research, 2011
Acanthamoeba species are free-living amoebae that constitute an etiological agent of Acanthamoeba keratitis, an illness that may cause severe ocular inflammation and blindness and has a very difficult treatment. These molecules that are found in plants may be an alternative for the development of new drugs.
Ismael Pretto, Sauter, Jaqueline Campiol, dos Santos, Miriam A, Apel, Samuel Paulo, Cibulski, Paulo Michel, Roehe, Gilsane Lino, von Poser, Marilise Brittes, Rott   +6 more
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Soluble amoebicidal factors mediate cytolysis of Naegleria fowleri by activated macrophages

Cellular Immunology, 1986
Murine peritoneal macrophages activated in vivo with Corynebacterium parvum or bacille Calmette-Guérin, in contrast to resident macrophages, demonstrated significant cytolysis of the amoeba, Naegleria fowleri. Catalase and superoxide dismutase, both alone and in combination, failed to inhibit cytolysis of amoebae. N.
S F, Cleary, F, Marciano-Cabral
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Amoebicidal and fungicidal activities of new quinazolones.

Arzneimittel-Forschung, 1982
Eleven quinazolones were synthesized by condensing 2-phenylanthranil with a suitable peptide in pyridine. The compounds synthesized were characterised by their sharp melting points, elemental analysis and IR spectra. The newly synthesized compounds were tested for their amoebicidal and fungicidal activities.
R C, Gupta, A K, Saxena, S, Ahmad, K, Shanker, K, Kishor   +4 more
openaire   +1 more source

In vitro amoebicidal activity of four Peucedanum species on Acanthamoeba castellanii cysts and trophozoites

Parasitology Research, 2011
Amoebic keratitis is difficult to treat without total efficacy in some patients because of cysts, which is less susceptible than trophozoites to the usual treatments. The aim of this study is to evaluate the in vitro amoebicidal activity of the methanolic extracts of Peucedanum caucasicum, Peucedanum palimbioides, Peucedanum chryseum, and Peucedanum ...
Malatyali, Erdogan, Tepe, Bektas, Degerli, Serpil, Berk, Seyda, Akpulat, H. Askin   +4 more
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Polyoxometalates as potent and selective inhibitors of alkaline phosphatases with profound anticancer and amoebicidal activities

Dalton Transactions, 2012
The biological significance of polyoxometalates is well renowned owing to their anticancer, antiviral and antibiotic properties. Here another therapeutic aspect of polyoxometalates has been explored as alkaline phosphatase inhibitors along with the remarked anticancer and amoebicidal properties.
Rabia, Raza, Abdul, Matin, Sundas, Sarwar, Maria, Barsukova-Stuckart, Masooma, Ibrahim, Ulrich, Kortz, Jamshed, Iqbal   +6 more
openaire   +2 more sources

Chemical composition and amoebicidal activity of Piper hispidinervum (Piperaceae) essential oil

Industrial Crops and Products, 2012
Abstract Acanthamoeba , a free-living protozoan widely distributed in the environment, can cause Acanthamoeba keratitis, a significant ocular microbial infection. The illness can result in blindness when not properly treated in the initial stage. Plants of the genus Piper (Piperaceae) are used in folk medicine for the antibacterial, antifungal ...
Ismael Pretto Sauter, Guilherme Evaldt Rossa, Aline Machado Lucas, Samuel Paulo Cibulski, Paulo Michel Roehe, Luiz Antônio Alves da Silva, Marilise Brittes Rott, Rubem Mário Figueiró Vargas, Eduardo Cassel, Gilsane Lino von Poser   +9 more
openaire   +1 more source

Comparative pharmacokinetics and amoebicidal activity of metronidazole and satranidazole in the golden hamster, Mesocricetus auratus

Journal of Antimicrobial Chemotherapy, 1993
The pharmacokinetic properties of metronidazole and satranidazole were studied in the golden hamster (Mesocricetus auratus), at a dose of 80 mg/kg po. Blood and liver samples were collected at frequent time intervals and assayed for metronidazole and satranidazole by HPLC.
A, Pargal, C, Rao, K K, Bhopale, K S, Pradhan, K B, Masani, C L, Kaul   +5 more
openaire   +2 more sources