Results 181 to 190 of about 140,198 (327)

HSDL2 Suppresses Epileptic Seizures Through Phosphorylation‐Dependent Modulation of the PSD95‐NMDAR Signaling Axis

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 3, March 2026.
In a kainic acid‐induced mouse model of epilepsy, upregulation of HSDL2 in the hippocampus prolonged seizure latency, increased the membrane expression of PSD95, and enhanced its phosphorylation. Concurrently, HSDL2 attenuated the interaction between PSD95 and the NMDAR subunits GluN2A/GluN2B, thereby suppressing NMDAR overactivation, reducing ...
Yan Xia   +5 more
wiley   +1 more source

Feasibility and systems definition study for Microwave Multi-Application Payload (MMAP) [PDF]

open access: yes
Work completed on three Shuttle/Spacelab experiments is examined: the Adaptive Multibeam Phased Array Antenna (AMPA) Experiment, Electromagnetic Environment Experiment (EEE) and Millimeter Wave Communications Experiment (MWCE).
Afifi, M.   +9 more
core   +1 more source

Antidepressant-like effect of guanosine involves activation of AMPA receptor and BDNF/TrkB signaling

open access: green, 2021
Priscila B. Rosa   +14 more
openalex   +2 more sources

Tocotrienols: A Review From Source to Therapeutic Applications

open access: yesFood Frontiers, Volume 7, Issue 2, March 2026.
Tocotrienols demonstrate superior antioxidant, neuroprotective, and anti‐inflammatory properties compared to conventional vitamin E forms, with promising therapeutic applications across multiple disorders when delivered through optimized systems that enhance their inherently limited bioavailability.
Natalia‐Carolina Londoño   +6 more
wiley   +1 more source

Mechanisms of spinal glial activation in chemotherapy‐induced peripheral neuropathy: Focus on microglia and astrocytes

open access: yesIbrain, Volume 12, Issue 1, Page 65-85, Spring 2026.
Chemotherapy‐induced peripheral neuropathy (CIPN) remains a major clinical challenge, with central sensitization considered an important pathological mechanism in its occurrence and persistence. This review focuses on spinal astrocytes and microglia, systematically summarizing the pathological mechanisms of spinal glial cells involved in CIPN caused by
Long Gu, Song Cao, Yonghuai Feng
wiley   +1 more source

Modulation of glutamate metabolism in Niemann-pick disease type C1 mice. [PDF]

open access: yesMol Genet Metab Rep
Cougnoux A   +6 more
europepmc   +1 more source

Potential neuroprotective and therapeutic agents and their mechanisms for irradiation‐induced brain injury

open access: yesIbrain, Volume 12, Issue 1, Page 96-122, Spring 2026.
In this review, agents such baicalein, troxerutin, epigallocatechin gallate, quercetin, melatonin, valproic acid, lithium, neurosteroid progesterone, as well as minocycline have been implicated as neuroprotective agents for irradiation‐induced neurological deficits. Also, agents such as glucocorticoids, methylphenidate, vitamin E, bisdemethoxycurcumin,
Seidu A. Richard   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy