Results 181 to 190 of about 89,264 (312)

Genetic Inactivation of the Serotonin Transporter Dysregulates Expression of Neurotransmission Genes and Genome‐Wide DNA Methylation Levels in the Medial Prefrontal Cortex of Male Rats During Postnatal Development

open access: yesDevelopmental Neurobiology, Volume 85, Issue 3, July 2025.
ABSTRACT Reduced expression of the serotonin transporter (5‐hydroxytryptamine transporter, 5‐HTT) in early life has been associated with a delay in postnatal brain development and endophenotypes of a variety of neuropsychiatric and neurodevelopmental disorders in adolescence and adulthood.
Yvet Kroeze   +9 more
wiley   +1 more source

Quantitative analysis of the interaction between NMDA and AMPA receptors in glutamatergic synapses based on mathematical model

open access: yesNeuroscience Research
NMDA and AMPA receptors are co-localized at most glutamatergic synapses, where their numbers and distribution undergo dynamic changes. Glutamate binds to both the NMDA and AMPA receptors.
Qingchen Guo
doaj  

Loss of Glutaminase 1 in Small Sensory Neurons Prevents Nerve Injury Induced Mechanical Allodynia: Insights From Conditional Knockout Mice

open access: yesEuropean Journal of Pain, Volume 29, Issue 6, July 2025.
ABSTRACT Background Glutamate, the primary neurotransmitter released by nociceptors, is predominantly synthesised by the enzyme Glutaminase 1 (GLS1). The involvement of GLS1 in pain pathways is well supported, as Gls1 heterozygous mice exhibit altered nociception and GLS1 levels increase in the dorsal root ganglia (DRG) under chronic peripheral ...
Anabel Martínez‐Padilla   +4 more
wiley   +1 more source

Regulation of AMPA Receptor–Mediated Synaptic Transmission by Clathrin-Dependent Receptor Internalization [PDF]

open access: bronze, 2000
Heng‐Ye Man   +7 more
openalex   +1 more source

Hyperhomocysteinemia‐Driven Ischemic Stroke: Unraveling Molecular Mechanisms and Therapeutic Horizons

open access: yesFood Science &Nutrition, Volume 13, Issue 7, July 2025.
Neurotoxicity of Hcy. (A figure that best represents the scope of the paper.) Homocysteine can reduce the tightness of endothelial cell connections, increase vascular permeability, and damage the blood–brain barrier. Homocysteine activates various glutamate receptors on the surfaces of neurons and glial cells, triggering excitotoxicity, promoting the ...
Bin Li, Yushun Kou, Lingna Zhang, Lin Yi
wiley   +1 more source

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