Results 41 to 50 of about 140,198 (327)

Food-induced behavioral sensitization, its cross-sensitization to cocaine and morphine, pharmacological blockade, and effect on food intake [PDF]

, 2006
Repeated administration of abused drugs sensitizes their stimulant effects and results in a drug-paired environment eliciting conditioned activity. We tested whether food induces similar effects.
Le Merrer, Julie, Stephens, David N
core   +1 more source

A Systematic Review and Meta‐Analysis of the Recurrence of Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune encephalitis (AE) is a disease with a potential for recurrence, and patients receive immunotherapy to prevent it. However, there is no consensus on the duration of immunotherapy. This study aimed to determine the recurrence rate and identify the risk factors for AE to provide guidance on the duration of immunotherapy ...
Shangkai Bai, Sen Zhang, Haipei Zhang, Yating Zhang, Junhong Guo, Xiaoyan Yang   +5 more
wiley   +1 more source

Pengembangan Pupuk Ampas dari Ampas Kopi di Banda Aceh

Journal of Community Development & Empowerment, 2020
Tujuan pengabdian ini adalah untuk mengembangkan produk pupuk dari ampas kopi yang diproduksi oleh Madrasah Alia Negeri Banda Aceh (MAN Model). Metode yang digunakan dalam pengembangan produk ini adalah dengan New Product Development agar produk yang dihasilkan mempunyai nilai jual yang baik dan dapat diterima oleh konsumen.
null Aliasuddin, Mirza Tabrani, Nanda Rahmi   +2 more
openaire   +1 more source

Gut Microbiota‐Derived Anandamide Mediates the Therapeutic Effects of Urolithin A on Alcohol‐Induced Cognitive and Social Dysfunction via CB1R‐DRD2‐RAP1 Signaling Axis

Advanced Science, EarlyView.
This study reveals that Urolithin A (UA) counteracts alcohol‐induced cognitive and social dysfunction (AICSD) via a gut microbiome‐dependent mechanism. UA‐enriched Bacteroids sartorii and Parabacteroids distasonis elevate anandamide (AEA), which activates the CB1R‐DRD2‐Rap1 signaling cascade to drive synaptic repair and reduce neuroinflammation ...
Hongbo Zhang, Zibin Li, Yao Xiao, Ji Bian, Caian He, Chao Liu, Lan Gong, Lin Han, Zhigang Liu, Min Wang   +9 more
wiley   +1 more source

Potencial de Chlorophytum comosum para la remediación de suelos contaminados con glifosato

Terra Latinoamericana
El glifosato es un herbicida ampliamente utilizado, pero su uso excesivo ha generado preocupaciones por sus posibles efectos negativos en la salud humana y al ambiente debido a su persistencia en el suelo. La fitorremediación es el uso de la capacidad de
Pedro Sandoval-Estrada, Ana Belem Piña-Guzmán , Dioselina Álvarez-Bernal, Marina Olivia Franco-Hernández, Fabián Robles-Martínez   +4 more
doaj   +1 more source

Determination of hydrophilic–lipophilic balance value and emulsion properties of sacha inchi oil

Asian Pacific Journal of Tropical Biomedicine, 2017
Objective: To determine hydrophilic–lipophilic balance (HLB) value, stability of formulate emulsion and properties of sacha inchi oil. Methods: The physiochemical characteristics of sacha inchi oil were first investigated.
Kiattiphumi Saengsorn, Ampa Jimtaisong
doaj   +1 more source

What causes aberrant salience in schizophrenia? A role for impaired short-term habituation and the GRIA1 (GluA1) AMPA receptor subunit. [PDF]

, 2014
The GRIA1 locus, encoding the GluA1 (also known as GluRA or GluR1) AMPA glutamate receptor subunit, shows genome-wide association to schizophrenia. As well as extending the evidence that glutamatergic abnormalities have a key role in the disorder, this ...
Bannerman, D.M., Barkus, C., Harrison, P.J., Rawlins, J.N.P., Sanderson, D.J., Walton, M.E.   +5 more
core   +1 more source

An Open‐Source Pipeline for Calcium Imaging and All‐Optical Physiology in Human Stem Cell‐Derived Neurons

Advanced Science, EarlyView.
This work introduces an open‐source all‐optical platform for functional phenotyping of human stem cell‐derived neurons. The system integrates optogenetics, calcium imaging, automated acquisition, and analysis to resolve single‐cell and network activity, enabling longitudinal measurements, disease modeling, and pharmacological screening in preclinical ...
Wardiya Afshar‐Saber, Federico M. Gasparoli, Ziqin Yang, Nicole A. Teaney, Rachel Hobson, Lahin Lalani, Gayathri Srinivasan, Dosh Whye, Ranit Karmakar, Elizabeth D. Buttermore, Kellen D. Winden, Cidi Chen, Mustafa Sahin   +12 more
wiley   +1 more source

AMPA-ergic regulation of amyloid-β levels in an Alzheimer’s disease mouse model

Molecular Neurodegeneration, 2018
Background Extracellular aggregation of the amyloid-β (Aβ) peptide into toxic multimers is a key event in Alzheimer’s disease (AD) pathogenesis. Aβ aggregation is concentration-dependent, with higher concentrations of Aβ much more likely to form toxic ...
Jane C. Hettinger, Hyo Lee, Guojun Bu, David M. Holtzman, John R. Cirrito   +4 more
doaj   +1 more source

A Tac1‐Expressing Brainstem Pathway Underlies the Pathogenesis of Trigeminal Neuralgia

Advanced Science, EarlyView.
A critical TG‐Sp5CTac1‐PBNTac1 pathway drives trigeminal neuropathic pain (TNP). Tac1‐expressing parabrachial nucleus (PBNTac1) neurons exhibit heightened responses to innocuous stimuli in TNP, and chemogenetic inhibition of these neurons effectively prevents TNP development.
Liting Sun, Jia‐Jia Wang, Xiang‐Yu Li, Xin‐Yi Lin, Juan Li, Qiu‐Tong Yu, Zi‐Han Wang, Xue‐Ping Gao, Lei Jin, Wei‐Ke Li, Tian‐Lin Cheng, Juan Deng   +11 more
wiley   +1 more source