Results 101 to 110 of about 66,736 (230)

Biodegradation of (Aminomethyl)phosphonic acid (AMPA) by isolated microbial consortia extracted from biological filters at drinking water treatment plants

open access: yesCurrent Research in Biotechnology
The widespread use of glyphosate has significantly increased its presence in drinking water sources. Aminomethylphosphonic Acid (AMPA), a breakdown product of glyphosate, is challenging to remove from water using conventional treatment methods, posing ...
Laura Pickering   +5 more
doaj   +1 more source

Respiratory dysfunction and fatal apnea during pilocarpine‐induced status epilepticus

open access: yesEpilepsia, EarlyView.
Abstract Objective Status epilepticus (SE) is second only to sudden unexpected death in epilepsy as a cause of seizure‐related mortality. The progression of respiratory dysfunction during experimental SE remains poorly characterized. We investigated how pilocarpine‐induced SE affects respiration in mice.
Chengsan Sun   +6 more
wiley   +1 more source

Neuronal hyperexcitability: A key to unraveling hippocampal synaptic dysfunction in Lafora disease

open access: yesEpilepsia, EarlyView.
Abstract Background and Objective Lafora disease (LD) is a rare progressive disorder caused by mutations in the EPM2A or EPM2B genes, characterized by the accumulation of Lafora bodies, drug‐resistant epilepsy, and cognitive decline. To investigate the early molecular mechanisms of LD, we studied electrophysiological changes in the dentate gyrus (DG ...
Cinzia Costa   +17 more
wiley   +1 more source

Treatment approaches in posthypoxic myoclonus: A narrative review with expert opinion

open access: yesEpilepsia, EarlyView.
Abstract Acute posthypoxic myoclonus (PHM) is a neurological complication that typically emerges within 12–48 h following cardiac arrest, often in comatose patients. It can present as generalized, multifocal, or focal myoclonus and has traditionally been associated with poor prognosis.
Marina Romozzi   +7 more
wiley   +1 more source

3′UTR variants of ALS‐linked RNAs modify subcellular and cellular phenotypes

open access: yesThe FEBS Journal, EarlyView.
Our study demonstrates that alternative 3′UTR variants of ALS‐linked transcripts modulate subcellular RNA localization and cytoskeletal architecture. NEFH 3′UTR‐Long promotes nuclear RNA clustering, while SOD1 3′UTR‐Long reduces filopodia formation. These results suggest that 3′UTRs, independent of coding sequences, can influence neuronal phenotypes ...
Melis Savasan‐Sogut   +2 more
wiley   +1 more source

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