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The AMPA receptors of auditory neurons
Hearing Research, 2000The ionotropic glutamate receptor (GluR) subtype known as the AMPA receptor, which mediates rapid excitatory synaptic transmission in many regions of the nervous system, is composed of four different protein subunits, termed GluRs 1-4. The functional properties of each AMPA receptor are determined by the relative levels of GluRs 1-4 and by post ...
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AMPA Receptor Trafficking and GluR1
Science, 2005In their Research Article “Postsynaptic receptor trafficking underlying a form of associative learning” (1 Apr., p. 83), S. Rumpel et al. draw the important conclusions that “encoding of memories in the lateral amygdala is mediated by AMPA receptor trafficking” and that “synaptic incorporation of AMPARs is necessary for learning.” The key experiment ...
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European Journal of Pharmacology, 1996
A series of (RS)-2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid (AMPA) analogues were evaluated for activity at homo-oligomeric glutamate1-flop (Glu1-flop) receptors expressed in Xenopus oocytes, using the two-electrode voltage clamp technique.
Wahl, P +4 more
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A series of (RS)-2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid (AMPA) analogues were evaluated for activity at homo-oligomeric glutamate1-flop (Glu1-flop) receptors expressed in Xenopus oocytes, using the two-electrode voltage clamp technique.
Wahl, P +4 more
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AMPA receptor trafficking and synaptic plasticity.
Annual Review of Neuroscience, 2002R. Malinow, R. Malenka
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Photocontrol of AMPA Receptors with a Photochromic Ligand
2014Photochromic ligands (PCLs), recently introduced by our group as a tool for researchers in neuroscience, offer the ability to control native receptors with light in a reversible fashion without the need for any genetic manipulation. Here we describe the application of the PCL Azo-Tetrazole-AMPA-3 (ATA-3) to reversibly gate native AMPA-receptors with ...
Martin Sumser, Philipp Stawski
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Synaptic AMPA receptor composition in development, plasticity and disease
Nature Reviews Neuroscience, 2016J. Henley, K. Wilkinson
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Neurology, 2016
In this and forthcoming reviews, a representative clinical case will serve as an introduction to the topic to be discussed. This will provide the basis to address some recent insights from basic neuroscience research on the normal function of the primary target of the disease process involved in the case presented, as well as putative pathophysiologic ...
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In this and forthcoming reviews, a representative clinical case will serve as an introduction to the topic to be discussed. This will provide the basis to address some recent insights from basic neuroscience research on the normal function of the primary target of the disease process involved in the case presented, as well as putative pathophysiologic ...
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Long-Term Potentiation: From CaMKII to AMPA Receptor Trafficking.
Annual Review of Physiology, 2016B. Herring, R. Nicoll
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A Photochromic Agonist of AMPA Receptors
Angewandte Chemie International Edition, 2012Stawski, P.; Sumser, M.; Trauner, D.
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Regulation of distinct AMPA receptor phosphorylation sites during bidirectional synaptic plasticity
Nature, 2000Hey-Kyoung Lee +4 more
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