Results 221 to 230 of about 99,629 (284)

RNA Granules at the Crossroads of Synaptic Dysfunction and Neurodegeneration

Journal of Neurochemistry, Volume 169, Issue 11, November 2025.
Under physiological conditions, neuronal RNA granules (e.g., transport granules, activity‐dependent granules, processing bodies, and stress granules) cooperate to regulate mRNA transport, storage, and localized translation, thereby sustaining synaptic and neuronal functions.
Rita Nóbrega‐Martins, Beatriz Barros‐Santos, Georgia Papadimitriou, Ioannis Sotiropoulos, Benjamin Wolozin, Joana Margarida Silva   +5 more
wiley   +1 more source

Exploring the impact of the stargazin V143L mutation on the dynamics of the AMPA receptor: stargazin complex. [PDF]

Front Cell Neurosci
Gouveia RP, Barreto CAV, Melo R, Carvalho AL, Moreira IS.   +4 more
europepmc   +1 more source

Mutagenesis Reveals a Role for ABP/GRIP Binding to GluR2 in Synaptic Surface Accumulation of the AMPA Receptor

, 2000
Pavel Osten, Latika Khatri, Joey L Perez, Georg Köhr, Guenter Giese, Christopher Daly, Torsten Schulz, Allen Wensky, Laveria M Lee, Edward B. Ziff   +9 more
openalex   +1 more source

Evaluation of a New Riluzole‐Based Compound VA945 on Sodium and Potassium Conductances Expressed by SH‐SY5Y‐ Derived Neurons

Journal of Neurochemistry, Volume 169, Issue 11, November 2025.
The potential capability of a newly synthesized riluzole‐based compound, VA945, to affect neuronal excitability was tested by assessing its ability to modulate the biophysical properties of voltage‐gated sodium (Nav) and Delayed‐Rectifier Potassium (KDR) channels expressed in SH‐SY5Y human neuroblastoma cells differentiated into neurons.
J. Cazzola, F. Talpo, G. Faravelli, C. Donati, S. Maramai, M. Saletti, G. Giuliani, M. Paolino, A. Cappelli, M. Anzini, P. Sommi, A. Vitali, A. Sala, A. Trucco, G. R. Biella, P. Spaiardi   +15 more
wiley   +1 more source

AMPA receptor diffusional trapping machinery as an early therapeutic target in neurodegenerative and neuropsychiatric disorders. [PDF]

Transl Neurodegener
Choquet D, Opazo P, Zhang H.
europepmc   +1 more source

Regulation of Kinetic Properties of GluR2 AMPA Receptor Channels by Alternative Splicing [PDF]

, 2000
Maki Koike‐Tani, Shota Tsukada, Keisuke Tsuzuki, Hiromasa Kijima, Seiji Ozawa   +4 more
openalex   +1 more source

Comparative analysis of androgen and estrogen receptor mRNA expression in adult mouse hippocampus

Journal of Neuroendocrinology, Volume 37, Issue 11, November 2025.
Abstract In hippocampus, androgens and estrogens influence neuronal plasticity via a range of nuclear or membrane‐bound receptors. While much work has focused on determining their functions, a certain vagueness about the cellular expression of established receptors has remained.
Malte Schöbe, Bianka Brunne, Roland A. Bender   +2 more
wiley   +1 more source

Opposite changes in synaptic activity of organotypic rat spinal cord cultures after chronic block of AMPA/kainate or glycine and GABA_A receptors

, 2000
Micaela Galante, Andrea Nistri, Laura Ballerini   +2 more
openalex   +2 more sources

Adaptations to hypoxia in the vertebrate retina

The Journal of Physiology, Volume 603, Issue 21, Page 6517-6531, November 1, 2025.
Abstract figure legend Most animals, including mammals, are susceptible to the damaging effects of hypoxia or ischaemia, where the result is neuronal cell death in the brain. By contrast, some neurons of the mammalian retina are less sensitive to hypoxia. In both brain and retina, neurons may survive if first preconditioned with ischaemia.
Michael G. Jonz
wiley   +1 more source

The diversity of AMPA receptor inhibition mechanisms among amidine-containing compounds. [PDF]

Front Pharmacol
Zhigulin AS, Dron MY, Barygin OI, Tikhonov DB.   +3 more
europepmc   +1 more source