Results 141 to 150 of about 150,350 (378)
A neuroeconomic theory of bidirectional synaptic plasticity and addiction [PDF]
Neuronal mechanisms underlying addiction have been attracting attention in neurobiology, economics, neuropsychiatry, and neuroeconomics. This paper proposes a possible link between economic theory of addiction (Becker and Murphy, 1988) and neurobiological theory of bidirectional synaptic plasticity (Bienenstock, Cooper, Munro, 1982) based on recent ...
arxiv
Abstract Objective Status epilepticus (SE) is a condition of neurological emergency, which precipitates various functional and morphological changes in the brain. Due to the risk of drug resistance associated with SE, this study aimed to evaluate a multitargeted approach to treat SE by combining clinically used antiseizure drugs. Methods In this study,
Sana Javaid+7 more
wiley +1 more source
Quantum Chains of Hopf Algebras with Quantum Double Cosymmetry
Given a finite dimensional C^*-Hopf algebra H and its dual H^ we construct the infinite crossed product A=... x H x H^ x H ... and study its superselection sectors in the framework of algebraic quantum field theory.
Nill, Florian, Szlachanyi, Kornel
core +1 more source
Removal of AMPA receptors (AMPARs) from synapses is preceded by transient endocytosis of extrasynaptic AMPARs [PDF]
AMPA receptors (AMPARs) are dynamically regulated at synapses, but the time course and location of their exocytosis and endocytosis are not known. Therefore, we have used ecliptic pHluorin-tagged glutamate receptor 2 to visualize changes in AMPAR surface
Ashby, MC+5 more
core +1 more source
Hippocampal AMPA receptor assemblies and mechanism of allosteric inhibition
Jie Yu+5 more
semanticscholar +1 more source
Copine-6 is a Ca2+ sensor for activity-induced AMPA receptor exocytosis
Summary: The recruitment of synaptic α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) receptors underlies the strengthening of neuronal connectivity during learning and memory. This process is triggered by N-methyl-D-aspartate (NMDA) receptor-
Jing Zhi Anson Tan+10 more
doaj
S 47445 is a novel positive allosteric modulator of alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA) receptors (AMPA-PAM). S 47445 enhanced glutamate's action at AMPA receptors on human and rat receptors and was inactive at NMDA and ...
Sylvie Bretin+18 more
doaj +1 more source
Abstract The Ankyrin 2 (ANK2) gene encodes the ankyrin‐B protein (ANKB), which is involved in the organization and stability of membrane ion channels, transporters, and receptors in cardiomyocytes and neurons. Variants in ANK2 genes are initially reported in long QT syndrome and autism.
Po‐Hsi Lin+5 more
wiley +1 more source
Blockade of adenosine A2A receptors prevents protein phosphorylation in the striatum induced by cortical stimulation [PDF]
©2006 Society for NeurosciencePrevious studies have shown that cortical stimulation selectively activates extracellular signal-regulated kinase 1/2 (ERK1/2) phosphorylation and immediate early gene expression in striatal GABAergic enkephalinergic neurons.
Ferré, Sergi+6 more
core +1 more source
Toxicity of AMPA to the earthworm Eisenia andrei Bouché, 1972 in tropical artificial soil
Aminomethylphosphonic acid (AMPA) - one of glyphosate’s main metabolites - has been classified as persistent in soils, raising concern regarding the widespread use of glyphosate in agriculture and forestry. Glyphosate may have negative or neutral effects
A. Domínguez+7 more
semanticscholar +1 more source