Results 171 to 180 of about 118,015 (300)

Active Tablet Coating with Amorphous Solid Dispersion of Ibuprofen-HPMCAS from Organic Solution. [PDF]

Pharmaceutics
Raciborska L, Buczkowska EM, Kukuls K, Pētersone L, Mohylyuk V.   +4 more
europepmc   +1 more source

A Hot-Melt Extrusion Risk Assessment Classification System for Amorphous Solid Dispersion Formulation Development. [PDF]

Pharmaceutics, 2022
Kyeremateng SO, Voges K, Dohrn S, Sobich E, Lander U, Weber S, Gessner D, Evans RC, Degenhardt M.   +8 more
europepmc   +1 more source

Bio‐Inspired Molecular Events in Poly(Ionic Liquids)

Advanced Functional Materials, EarlyView.
Originating from dipolar and polar inter‐ and intra‐chain interactions of the building blocks, the topologies and morphologies of poly(ionic liquids) (PIL) govern their nano‐ and micro‐processibility. Modulating the interactions of cation‐anion pairs with aliphatic dipolar components enables the tunability of properties, facilitated by “bottom‐up ...
Jiahui Liu, Marek W. Urban
wiley   +1 more source

Impact of Different Surfactants on Oral Bioavailability of Paclitaxel/HPMC-AS Amorphous Solid Dispersion. [PDF]

Pharmaceutics
Zhang C, Mao S, Yuan J, Ma X, Xing A, Liu X, Chen Y.   +6 more
europepmc   +1 more source

Itraconazole Amorphous Solid Dispersion Tablets: Formulation and Compaction Process Optimization Using Quality by Design Principles and Tools. [PDF]

Pharmaceutics, 2022
Triboandas H, Pitt K, Bezerra M, Ach-Hubert D, Schlindwein W.   +4 more
europepmc   +1 more source

Dissolution Behavior of Amorphous Solid Dispersions

, 2015
Current drug discovery techniques tend to identify potential new drug entities with more complex structures which may pose significant formulation challenges. In particular, an increasingly large number of new drug compounds have extremely poor solubility in water, impacting the bioavailability of the drug.
openaire   +1 more source

Electric Field‐Dependent Conductivity as Probe for Charge Carrier Delocalization and Morphology in Organic Semiconductors

Advanced Functional Materials, EarlyView.
Applying a high electric field to a doped organic semiconductor heats up the charge carrier distribution beyond the lattice temperature, enhancing conductivity. It is shown that the associated effective temperature can be used to extract the effective localization length, which is a characteristic length scale of charge transport and provides ...
Morteza Shokrani, Felix Maximilian Graf, Anton Kompatscher, Dennis Derewjanko, Martijn Kemerink   +4 more
wiley   +1 more source

Prediction of Solvent Penetration Rate-Limited Release of Drug from Amorphous Solid Dispersion Discs of Various Geometries. [PDF]

Mol Pharm
Men S, Chiang Yu Y, Polli JE.
europepmc   +1 more source

Physicochemical and Biochemical Evaluation of Amorphous Solid Dispersion of Naringenin Prepared Using Hot-Melt Extrusion. [PDF]

Front Nutr, 2022
Ishimoto K, Shimada Y, Ohno A, Otani S, Ago Y, Maeda S, Lin B, Nunomura K, Hino N, Suzuki M, Nakagawa S.   +10 more
europepmc   +1 more source

Unveiling Multidimensional Physicochemical Design Principles for Tissue Processing Hydrogels

Advanced Functional Materials, EarlyView.
This study establishes a materials‐based design framework for polymer hydrogels in tissue clearing, linking physicochemical properties to performance in tissue processing, labeling, and imaging. By analyzing rheology, swelling, porosity, antibody diffusion, mechanical performance, and thermochemical stability across platforms, this work provides a ...
Sangjae Kim, Siheon Lee, Jinsoo Na, James Sangmin Choo, Inho Kim, Junsang Doh, Jeong‐Yun Sun, Chang Yeol Lee, Juhyuk Park   +8 more
wiley   +1 more source