Using of amorphous solid dispersion in pharmacy
Tato práce se zaměřuje na strategie zlepšení rozpustnosti a biodostupnosti léčiv, zejména na amorfní pevné disperze. Popisuje klasifikaci, výhody, nevýhody a metody přípravy amorfních pevných disperzí. Uvádí konkrétní příklady komerčních léčiv vyráběných
Zachová, Alena
core
Active Tablet Coating with Amorphous Solid Dispersion of Ibuprofen-HPMCAS from Organic Solution. [PDF]
Raciborska L +4 more
europepmc +1 more source
A Hot-Melt Extrusion Risk Assessment Classification System for Amorphous Solid Dispersion Formulation Development. [PDF]
Kyeremateng SO +8 more
europepmc +1 more source
In Situ Amine Formation to Modulate MOF‐Derived PdIn N‐Doped Carbon Catalysts
An amine‐assisted approach converts PdIn‐MOF into PdIn intermetallic nanoparticles embedded in N‐doped carbon. In situ‐generated amines trigger early Pd nucleation, producing smaller PdIn domains than direct pyrolysis. Amine sterics and basicity tune composition and particle size, while solvent and amine co‐determine textural features.
Gonzalo Egea +9 more
wiley +1 more source
Impact of Different Surfactants on Oral Bioavailability of Paclitaxel/HPMC-AS Amorphous Solid Dispersion. [PDF]
Zhang C +6 more
europepmc +1 more source
Itraconazole Amorphous Solid Dispersion Tablets: Formulation and Compaction Process Optimization Using Quality by Design Principles and Tools. [PDF]
Triboandas H +4 more
europepmc +1 more source
Eutectozymes as Soft Hybrid Materials for Advanced Biocatalysis
Eutectozymes are sustainable hybrid materials that embed a GOx–HRP cascade within hydrophobic eutectogels featuring a dual supramolecular–covalent network. This architecture preserves native enzyme structure and stability, enables efficient heterogeneous biocatalysis in aqueous media, and positions eutectogels as robust platforms for next‐generation ...
Manuel Eduardo Martinez Cartagena +10 more
wiley +1 more source
Prediction of Solvent Penetration Rate-Limited Release of Drug from Amorphous Solid Dispersion Discs of Various Geometries. [PDF]
Men S, Chiang Yu Y, Polli JE.
europepmc +1 more source
Physicochemical and Biochemical Evaluation of Amorphous Solid Dispersion of Naringenin Prepared Using Hot-Melt Extrusion. [PDF]
Ishimoto K +10 more
europepmc +1 more source
High Charge Carrier Mobility in Non‐Conjugated 3D Covalent Organic Frameworks
A non‐conjugated 3D COF constructed via boronate ester linkages from tetraphenylene and pyrene‐based monomers is reported, which exhibits a high charge carrier mobility of 14 ± 1 cm2 V−1 s−1. ABSTRACT π‐Conjugation, π–π stacking, and long‐range order play a central role in determining charge transport efficiency in organic materials.
Joaquín Almarza +11 more
wiley +1 more source

